Daily intriguing images from global research. Supported by @LeicaMicro & @BiochemOxford. bpodaily.bsky.social SO MUCH MORE & LINKS on bpod.org.uk

Oxford
Whole in One: Expansion microscopy + machine learning combined in WHOLISTIC – a means to image networks of cellular activity body wide 📹 Virginie M. S. Ruetten et al @HHMIJanelia in @Nature ➡️ bpod.org.uk/archive/2026/10/… with @DrJohnAnkers
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In fruit flies, the cell death enzyme caspase Dcp1 can also promote tissue growth under the regulation of autophagy-Bruce protein axis 📷 @ACaspaseLover et al @UTokyo_News_en in @eLife ➡️ bpod.org.uk/archive/2026/10/…
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Quick Dish: Sub-second 3D printing by digital incoherent synthesis of holographic light fields (DISH) could revolutionise tissue engineering 📹 Xukang Wang, Yuanzhu Ma, Yihan Niu et al @Tsinghua_China in @NatureComms ➡️ bpod.org.uk/archive/2026/10/… with @DrJohnAnkers
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How allergic inflammation engages sensory neurons => debilitating effects incl. pain in the food allergy response eosinophilic oesophagitis 📹 @KKellermanUCCOM et al @CincyChildrens in @NatureComms ➡️ bpod.org.uk/archive/2026/10/…
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Early life gut infection triggers an immune response that delays development & colonisation by 'friendly' bacteria as the microbiota–gut–brain axis is disrupted 📷 Jungjae Park et al @ucdavis in @PNASNews ➡️ bpod.org.uk/archive/2026/10/… with @DrJohnAnkers
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Biomedical Picture of the Day BPoD retweeted
How do cells turn stored fats into energy? Researchers combined single-shot STED-FLIM imaging, lipid dyes & deep learning analysis to visualize the endoplasmic reticulum, mitochondria & lipid droplets in living cells. See more: fcld.ly/nh9il8z @BPoD_s @BiochemOxford
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Eye on Fat: The complex process across organelle membranes that results in energy production from lipids captured in live cells using @LeicaMicro microscopy 📸 Lu Gao & Beibei Gao et al @sjtu1896 in @ScienceAdvances ➡️ bpod.org.uk/archive/2026/10/…
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Spheroid with cells derived from human induced pluripotent stem cells + myelin-producing oligodendrocytes to study myelin regeneration + screen drugs 📹 Shwathy Ramesan et al University of Melbourne in @NatureNeuro ➡️ bpod.org.uk/archive/2026/10/…
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Role of Fat: Lipids in DNA organisation revealed in chlamydia infection – associated host sphingolipids are released before bacterial DNA condensation 📹 Marcel Rühling & Fabienne Wagner et al Julius-Maximilians-University Würzburg in @NatureComms ➡️ bpod.org.uk/archive/2026/10/…
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Double Blow: Link revealed between the gene loss causing Prader-Willi syndrome & placental blood vessel development 📸 Anna E. Webberley & Raquel Boque-Sastre et al @cardiffuni in @DMM_Journal ➡️ bpod.org.uk/archive/2026/10/… with @AntDLewis
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Taxanes' cancer cell-inhibiting activity & possibly their side-effects result from them altering conformation of microtubule lattices 📹 @psychescope & Varsha Mahapatra et al @UniUtrecht in @NatureCellBio ➡️ bpod.org.uk/archive/2026/10/…
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Campylobacter concisus key culprit for intestinal disorder environmental enteric dysfunction passes down generations – microbiome targeting may treat 📸 Alexandra Byrne; Kali M. Pruss & Clara Kao et al @WUSTLnews in @NatureMicrobiol ➡️ bpod.org.uk/archive/2026/10/… with @rooph
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Alzheimer's-associated gene variant APOE4 promotes change of pericytes to myofibroblasts in the brain due to a raise TGF-β signalling => vessel fibrosis + plaques 📸 @BraxtonSchuldt et al @IcahnMountSinai in @CellCellPress ➡️ bpod.org.uk/archive/2026/10/…
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Assembloids of thalamic & cortical brain stem cells  reveal radial glia need physical connection with thalamic neurons to mature 📸Claudia Nguyen et al @BhaduriLab @UCLA in @ScienceMagazine ➡️ bpod.org.uk/archive/2026/10/… with @rooph
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Epithelium adapts to circs 'flowing' or behaving as a solid sheet: jamming of cell fluidity is regulated by metabolic changes triggered by cell crowding 📹 Alexandra Bermudez & Zoe Latham et al @UCLA in @PNASNews ➡️ bpod.org.uk/archive/2026/10/…
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Smart microscope platform PyCLM controls stimulation & imaging of tissues – showcased with optogenetic controlled EGFR to direct tissue movement 📹 Harrison R. Oatman et al @toettch lab @Princeton in @CellPressNews Cell Systems ➡️ bpod.org.uk/archive/2026/10/… with @AntDLewis
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Age Related: Secretory proteins modulate over C.elegans life - ACP7 (we have similar) increases with age & boosting it extended worm lifespan 📸 @JayJWM50 et al @BrunetLab @Stanford in @CellReports ➡️ bpod.org.uk/archive/2026/10/…
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Neuron detail over a wide field using @LeicaMicro 's Viventis Scape microscope 📹 by Dr Nick Gatford @KavliOxford made in the @MicronOxford facility ➡️ Read more on bpod.org.uk/archive/2026/10/… with @DrJohnAnkers
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Bidirectional organisation of actomyosin network drives invagination & shaping study in sea squirt Ciona shows – insights for tube & lumen development 📸 Jinghan Qiao & Pengyu Yu et al, Ocean University of China & @Tsinghua_Uni in @eLife ➡️ bpod.org.uk/archive/2026/10/…
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Windows on Windows: Super-Resolution Optical Sectioning Microscopy allows blood vessel pores to be examined in situ 📸 Jasmin C. Schürstedt-Seher et al Biomolecular Photonics, Faculty of Physics, Bielefeld University in @biorxivpreprint ➡️ bpod.org.uk/archive/2026/10/… + @AntDLewis
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