Lung transplant and ICU physician | Basic and Translational Researcher | UCSF and SFVAMC | NK cell immunology
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Daniel Calabrese retweeted
did a dog write this
A surprising new study finds that people who sleep near their dogs don’t experience disrupted sleep. If anything, the University of Toronto researchers discovered, we humans are the ones disturbing our dogs’ sleep. nbcnews.com/health/health-ne…
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Plague is caused by a bacteria (Yersinia pestis), not a virus. But, who knows if this strain has been modified since it leaked from a lab….that 100 catch receiver potentially on HGH to continue the analogy
I feel like being this kind of virus is like being the 100 catch receiver on a 2-15 team, like sure respect and all, but end of the day we're not scared of you, you don't matter that much.
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Kidney injury hurts the lungs, and NK cells are part of the bridge. New in @AmJTransplant: depleting CD94+ NK cells protects both organs after IRI and improves survival after mouse kidney transplant. Fantastic work by Reena Bharti and team @UCSFDOM. sciencedirect.com/science/ar…
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Out in @ATSBlueEditor: severe PGD is linked to CMV reactivation and mortality in latent CMV+ donor lungs. Led by the terrific Marian Poley @UCSFDOM with our LTOG partners at @PennMedicine. First chapter of a bigger story, more to come. academic.oup.com/ajrccm/adva…
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Daniel Calabrese retweeted
ICYMI - A genetically modified pig kidney kept a man off dialysis for nine months before a successful human kidney transplant, according to a world-first report in The Lancet.
Read now: spkl.io/60167r8VE
ALT Figures showing (A) Total daily urine output (mL) during the first week after xenotransplantation. (B) Serum creatinine and eGFR throughout the xenograft period. Note that scales on y axes differ between plots. Vertical dashed lines indicate for-cause kidney biopsies\u2014key histopathological findings are annotated: day 14, Banff IIA TCMR; day 176, MVI with endothelial injury; day 264, TMA with transplant glomerulopathy. (C) Serum sodium. (D) Serum potassium. All panels share a common x-axis representing days relative to xenotransplantation (day 0). eGFR=estimated glomerular filtration rate. MVI=microvascular inflammation. TCMR=T-cell-mediated rejection. TMA=thrombotic microangiopathy. Copyright: 2026 Elsevier Ltd. All rights are reserved.
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⏰ Applications for 3️⃣ #ISHLTResearchGrants and the #InternationalVisitingScholarship are due in two weeks!⠀⠀⠀
📅 Submit by 30 September at 11:59 p.m. ET / 1 October at 03:59 UTC⠀
📖 View eligibility criteria + apply at 🔗 bit.ly/4650n53
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Daniel Calabrese retweeted
🚨 Editor’s Choice 🚨
"Tensor-based integration of time-series measurements reveals relationships between underlying disease, early injury, and T cell polarization in liver transplantation," by Chin et al
buff.ly/rn30EkO
#LiverTransplantation #TransplantImmunology
ALT Visual abstract to accompany article
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Wow. Didn’t think to use it for something like that. Almost a parable for these times sfchronicle.com/outdoors/art…
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#ISHLTResearchGrants can further your research career. 🔎💡 Join the ranks of past grant recipients by applying for one of the 3️⃣ open grants.
📅 You have until 30 September to apply!
#ISHLT #HeartTx #LungTx #Biomarkers #EVLP
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Daniel Calabrese retweeted
Proud to be a part of this group of co-authors articulating our approach to care for patients with Meth-Associated Pulmonary Arterial Hypertension.
The latest CHEST How I Do It article provides a practical approach to care for patients with methamphetamine-associated PAH that incorporates pharmacologic therapy in conjunction with harm reduction strategies.
Read more in the August issue of the journal CHEST®: hubs.la/Q04t3pm_0
#MedEd #JournalCHEST
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📢 A NEW #ISHLTConsensusStatement on Assessing and Addressing #Frailty in Candidates for #LungTransplantation is now available. 📖💡🫁 This document provides practical guidance on how to integrate frailty assessments into clinical practice.
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View the top 8️⃣ takeaways ⤵️
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Daniel Calabrese retweeted
A defining mark of #LungTransplant dysfunction: doi.org/10.1172/jci.insight.…
Chitaru Kurihara & team @NUFeinbergMed identify POSTN-positive fibroblasts as key contributors to fibrotic restrictive chronic lung allograft dysfunction after lung transplantation. Moreover, the presence of POSTN-positive fibroblasts distinguishes restrictive allograft syndrome from bronchiolitis obliterans syndrome, both of which lead to lung transplant dysfunction.
@AnkitBharatMD @miyasea1225
@NM_Lung @NorthwesternMed @NIHFunding
#PulmonaryFibrosis
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Daniel Calabrese retweeted
Laying down a data infrastructure can help facilitate novel collaborations and innovations, as Aartik Sarma, MD, @UCSF, explains on the ATS Breathe Easy podcast.
This research was part of the ATS ICU Pause program, which aims to educate health care providers, including trainees, intensivists, hospitalists, and advanced practice providers around patient safety and equity in diagnosis at the time of ICU discharge.
Watch the episode on ATS NOW or tune in wherever you listen to podcasts: atsnow.thoracic.org/media/55…
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The deadline to submit your abstracts to #ISHLT2027 closes earlier this year. ⏰ Have your science in the treatment of advanced #heart and #lung disease, #transplantation, #MCS, and #PVD presented on a global stage. 🫀🫁🌎
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Congratulations!
Congrats to @SumiRamendra on the successful defence of her PhD today @UofT_LMP. Sumi’s incisive work has uncovered novel roles for B cells in lung fibrosis. Bonus: the thesis was accepted without corrections! Well done Sumi!
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Of course. The superior outcomes that everyone (me included) tout from countries with universal or socialized healthcare get a bit complicated. The US private and public health R&D is 1/2-2/3 of global invested $. We also subsidize low drug prices elsewhere through our high costs
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Daniel Calabrese retweeted
The WSJ’s conservative editorial board takes President Trump to task for his vaccine EO, concluding: “Mr. Trump’s jab at children’s vaccines could alienate voters who are already souring on his second term. The other risk: more measles.” wsj.com/opinion/donald-trump…
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Gastric cancer incidence is 4-5 fold higher in East Asia which makes general screening programs (upper endoscopy) more cost effective and favorable from a risk vs benefit perspective. We are moving to risk stratified screening.
People frequently get details wrong on what health care problems the U.S has and don't understand that we are pretty fantastic at some aspects of it
Found this interesting nugget on where we are less good on cancer - unsurprisingly it's where you need screening consistency
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Daniel Calabrese retweeted
Frederick Sanger, born #onthisday in 1918, is one of only seven laureates to have received the #NobelPrize more than once.
ALT Black and white portrait of Frederick Sanger wearing a suit and tie.
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