Professor and Chair of Stanford Biology using systems approaches to discover Ca2+ signaling by the calcineurin phosphatase. #phosphatase #PhosphatasePhanatics
Stanford, CA
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Thank you to #ECS2024 for establishing the Claude Klee memorial lecture and inviting me to deliver this keynote. Great way to celebrate Claude Klee’s legacy and talk about calcineurin!
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Great work! Congratulations @DaveyLab @Ivarssonlab @NilssonLabCph
Our new paper with the @Ivarssonlab &
@NilssonLabCph teams
characterising mutations in intrinsically disordered regions on a proteome-wide scale! We show numerous examples of disease-causing SNVs making and breaking SLiMs in work driven by Johanna Kliche. embopress.org/doi/full/10.10…
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Martha Cyert retweeted
Available projects for #ESPOD interdisciplinary #postdoc fellowships between the @sangerinstitute and @emblebi! Join mine and Bayraktar group using spatial technologies and modelling to study the microenvironment regulation of glioblastoma (Project 3). ebi.ac.uk/research/postdocs/…
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Congratulations!
Congratulations to the winners of our 2023 @J_Cell_Sci paper prize! The quality of the shortlisted papers was so high that our Editors decided to award three prizes this year, so take a bow @StephenMCoscia, @eirinit94 and Rachel Wills.
journals.biologists.com/jcs/…
ALT Stephen Coscia (left), Eirini Tsekitsidou (middle) and Rachel Wills (right)
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Martha Cyert retweeted
Excited to announce the next #ECSwebinar on June 5th - 5 PM CET!🌟
We are looking forward to the talk of David Yule on modulation of IP3R regulation by Ca2+.
Find meeting link and updates on upcoming webinars here: docs.google.com/spreadsheets…
@DavidYule64
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Wow! What an inspiring story of a life with motifs! Thank you Toby for the impact on my science as well as so many others’.
Toby Gibson retired from EMBL after 38 years here – mostly spent as a team leader, collaborating to build and apply key tools used widely among life scientists.
Looking back, he supplied stories & insights into what he’s learned along the way. #EMBL50
embl.org/news/people-perspec…
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Si wonderful to see this great scientist’s work highlighted!
Mary Lyon FRS was born #OnThisDay in 1925. Lyon was the discoverer of X-chromosome inactivation, which the genetic process that leads to coloration like tortoiseshell cats. Read more about her discoveries in a new @RSocPublishing biographical memoir: royalsocietypublishing.org/d…
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Great work. Congratulations!
We are proud and excited to share the new study from our lab, led by the amazing @RanenAviner. It uncovers an important pathogenic mechanism causing cellular dysfunction in Huntington's Disease. We hope this work will inspire new and effective therapies
nature.com/articles/s41556-0…
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See our new preprint on biorxiv: unique functions for composite LxVp IxIT motif in a calcineurin scaffold and substrate. Thrilled to be working with Hari Arthanari lab! Congrats to Devin and Joana first authors.
A novel motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin biorxiv.org/cgi/content/shor… #biorxiv_biochem
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Martha Cyert retweeted
9 days left! Any questions feel free to DM or email me.
Amazing #postdoc position alert in our group @emblebi! Funded by @OpenTargets , collaboration with the @Garnettlab @sangerinstitute and industry partners. We have produced the largest dataset to date of dual CRISPR perturbations (65K pairs, 45 cell lines, 2 tissue types) and are
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Martha Cyert retweeted
4/4 In an illustration of their relationship to PTMs, molecular glues mimic a modification that recruits degradation machinery.
(See the Perspective for additional insights into and examples of proximity-inducing compounds.)
(See original post here: nitter.siddz.com/arenabioworks/status/1…)
1/4 A new Perspective by @SchreiberStuart proposes a new way of thinking about #molecularglues in terms of their relationship to missense mutations enshrined by natural selection and posttranslational modifications (PTMs) that are often found in hotspots. chemrxiv.org/engage/chemrxiv…
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Excited to be giving the Claude Klee memorial lecture at upcoming European Calcium Society meeting. See you there!
Registration is OPEN!🎈
We're excited to join the #ECS2024 meeting in Cambridge on 31 Aug - 4 Sept 🥳
Fantastic programme and possibilities to present both in talks or with posters.
More info here:
cambridge2024.calciumsociety…
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Very excited that our paper received 'best paper of 2023' prize! Congratulations to @eirinit94 and thanks to our co-author and awesome mentor @jenntrosome and collaborators @gingraslab1 @StearnsLab.
Find out more about the research from first author Eirini Tsekitsidou (@eirinit94): journals.biologists.com/jcs/…
ALT Ultrastructure expansion microscopy of centrosomes in a quiescent, ciliated hTERT-RPE1 cell (left) and a mitotic hTERT-RPE1 cell (right)
ALT Eirini Tsekitsidou
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Martha Cyert retweeted
This week we're excited to welcome @StachowiakLab and @DavidWSanders2 to our first IDPSeminar of 2024! Zoom info has been sent out - if you're missing it just run through our registration form forms.gle/3yCHeYvuuqLhDgef6 for direct access!
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Congratulations @Bertolotti_lab on this beautiful work!
Phosphatase study solves substrate recruitment puzzle mrc-lmb.cam.ac.uk/phosphatas…
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Martha Cyert retweeted
February 1st marks the beginning of Black History Month – a time to reflect on the innumerable contributions Black people have made to society and acknowledge their invaluable role in American history.
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fabulous work!
Congrats to all on a fabulous collaboration between the Yule and Patel labs exploring cross-talk in calcium signaling between lysosomes and endoplasmic reticulum.
cell.com/cell-reports/pdf/S2…
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Martha Cyert retweeted
🚨The updated version of our ultralow background membrane editor story (❤️ those LOVPLDs!) is now published @ACSCentSci!
🎉🎉🎉 to @JuliaXL_Li @MasaakiU5 @ReikaTei @weillinstitute @CornellChem #lipidtime #optogenetics
pubs.acs.org/doi/10.1021/acs…
Our latest membrane editors just dropped — bravo to @JuliaXL_Li who led this study w/@ReikaTei & @MasaakiU5! To learn about how they accomplished this feat of protein engineering and optogenetics, and why it is cool and important, see thread below: 1/n
doi.org/10.1101/2023.08.31.5…
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