The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms

The Physiological Society
In this study, Angelina Rogliardo (@INM_Montpellier) and collaborators observed that deletion of the sodium leak channel #NALCN in #dopamine neurons alters D2R-mediated signalling and psychostimulant responsiveness 🧠 Read the #research👇️ buff.ly/gwZ6TWM
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'The first brain at the centre: An enteric reframing of the nervous system' Tim Hibberd (@Flinders) and co-authors present this #Opinion article discussing the recent work of Barboi and Macefield in renaming the autonomic nervous system 💭 💡 buff.ly/9ZugLY8
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Journal of Physiology retweeted
Dr. Aaron Grossberg's research on #PancreaticCancer cachexia and its relationship with cardiac dysfunction was published in @JPhysiol and received Editor's Choice honors for August! Learn more: bit.ly/4dSs3ND
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'Beyond CO2 reactivity: The integrated role of systemic circulation in exercise-induced cerebral blood flow responses' Shigehiko Ogoh (@Toyo_Univ_PR) highlights the recent work of Simpson et al. (2026) in this #Perspective article ✍️ 💭 Read it here: buff.ly/C5aZum9
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Featuring on the cover of the latest issue, Emmet A. Francis (@UCSDPharm) and colleagues observed that interplay between store-operated #calcium entry and #mitochondrial phosphate handling modulates force and #fatigue during exercise 🔬 🚴 🔗 📜 buff.ly/F6h6ngJ
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'When does sweating change during puberty? Revisiting the developmental timing of sex differences in sweating capacity' Read this recent #JournalClub by KarLee Lefebvre (@ICMtl) and co-authors, examining the work of Topham et al. (2026) ✍️ 🎓️ 🔗 buff.ly/6iutwRe
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In this study, Lili Salinas (@ucdavisbiology) and collaborators examine #mitochondrial dynamics and repair differences in two mouse models of Friedreich's #ataxia 🔬 🫀 Read the findings👇️ buff.ly/PKhfvcM
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A. K. Guzmán-Aguayo (@InstitutoPluri) & colleagues observed that early #kidney injury occurs in the absence of detectable perirenal adipose tissue remodelling in the Munich Wistar Frömter rat model of chronic kidney disease💉 🔬 Read the #research👇️ buff.ly/JdmNejR
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Lydia L. Simpson (@uniinnsbruck) and collaborators investigated the mechanisms regulating #cerebral perfusion during running #exercise and the influence of foot strike-induced pulsatility oscillations, CO2 reactivity and BP ⚙️ 🏃‍➡️ Read the study: 🔗 buff.ly/3sSbJra
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Joelina Lienau (@UCPH_health) presents this #JournalClub titled 'Uncovering strategies to rescue muscle mass in ageing' which examines the work of Carvalho et al. (2026) ✍️ 👇️ 🔗 buff.ly/OoMEi5G
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William Bechtel (@UCSanDiego) and Leonardo Bich (@upvehu) present this #TopicalReview: 'The last-step integrator thesis: Heterarchical control of the mammalian gastrointestinal tract' 📜 💡 Read it here👇️ buff.ly/wVfGIIL
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Using a maximal elastance analysis, #research by Cheng-Yuan Lai and co-investigators finds that #myostatin-dependent detrusor remodelling mediates contractility impairment in #diabetic rats’ bladder 🔬 🔎 Read the article: buff.ly/JTtllAt
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K. K. Lange (@UCPH_health) and collaborators examined the effects of #exercise followed by a low-carbohydrate diet on peak fat oxidation and #mitochondrial coupling control and efficiency in healthy trained men 🔎 🚴 Read the findings👇️ buff.ly/VzWiq74
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'The ageing #kidney remembers its nutritional beginnings'💭 Kieran M. Short and John F. Bertram (@MonashUni) offer this #Perspective on the recent study by Pires et al., (2026) ✍️ Read it here👇️ buff.ly/RM6jEvZ
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'Metabolism meets modulation: Lactate's redox-driven control of NMDARs' Cullan Voelkner (@BrockFAHS) and co-authors examine the recent study by Fiumelli et al. (2026) in this #JournalClub article🎓️ ✍️ 🔗 buff.ly/NC9rbZy
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🎓️ EDITOR'S CHOICE🎓️ Pereira Pires and colleagues show that early malnutrition of the fetus shifts the #renal proteome towards mitochondrial/redox metabolism and is accompanied by histopathological lesions in the kidney🔬 Read the article💡 buff.ly/cIcdpNE
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Latest issue now live🎉 The cover image comes from the work of Francis et al. and depicts model predictions of peak contractile force during the final repetition of a resistance training set 📸 Read all articles here📖 buff.ly/fgDQpSE
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In this study, Sophia T. Jenz (@NUPTHMS) and collaborators observed that #motor unit discharge properties are modestly influenced by #menstrual cycle–related fluctuations in sex #hormone concentrations 📆 🔎 Read it here👇️ buff.ly/k6LFmxu
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#Research by Tamzin Zawadzki (@uni_copenhagen) and colleagues finds that slow #calcium removal contributes to impaired #lusitropic response to β-adrenergic stimulation in HFpEF mice 🫀 🔬 Read the article here👇️ buff.ly/AY39w2E
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Celebrating 100 years of the Chinese Association for Physiological Sciences (CAPS) 🎓️ 🎉 Yun Wang (@PKU1898) and colleagues discuss the pivotal role of CAPS in building physiology in China in this editorial 📜 Read it here👇️ buff.ly/hdHMnHP
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