Assistant Professor of Medicine @bu_bmc_renal @BUMedicine| Nephrologist @BU_Amyloidosis |Patient care | Research | Education | Associate Editor @asnpublications
Boston Medical Center
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Thrilled to share our new publication in the @NEJM nejm.org/doi/full/10.1056/NE…
"Trends and Prevalence of Chronic Kidney Disease in the United States" led by @SophieClaudel @bu_bmc_renal @The_BMC @BUMedicine @ASNKidney @AHAScience @goKDIGO
CKD prevalence in the U.S. hasn't changed in a decade — from 14.5% in 2013 to 14.8% in 2023 — affecting ~36 million adults.
But the disease underneath has changed: diabetes-linked CKD is up 29%, and heart failure now rivals diabetes as the strongest comorbid risk factor.
New in @NEJM 🧵
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Ashish Verma, MD retweeted
Shaping the next generation of kidney researchers, Sushrut S. Waikar, MD, MPH, has earned a Distinguished Mentor Award for his dedication to mentoring future leaders in nephrology. #ASNKidneyNews @waikarss
kidney.pub/KN1811-05
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Ashish Verma, MD retweeted
In #ChronicKidneyDisease, the urinary albumin creatinine ratio and urinary protein creatinine ratio provided clinically similar risk prediction for kidney and cardiovascular outcomes in a large cohort with established disease.
Although the urinary albumin-creatinine ratio was more strongly associated with kidney failure statistically, it did not provide meaningfully better discrimination, reclassification, or decision support than the urinary protein-creatinine ratio.
ja.ma/47p22C3
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Delighted to share our new publication
“Phenotypes of diabetic kidney disease and cardiovascular outcomes” @SophieClaudel @bu_bmc_renal @ASrivastavaMD @PBjornstadMD @BUMedicine @EJIM_journal @waikarss
kwnsfk27.r.eu-west-1.awstrac…
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Ashish Verma, MD retweeted
In #ChronicKidneyDisease, the urinary albumin creatinine ratio and urinary protein creatinine ratio provided clinically similar risk prediction for kidney and cardiovascular outcomes in a large cohort with established disease.
Although the urinary albumin-creatinine ratio was more strongly associated with kidney failure statistically, it did not provide meaningfully better discrimination, reclassification, or decision support than the urinary protein-creatinine ratio.
ja.ma/4xRC6Ka
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Ashish Verma, MD retweeted
In #ChronicKidneyDisease, the urinary albumin creatinine ratio and urinary protein creatinine ratio provided clinically similar risk prediction for kidney and cardiovascular outcomes in a large cohort with established disease.
Although the urinary albumin-creatinine ratio was more strongly associated with kidney failure statistically, it did not provide meaningfully better discrimination, reclassification, or decision support than the urinary protein-creatinine ratio.
ja.ma/4rr3IUP
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Ashish Verma, MD retweeted
In #ChronicKidneyDisease, the urinary albumin creatinine ratio and urinary protein creatinine ratio provided clinically similar risk prediction for kidney and cardiovascular outcomes in a large cohort with established disease.
Although the urinary albumin-creatinine ratio was more strongly associated with kidney failure statistically, it did not provide meaningfully better discrimination, reclassification, or decision support than the urinary protein-creatinine ratio.
ja.ma/4hLcqsH
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New in @JAMA_current : "Prediction Utility of Urinary Albumin-Creatinine vs Protein-Creatinine Ratios in Chronic Kidney Disease"
jamanetwork.com/journals/jam… @waikarss @SophieClaudel @bu_bmc_renal @The_BMC @BUMedicine
🧵👇
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Result: net benefit curves for base + UACR and base + UPCR were superimposable.
The markers differed by ≤3 net correct decisions per 1000 in the focus zones, with a maximum of 9.4/1000 anywhere. Both are well below our prespecified 20/1000 margin.
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Ashish Verma, MD retweeted
Joint Impact of Aldosterone and Low-Density Lipoprotein Cholesterol on Cardiovascular Risk in CKD
bit.ly/4A2iUvt
@AnandVaidya17
ALT Restricted cubic spline plota,b,c,d of the association of serum aldosterone with major cardiovascular events (MACE) across levels of low-density lipoprotein (LDL) in persons with CKD and without baseline cardiovascular disease aThe plot depicts the hazard ratio for each doubling of serum aldosterone across varying levels of LDL. Hazard ratios are calculated using LDL = 70 mg/dL as the reference. The solid line represents the estimated hazard ratio, while the shaded area indicates the 95% confidence interval.
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Delighted to share our manuscript “Joint Impact of Aldosterone and Low-Density Lipoprotein Cholesterol on Cardiovascular Risk in CKD - American Journal of Kidney Diseases” ajkd.org/article/S0272-6386%… @AJKDonline @AnandVaidya17 @waikarss @The_BMC @bu_bmc_renal @BUMedicine
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Ashish Verma, MD retweeted
Key takeaways on CKD prevalence, according to @BUMedicine data:
🗝️ ~36 million U.S. adults have CKD
🗝️ Diabetes-associated CKD has significantly increased
🗝️ More patients met criteria for CKD from albuminuria presence vs. low eGFR
Learn more @GoHealio
vist.ly/5dhdc
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