We are a groundbreaking venture fund investing approximately US$1 billion to bring 2 to 4 new antimicrobials to patients by the end of the decade.

Boston, MA
New @CDCgov report on #AMR in US: ~9.7M infections and more than 50k deaths annually, with substantial costs (~$12 billion) to health care system. Learn more here: arpsp.cdc.gov/artr
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Philanthropy, however, can take drug development only so far. For a problem as significant and costly as antimicrobial resistance, the type of innovation we need will emerge only if policymakers create the conditions for it to flourish cidrap.umn.edu/antimicrobial… #AMR
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"If policymakers want antibiotics that are more precise and less disruptive to beneficial bacteria, they must create the market conditions that make them investable." #AMR
COMMENTARY: We must address the market challenges behind microbiome-sparing antibiotics Interest in antimicrobial drugs designed to minimize microbiome disruption is growing, but we need good policy to support them. Read full piece by Henry Skinner, PhD: bit.ly/3UgVfa5
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AMR Action Fund retweeted
COMMENTARY: We must address the market challenges behind microbiome-sparing antibiotics Interest in antimicrobial drugs designed to minimize microbiome disruption is growing, but we need good policy to support them. Read full piece by Henry Skinner, PhD: bit.ly/3UgVfa5
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"Calls for more targeted antibiotics often gloss over the fundamental market challenges that have stymied investment in antimicrobials and innovation in the field." CEO Henry Skinner on the need to incentivize #AMR R&D to drive gut-sparing innovation via @CIDRAP cidrap.umn.edu/antimicrobial…
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"We need to examine this issue and find ways to invest in the development of new antibiotics in order to give doctors and patients the tools that they need. This is a priority not just for the health of our people, but also for our national security." Thank you @SenatorHassan for brining attention to the rising threat of #AMR during yesterday's hearing. finance.senate.gov/hearings/…
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AMR Action Fund retweeted
Antimicrobial resistance is a growing public health threat that demands action. Thank you @SenatorHassan for your leadership and for recognizing the importance of investing in new antibiotics so physicians can continue providing lifesaving care. #PASTEURAct
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NDM-producing bacteria are rising rapidly in the U.S., threatening the effectiveness of some of our most important last-line antibiotics. A timely & important look at a growing clinical challenge from @CIDRAP #AMR cidrap.umn.edu/antimicrobial…
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Prosthetic joint infections can be devastating for patients and place a significant economic burden on healthcare systems. Current estimates suggest the cost of managing a single prosthetic joint infection can exceed $400,000, creating substantial challenges for hospitals, payers, and patients alike. As populations age and the number of joint replacement procedures continues to grow, the need for new treatment options is becoming increasingly urgent. That's why we're pleased to support Trellis Bioscience as it advances calpurbatug, an investigational monoclonal antibody, through Phase 2 clinical testing for PJIs. Learn more about our newest portfolio company: lnkd.in/eJXCPa7X #AMR
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“The Senate’s introduction of the PASTEUR Act of 2026 is a critical step toward rekindling private investment in one of the most essential yet neglected fields of medicine,” said Henry Skinner, PhD, CEO of the AMR Action Fund.
More than 2.8 million antibiotic-resistant infections occur yearly in the U.S. The bipartisan reintroduction of the #PASTEURAct would help address the broken antimicrobial marketplace and ensure patients have access to lifesaving treatments. bennet.senate.gov/2026/06/24…
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The PASTEUR Act "aims to stimulate private investment while preserving stewardship, and it has support among doctors’ groups like the Infectious Disease Society of America and industry groups like the Biotechnology Innovation Organization." thehill.com/opinion/healthca… #AMR
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We commend Sens. Michael Bennet, Todd Young, Kirsten Gillibrand, Mike Rounds, and John Hickenlooper for introducing the PASTEUR Act today. Their commitment to advancing market-based solutions reflects a growing recognition that addressing the rising threat of #AMR requires innovative policy approaches that meet public health needs. More info: bennet.senate.gov/2026/06/24…
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AMR Action Fund retweeted
We’re pleased to announce the topline data from our Phase 3 study conducted in collaboration with Shionogi & Co. in patients with invasive fungal disease. Visit our website to view our press release: f2g.com/media/ FOR INVESTORS & JOURNALISTS ONLY
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"Nearly 70% of the K pneumoniae isolates, which were primarily from women over age 60 with UTIs treated in outpatient settings, were nonsusceptible to the oral antibiotics routinely used to treat UTIs" #AMR via @CIDRAP cidrap.umn.edu/antimicrobial…
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In EU, reported cases of gonorrhea have increased 303% since 2015, along with a spike in cases of congenital syphilis via @cidrap cidrap.umn.edu/sexually-tran…
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