Here is an interesting quote from practicalfragments.blogpsot.… : "By far the biggest winner among methods has been X-ray crystallography; it jumped from sixth place in 2011 to first place in both 2019 and 2024." Yeah!
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Where to House Big Data on Small Fragments? | ChemRxiv - go.shr.lc/4j3oXY1
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Manfred S. Weiss retweeted
Publications aplenty. 2024 abounded in reviews related to FBLD - structure-based methods, covalent fragment strategies, targets, PROTACs, and more
practicalfragments.blogspot.…
@sa_poulsen @ManfredSWeiss @ACSPublications @nmr900 @DiamondLightSou
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Manfred S. Weiss retweeted
Just published in @Structure_CP: A review with contributions from @ManfredSWeiss, detailing the challenges, state-of-the-art and future directions for integrated structural biology at European research infrastructure sites.
doi.org/10.1016/j.str.2024.0…
@HZBde @HZB_BESSY @instructhub
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Manfred S. Weiss retweeted
Exiting news: a new publication describing the HZB-MX F2X fragment-screening facility in all aspects is out in @Appl_Research. Read all about our facility here:
onlinelibrary.wiley.com/doi/…
Congratulations to @TatjanaBKL, Melanie and the entire F2X-team.
@HZBde @HZB_BESSY
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Manfred S. Weiss retweeted
Out now in @ActaCrystD : A new paper with contributions from @ManfredSWeiss, about crystallographic fragment screening against a protein from Mycobacterium tuberculosis. Read all about it here:
doi.org/10.1107/S20597983240…
@HZB_BESSY @HZBde
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Manfred S. Weiss retweeted
Hot off the press: a new paper in the European Journal of Medicinal Chemistry, with contributions from @ManfredSWeiss. Read all about the structure-based mapping of the KDM4D binding pocket here:
doi.org/10.1016/j.ejmech.202…
@HZBde @HZB_BESSY @ELSchemistry
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Manfred S. Weiss retweeted
@ManfredSWeiss will be attending the ACA conference in Denver next week.
Anybody interested in IUCr-2029 can approach him and get the latest news.
@IUCr2023 @DGK @JKYC_DGK
@Swisscrystallog
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Manfred S. Weiss retweeted
🔔Meeting support available for #EarlyCareerScience
Early registration & bursary application deadline for the International School on Fundamental Crystallography 7th MaThCryst School in Latin America >>
24 June 2024!
even3.com.pe/e/ISFC2024-7Mat…
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Manfred S. Weiss retweeted
🗓️We've updated our logo and our calendar! For more information please refer to the @IUCr website where you can find out about bursaries, abstract deadlines and registration ↓ iucr.org/calendar/calendar-o…
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Manfred S. Weiss retweeted
Hot of the press in @ChemMedChem: A new paper with contributions from @ManfredSWeiss and @Jan_Wollenhaupt, featuring data collected at BL 14.2. It describes new Furin inhibitors partly based on fragments, even making front cover!
doi.org/10.1002/cmdc.2024000…
@HZBde @HZB_BESSY
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Manfred S. Weiss retweeted
Out now, in @ActaCrystD: A new paper from Neumann et al, with contributions from @Jan_Wollenhaupt and @ManfredSWeiss. Read all about it here:
doi.org/10.1107/S20597983240…
@HZB_BESSY @HZBde
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Manfred S. Weiss retweeted
The #DGKconference in beautiful sunny Bayreuth had 4 days of informative lectures interspersed with fun social evenings bringing people from diverse fields together, ending successfully with a interview with @IUCr by @florian_meurer (Our new Chair🥳) and Tina Weigel (ex-Chair❤️)
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Manfred S. Weiss retweeted
Save the date:
Wednesday, 24. 04 is the monthly Colloquium by Zoom, organized by @AfSynchrotron (4PM GMT+2)
"The problem of protein folding: how it may go wrong and how cellular machines make it go right" by Paolo De Los Rios from @EPFL_en
Registration: us02web.zoom.us/meeting/regi…
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Manfred S. Weiss retweeted
Everybody, please stop by and pick up your IUCr-2029 badge @Conventus_Jena
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