1/12 With colleagues in 14 jurisdictions in 6 countries we have just published a study on the predictors and consequences of cancer diagnosis within 30 days after an emergency hospital admission (=emergency presentation) in @TheLancetOncol thelancet.com/pdfs/journals/… A🧵:

From measurement to improvement: new evidence on reducing emergency cancer diagnoses 🎯 Nearly 25% of cancer patients are diagnosed in emergency settings, and these patients face significantly worse outcomes, even after accounting for disease stage. A new editorial by @glyratzopoulos and colleagues discuss this finding and present a new taxonomy of evidence on diagnosis of cancer as an emergency Read the full editorial to learn how diagnostic process evaluation can drive meaningful improvements here: bit.ly/4b9hYei Read the original article by Khalaf et al here: bit.ly/4sJYH94

Older men with new-onset fatigue are relatively likely to have an undetected cancer, compared to other cohorts. Figure: 1-year disease risk in men bjgp.org/content/early/2024/… @BexKWhite @MattBarclay89 @Glyratzopoulos @UCL_BSH @UCL_IHI @BrianDNicholson @SpirosDenaxas @DrMeenaRafiq

Congratulations on winning one of the best posters @DrMeenaRafiq @RCGPAC #RCGPAC

Great to hear the primary care cancer OG tag team tell us about the early diagnosis of cancer @drtomround @SamMerriel @richarddneal Best4 trial: fundingawards.nihr.ac.uk/awa… Prostate cancer trial: prostatecanceruk.org/researc… MCED: mced.info/ #rcgpac

I’m thrilled to receive a @CRUKresearch International Alliance for Cancer Early Detection (ACED) - Pathway Award for the ICEBERG project 🧊: Improving Cancer Early detection using Blood tEst Results in General practice 🩸 📈 👩🏻‍⚕️ 🦠 @UCL_BSH @GLyratzopoulos @Cambridge_Uni

Nonspecific symptoms pose a diagnostic challenge to primary care cancer diagnosis and can result in repeat pre-diagnostic GP presentations. New interventions are needed to help pick up these cancers earlier. @drtomround #RCGPAC2024 @GLyratzopoulos

3/3  A third of EP patients were previously referred urgently; faster specialist assessment may have resulted in non-EP diagnosis in some. EP patients who were also emergency-referred had 9-fold higher mortality within a month post-diagnosis, compared to non-EP patients @CRUKHCPs

2/3 “Predictors and consequences of different pathways to emergency diagnosis of cancer in England: Evidence from linked national audit and cancer registration data" @RuthSwann, @GLyratzopoulos, @Gregrubin4, @EllissBrookes, Sean McPhail” @CancerEpid pubmed.ncbi.nlm.nih.gov/3916…

1/3 With colleagues @RuthSwann, @GLyratzopoulos, @Gregrubin4, @EllissBrookes, Sean McPhail we have recently published a study aiming to understand pathways to diagnosis of cancer as an emergency presentation, and their consequences, a bit more pubmed.ncbi.nlm.nih.gov/3916…

All adults will have 1 diagnostic error in their life. It was an honour to be the Keynote speaker at the @WHO #WorldPatientSafetyDay in Budapest presenting on how to improve diagnostic safety in primary care 👩🏻‍⚕️

Patients with as-yet-undetected cancer start using GP healthcare more several months before cancer diagnosis and blood tests may help to diagnose them earlier. @DrMeenaRafiq presents work from UK and Australia @CRUKHCPs #CRUKEDConference24 @UCL_BSH @VCCCAlliance

Day 2 of #CRUKEDconference24 showcases more work from @QMUL_CCSPED @Jo_WallerPhD @Suzanne_Scott_ and ends with two great sessions led by @Katriina01 and @GLyratzopoulos Great conference with so much thought provoking work!

"The ED may be involved in the initial identification of cancer for 1 in 5 #patients (65y+)". New findings from US #Medicare data analysis - closely following our work linked below, highlighting concerns for population #Health and #cancer academic.oup.com/jncics/adva… @GLyratzopoulos

"vaccination has averted 154 million deaths" On the 50th anniversary of WHO's Expanded Programme on Immunization, Naor Bar-Zeev & colleagues quantify the public health impact of vaccination: hubs.ly/Q02ymFn60

New commentary @LancetRH_WPac from international collaboration with @famednusg @josemvalderas Cross-country learning can lead to improved cancer diagnosis and outcomes for all. @QMUL_WIPH @QMUL_CCSPED @CanTest_PC doi.org/10.1016/j.lanwpc.202…

People living in deprived areas are more likely to receive a colon #cancer diagnosis through emergency hospitalisation. This study, published today in @BrJCancer, digs into the details of #inequality in cancer diagnosis. Read more on our website 👉 bit.ly/3QIbPv9

#Sexinequality in #bladdercancer diagnosis may be due to differences in #haematuria frequency and onset between men and women. @GLyratzopoulos @fmw22 @JianhuaWu6 @QMUL_WIPH @QMUL_CCSPED More in our new @BJUICompass paper: doi.org/10.1002/bco2.360

Guideline concordance for timely chest imaging after new presentations of dyspnoea or haemoptysis in primary care: a retrospective cohort study @mmkoo12 @LukeMounce @DrMeenaRafiq @CallisterMat @HardeepSinghMD @garyabel @glyratzopoulos thorax.bmj.com/content/79/3/…

Many congratulations @DrMeenaRafiq , onwards and upwards to even greater things!👏

It has been terrific to, alongside @MattBarclay89 and Cristina Renzi, contribute to this innovative work led by @BexKWhite as part of her @ucl PhD studies. Thank you @BJGPjournal for hosting, disseminating & including in the Journal's 'top-10' papers for 2023 🙏👏