Matt DeJong@DejongMatt

PhD candidate in the @fordycelab and @Dunn_Lab studying ChemE at Stanford. Past member of the Hackel lab @UMNews. (he/him)

Joined April 2020
9 Photos and videos
First preprint of the @fordycelab and @Dunn_Lab collaboration! We used high-throughput microfluidics for sequence-strength mapping at the single-molecule level. Our new tech allowed us to discover a fundamental nonequilibrium property of multivalent systems. 1/13
3
21
68
21,263
Matt DeJong retweeted
Isaac Li@IsaacLiLab
Jun 22
Excited to share our Science Advances paper introducing Tether Force Spectroscopy: flow-stretched DNA "sails" that pull on molecules and read out single-molecule behaviour by fluorescence. No beads. Huge thanks to Adam, Ryan and the team. science.org/doi/10.1126/scia…
2
6
228
Matt DeJong retweeted
Polly Fordyce@fordycelab
Jun 3
Characterizing AI-designed proteins requires quantitative biochemistry at massive scale. Enter Amplicon/Protein Bead Display (APB-Display), a fully in vitro platform that quantifies Kd's for >100,000 variants in <3 days (preprint link below!) @Stanford_ChEMH @czbiohub (1/n)
3
95
440
64,445
Matt DeJong retweeted
Micah Olivas@MicahOlivas1
May 11
Many experiments in biology happen one protein at a time, which means synthesizing DNA one gene at a time. This is fine for tens of genes. For thousands, the cost is unsustainable. Introducing uSort-M: a method to isolate and sequence-verify thousands of genes at low cost
10
66
326
40,722
Matt DeJong retweeted
Polly Fordyce@fordycelab
Apr 3
New preprint alert - 5 years in the making! Using high-throughput microfluidic enzyme kinetics, we profiled 190 clinical variants of SHP2, a phosphatase linked to developmental disorders & cancer (1/8) biorxiv.org/content/10.64898… @Stanford_ChEMH, @czbiohub, @bioe_stanford
5
39
191
14,025
First preprint of the @fordycelab and @Dunn_Lab collaboration! We used high-throughput microfluidics for sequence-strength mapping at the single-molecule level. Our new tech allowed us to discover a fundamental nonequilibrium property of multivalent systems. 1/13
3
21
68
21,263
more replies
To learn more, you can find our new preprint here! 12/13 biorxiv.org/content/10.64898…
1
1
3
535
This work wouldn’t be possible without support of my thoughtful co-advisors @fordycelab and @Dunn_Lab , their creative labs, generous funders @StanfordBioX @NSF @NIH @Stanford_ChEMH @czbiohub , and my amazing co-authors! 13/13
1
2
3
837
Matt DeJong retweeted
Isaac Li@IsaacLiLab
12 Oct 2024
I am excited to share our latest work on creating the first tunable Catch-Bond with #DNA! Our Fish-Hook architecture allowed precise control of adhesion nanomechanics, creating new possibilities for bioengineering and material science! 🧬🐟🪝🌟nature.com/articles/s41467-0… #biophysics
5
14
30
2,354
Matt DeJong retweeted
Polly Fordyce@fordycelab
21 Aug 2024
Interested in intrinsically disordered proteins or transcription factor activation? Or purifying & measuring affinities for 1000s of protein/protein interactions? Check out @nicole_delrosso & Peter Suzuki's preprint (w/ @BintuLab & @alexholehouse) shorturl.at/jEneh (1/n)
3
60
208
21,786
🚨 JOB ALERT 🚨 Join our team at Velocity Bio and help us unlock new drug discovery paradigms! We're looking for a Senior R&D Scientist with deep expertise in NGS, Molecular Biology, and Python. Please 🔃 & spread the word! #hiring #sciencejobs jobs.ashbyhq.com/pear/d97b51…
5
17
1,849
Load more