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Anti-PF4/heparin and anti-PF4 antibodies can cooperate to induce platelet activation, thrombocytopenia, and thrombus formation. ow.ly/9EBB50WfHp6#thrombosisandhemostasis
High-risk RUNX1 and STAG2, but not low-risk TET2, mutations selectively expand different compartments of SF3B1-mutant primitive HSPCs. ow.ly/uhFl50WfHnv#myeloidneoplasia
miR-150-5p acts as tumor suppressor by repressing the lymphomagenic-driver E2F3, leading to cell cycle disruption in PBL. ow.ly/fXmr50WfH2e#lymphoidneoplasia
Zanubrutinib demonstrated reduced risk of progression/death compared to ibrutinib, acalabrutinib, and bendamustine or idelalisib+rituximab. ow.ly/HtOG50WfGUG#lymphoidneoplasia
A comparison between interventions that will be sought by providers and patients undergoing intervention requires uniform assessments that evaluate disease- and intervention-related effects for informed decision-making. ow.ly/45Or50WfGmr#healthservicesandoutcomes
Venous thromboembolism, which includes deep vein thrombosis and pulmonary embolism, represents a complex pathological process extending far beyond inflammatory mechanisms. ow.ly/mJTu50WfG1P#thrombosisandhemostasis
Congenital or hereditary thrombotic thrombocytopenic purpura is a rare autosomal recessive disease caused by biallelic severe defects in the ADAMTS13 gene, either homozygous or compound heterozygous. ow.ly/K1gM50WfFY5#thrombosisandhemostasis