In a phase 3 randomized clinical trial published in @JAMAInternalMed, #elinzanetant was assessed in postmenopausal women aged 40 to 65 years seeking treatment for moderate to severe #Menopause-associated vasomotor symptoms.
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Learn why JAMA Internal Medicine Associate Editor Tracy Wang, MD, selected this trial for @JAMAplusTrials as one of the most important clinical trials published last year:
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📌 How can clinicians and researchers stay up to date on the most clinically relevant trials?
@JAMAplusTrials highlights the implications and innovations of clinical trial research from across the JAMA Network: ja.ma/3V6Ri8J
How should extension studies to clinical trials be interpreted?
💭 Cast your vote in the latest JAMA+ Trials poll and share your perspective.
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Do extension studies to clinical trials increase participants’ motivation to enroll in the original trial?
Or should they be considered cohort studies, not trials in themselves?
📊 Cast your vote in the latest JAMA+ Trials Poll.
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What statement in our JAMA+ Trials poll best reflects your opinion on extension studies?
📊 Cast your vote on 1 of our 5 options in the latest JAMA+ Trials Poll and share your perspective.
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What’s your take on extension studies to clinical trials?
Do they provide longer-term insights, increase participants’ motivation to enroll in the original trial, or something else?
📊 Cast your vote in the latest JAMA+ Trials Poll.
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Presented at #ESMO26 from @JAMA_current:
In low erythroblastic oncogene B 2 (ERBB2) advanced #BreastCancer, trastuzumab rezetecan showed benefit in hormone receptor–positive and hormone receptor-negative disease.
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Presented at #ESMO26 from @JAMA_current: For low erythroblastic oncogene B 2 (ERBB2) advanced #BreastCancer, trastuzumab rezetecan improved progression-free survival vs chemotherapy in both chemotherapy-naive patients and the overall population.
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Finding relevant clinical trial evidence can be time-consuming.
JAMA+ Trials brings together nearly 3,000 curated trial reports published across the JAMA Network, making it easier to search, browse, and discover clinical trial research in one place.
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JAMA+ Trials brings together research, commentary, and educational content designed to help readers interpret and communicate trial evidence.
🔗 Explore the latest research and educational resources: ja.ma/3U6SU1V
Looking for trial evidence across specialties?
@JAMAplusTrials offers a searchable collection of recent trial reports published across the JAMA Network.
📚 Discover research, commentary, and educational content: ja.ma/4iyXeAf
🧵 How useful are "pragmatic" clinical trials for informing real-world decision-making?
In the latest @JAMAplusTrials poll, only 10.9% of respondents believed that nearly all trials labeled as "pragmatic" successfully provide useful evidence for real-world decisions.
🔖 This October's Trial Theme of the Month focuses on extension studies in #ClinicalTrials, where long-term findings depend on how comparison groups are defined and how attrition and selection bias are handled.
🔗 Read the latest editorial: ja.ma/4zqdoBD
🔖 JAMA+ Trials is a new platform that highlights the implications and innovations of #ClinicalTrial research from across the JAMA Network to advance evidence-based #medicine and public #health.
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💭 In your opinion, how many clinical trials that claim to be "pragmatic" are successful in providing useful evidence for real-world decision-making?
JAMA+ Trials wants to hear from you.
🔗 Share your perspective: ja.ma/4iMBSQB
📢 JAMA+ Trials wants to hear from you.
Share your perspective in our latest poll and help spark discussion around the future of clinical trial research.
📊 Vote now: ja.ma/3TniYWb
📢 Share your opinion: How many clinical trials that claim to be "pragmatic" actually provide useful evidence for real-world decision-making?
📊 Vote now and join the discussion: ja.ma/4h5U1rm#ClinicalTrials#Research#Evidence
How many clinical trials that claim to be "pragmatic" are successful in providing useful evidence for real-world decision-making?
💭 Cast your vote in the latest JAMA+ Trials Poll and share your perspective.
📊 Take the poll: ja.ma/4yMrE7l
💭 In your opinion, how many clinical trials that claim to be "pragmatic" are successful in providing useful evidence for real-world decision-making?
@JAMAplusTrials wants to hear from you.
🔗 Vote now: ja.ma/4hhDAHf