Out now in @ESC_Journals from #HFC member @JavedButler1 et al. This study evaluates the prognostic significance of residual moderate secondary mitral regurgitation in patients with heart failure after optimization of guideline-directed medical therapy. doi.org/10.1093/eschf/xvag25…

What if biomarker, functional and MACE outcomes are nested in one integrated cardiometabolic clinical trial design, without upsetting the alpha police? Thank you @FaiezZANNAD, @JavedButler1, @ArunJSanyalVCU for an excellent #MOSAICMASH in DC!

Body Composition in Heart Failure: A Magnetic Resonance Imaging and Dual X-Ray Absorptiometry Assessment in the UK Biobank Study. doi.org/10.1016/j.jchf.2026.… Contributions from Baim faculty, @ambarish4786 and @JavedButler1. #BaimInstitute #ClinicalResearch #Cardiology

Screening and Treatment Using a Risk-Based Approach With NT-proBNP Guidance in Diabetes Mellitus: The STRONG-DM Pilot Study. doi.org/10.1016/j.jchf.2026.… Contributions from Baim faculty, @ambarish4786 and @JavedButler1. #BaimInstitute #ClinicalResearch #DM

Defining Clinically Meaningful Within-Patient Changes in Heart Failure: JACC: Heart Failure Position Statement. doi.org/10.1016/j.jchf.2026.… Contributions from Baim CSO, James Januzzi, and Baim faculty, @JavedButler1. #BaimInstitute #ClinicalResearch #HeartFailure

Albuminuria and heart failure. doi.org/10.1093/eurheartj/eh… Contributions from Baim faculty, @JavedButler1. #BaimInstitute #ClinicalResearch #Cardiology #HeartFailure

Prof. Javed Butler makes the case for upstream #NLRP3 inhibition: targeting inflammasome activation closer to plaque-level danger signalling may matter for residual inflammatory risk. Watch the video here: rezera.com/perspective/the-c…

Optimal implementation of SGLT2i to the 57.5 million US adults with T2DM, HF or CKD: 🫀 ~362,000 fewer HF 🏨/year ✅ ~224,000 deaths prevented/year 💰 $24.9 billion net savings/year 📈 ~$10 back per $1 spent (generic pricing) #SGLT2i more than pays for itself

Albuminuria and heart failure UACR AND HEART FAILURE: A CARDIORENAL WARNING SIGNAL Albuminuria is more than a marker of kidney damage. It is an independent predictor of incident and worsening heart failure, hospitalization and mortality. 📊 Key messages: 🔹 HF risk rises progressively with increasing UACR—even at low levels of albuminuria. 🔹 Across multiple studies, albuminuria is associated with approximately 1.5- to 6-fold higher HF risk, depending on the population and UACR level. 🔹 Its prognostic value extends beyond kidney disease, including in patients with diabetes and atrial fibrillation. 🔹 UACR is a simple, accessible biomarker that can improve cardiorenal risk stratification. 💡 Clinical takeaway: Don’t wait for eGFR to decline. Measure UACR to identify patients at increased cardiovascular and HF risk—and act early. #HeartFailure #Cardiorenal #Albuminuria #CKD #Cardiology #Nephrology #UACR #CardiovascularPrevention @JavedButler1 @mvaduganathan @gcfmd @SJGreene_md @GianluSava @HFA_President @hfcollaboratory academic.oup.com/eurheartj/a…

🫀 Of 243,510 patients with newly diagnosed HF: only 15.4% started an sMRA 😳 
📉 HFrEF 29.6% | HFmrEF 14.0% | HFpEF 9.5% 
🩺 Lowest uptake: HFpEF, yet <1 in 3 in HFrEF 
⏱️ Median 10 days to start 
🔗 doi.org/10.1016/j.cardfail.2…
 @HFSA #HFSA2026

Honored to present the VESALIUS-CV CABG analyses as a late breaker today at EACTS. @GilbertTangMD @DLBHATTMD @JavedButler1 @UnityHealthTO @cscs_sccc @UofTSurgery @UofTCVsurgery

Great overview on current state of GDMT in HF by @ambarish4786 at #proCardioForum. @markcpetrie20 @lamcardio @loridanielsmd @mvaduganathan @JavedButler1 @gcfmd

>100,000 of these HF deaths each year could have been readily prevented @HFSA @JCardFail

2026 iCARDIO Alliance Global Implementation Guidelines on Heart Failure. doi.org/10.1016/j.cardfail.2… Contributions from Baim CSO, Dr. James Januzzi and Baim faculty, @hvanspall, @DrMarthaGulati, and @JavedButler1. #BaimInstitute #Cardiology #HeartFailure

Thank you Dr Fonarow, Thank you Dr Gulati, Dr Butler🙏

Disease modification outcomes in type 2 diabetes: a modified Delphi. doi.org/10.1016/s2213-8587(2… Contributions from Baim faculty, @JavedButler1 and Dr. Leigh Perreault. #BaimInstitute #ClinicalResearch #T2D

Another important JACC:HF Position Statement: Defining Clinically Meaningful Within-Patient Changes in HF @AminYehyaMD @hahn_rt @VDelgadoGarcia @noshreza @mpsotka @JJheart_doc @totocarbone @JavedButler1 @NatalieTapaskar @AndrewPAmbrosy jacc.org/doi/epdf/10.1016/j.…

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Out now in @JACCJournals from #HFC members @tremartyn @JavedButler1 @BiykemB et al. This study analyzes trends in mortality, readmission, and home time after HF hospitalization from 2016–2022, including differences by race and Medicare plan type. jacc.org/doi/10.1016/j.jchf.…