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Ribo-ITP enables ribosome occupancy measurements from single cells. Our first application revealed insights into allele-specific ribosome engagement in early development (nature.com/articles/s41586-0…). #RiboITP #singlecell
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Cenik Lab retweeted
Earlier this summer I came across this and recommended to a new student in the lab: courses.ibiology.org/catalog…
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In our new preprint, we integrated three multiplexed assays of variant effect to profile several layers of gene expression for thousands of variants in COMT! biorxiv.org/content/10.1101/…
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Ribo-ITP enables ribosome occupancy measurements from single cells. Our first application revealed insights into allele-specific ribosome engagement in early development (nature.com/articles/s41586-0…). #RiboITP #singlecell
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Through collaborations, we're applying Ribo-ITP to diverse areas like early mouse limb development, brain organoids, immune cells, and rare cancer cells. If you are interested in adopting Ribo-ITP, here is our step-by-step protocol with video instructions: ceniklab.github.io/ribo_itp/
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Cenik Lab retweeted
We are happy to unveil our latest published work where we describe how the metabolic enzyme, Pyruvate Kinase (PKM), regulates global mRNA translation in human cells. Here's a short 🧵... academic.oup.com/nar/advance…
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Cenik Lab retweeted
Our study showing that Hedgehog signaling is essential for maintaining the early foregut and larynx by preventing EMT was published: doi.org/10.7554/eLife.77055 @eLife. This was led by recent @UTexasILS graduate Janani Ramachandran with help from Hongkai Ji @jihk99 and @ZornLab.
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Cenik Lab retweeted
Congratulations to the 2022 @UT_iGEM team for winning the the Best Foundational Advance award at the iGEM Grand Jamboree! They were also a top 10 overall undergraduate team, finalists for Best Presentation and Best Part Collection, and awarded a Gold Medal. @ut_mbs @TexasScience
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Cenik Lab retweeted
Our 1st effort into dissecting the crosstalk between #autophagy & other vacuolar trafficking pathways, now out in @JCellBiol Thx to everyone involved!
‼️ #JustPublished in @JCellBiol
New work from the Dagdas Lab at GMI @PlantoPhagy sheds light on the mechanism of #autophagosome maturation in #plants 🌱🌿
Read more: ➡️ bit.ly/PlantAmphisome
#autophagy #plantautophagy #plantorganelle #organelletrafficking #amphisome
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Hypodermal ribosome synthesis inhibition induces a nutrition-uncoupled organism-wide growth quiescence in C. elegans biorxiv.org/content/10.1101/… @SarinayElif
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Cenik Lab retweeted
🌮BioTACOS tomorrow, Mon Oct 17, 2022 9:30 am- 🌮
"RiboBase: A comprehensive databse of ribosome profiling data" by Hakan Ozadam in @CenikLab
Please join in!
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Cenik Lab retweeted
It was our pleasure to host @SarinayElif for a virtual seminar today. Thanks a lot Elif for showing us the wonders of C.elegans and sharing your most recent findings with us.
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Cenik Lab retweeted
The MEF boss himself, @LabVokes , demonstrates the secrets and arts of MEF derivation!
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We had a great time at #RNA2022. Lots of exciting talks including from @SarinayElif and @Jamie_Yelland. Looking forward to watching the recorded talks that we missed during the meeting.
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Cenik Lab retweeted
Our latest work on HIV-1 translation: Extensive uORF translation from HIV-1 transcripts conditions DDX3 dependency for expression of main ORFs and elicits specific T cell immune responses in infected individuals biorxiv.org/content/10.1101/…
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Cenik Lab retweeted
Cell autonomous and non-autonomous consequences of deviations in translation machinery on organism growth and the connecting signalling pathways dlvr.it/SPK6Cl
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