Highlighting the implications and innovations of clinical trial research to advance evidence-based medicine and public health.

In a phase 3 randomized clinical trial published in @JAMAInternalMed, #elinzanetant was assessed in postmenopausal women aged 40 to 65 years seeking treatment for moderate to severe #Menopause-associated vasomotor symptoms. ja.ma/4iTfCUz
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Learn why JAMA Internal Medicine Associate Editor Tracy Wang, MD, selected this trial for @JAMAplusTrials as one of the most important clinical trials published last year: ja.ma/4Ad6m3L
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📌 How can clinicians and researchers stay up to date on the most clinically relevant trials? @JAMAplusTrials highlights the implications and innovations of clinical trial research from across the JAMA Network: ja.ma/3V6Ri8J
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How should extension studies to clinical trials be interpreted? 💭 Cast your vote in the latest JAMA+ Trials poll and share your perspective. 📊 Take the poll: ja.ma/4ilvgH3
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Do extension studies to clinical trials increase participants’ motivation to enroll in the original trial? Or should they be considered cohort studies, not trials in themselves? 📊 Cast your vote in the latest JAMA+ Trials Poll. 🔗 Vote now: ja.ma/4yIkWiu
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What statement in our JAMA+ Trials poll best reflects your opinion on extension studies? 📊 Cast your vote on 1 of our 5 options in the latest JAMA+ Trials Poll and share your perspective. 🔗 Vote now: ja.ma/4yIkWiu
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What’s your take on extension studies to clinical trials? Do they provide longer-term insights, increase participants’ motivation to enroll in the original trial, or something else? 📊 Cast your vote in the latest JAMA+ Trials Poll. 🔗 Vote now: ja.ma/4yIkWiu
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Presented at #ESMO26 from @JAMA_current: In low erythroblastic oncogene B 2 (ERBB2) advanced #BreastCancer, trastuzumab rezetecan showed benefit in hormone receptor–positive and hormone receptor-negative disease. ja.ma/3W4qiH5
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Presented at #ESMO26 from @JAMA_current: For low erythroblastic oncogene B 2 (ERBB2) advanced #BreastCancer, trastuzumab rezetecan improved progression-free survival vs chemotherapy in both chemotherapy-naive patients and the overall population. ja.ma/4ievcIS
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Finding relevant clinical trial evidence can be time-consuming. JAMA+ Trials brings together nearly 3,000 curated trial reports published across the JAMA Network, making it easier to search, browse, and discover clinical trial research in one place. ja.ma/4iacmCL
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JAMA+ Trials brings together research, commentary, and educational content designed to help readers interpret and communicate trial evidence. 🔗 Explore the latest research and educational resources: ja.ma/3U6SU1V
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Looking for trial evidence across specialties? @JAMAplusTrials offers a searchable collection of recent trial reports published across the JAMA Network. 📚 Discover research, commentary, and educational content: ja.ma/4iyXeAf
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🧵 How useful are "pragmatic" clinical trials for informing real-world decision-making? In the latest @JAMAplusTrials poll, only 10.9% of respondents believed that nearly all trials labeled as "pragmatic" successfully provide useful evidence for real-world decisions.
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🔖 This October's Trial Theme of the Month focuses on extension studies in #ClinicalTrials, where long-term findings depend on how comparison groups are defined and how attrition and selection bias are handled. 🔗 Read the latest editorial: ja.ma/4zqdoBD
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🔖 JAMA+ Trials is a new platform that highlights the implications and innovations of #ClinicalTrial research from across the JAMA Network to advance evidence-based #medicine and public #health. 📬 Learn more and subscribe to the email newsletter: ja.ma/3VsMSsO
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💭 In your opinion, how many clinical trials that claim to be "pragmatic" are successful in providing useful evidence for real-world decision-making? JAMA+ Trials wants to hear from you. 🔗 Share your perspective: ja.ma/4iMBSQB
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📢 JAMA+ Trials wants to hear from you. Share your perspective in our latest poll and help spark discussion around the future of clinical trial research. 📊 Vote now: ja.ma/3TniYWb
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📢 Share your opinion: How many clinical trials that claim to be "pragmatic" actually provide useful evidence for real-world decision-making? 📊 Vote now and join the discussion: ja.ma/4h5U1rm #ClinicalTrials #Research #Evidence
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How many clinical trials that claim to be "pragmatic" are successful in providing useful evidence for real-world decision-making? 💭 Cast your vote in the latest JAMA+ Trials Poll and share your perspective. 📊 Take the poll: ja.ma/4yMrE7l
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💭 In your opinion, how many clinical trials that claim to be "pragmatic" are successful in providing useful evidence for real-world decision-making? @JAMAplusTrials wants to hear from you. 🔗 Vote now: ja.ma/4hhDAHf
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