𝗙𝗼𝘂𝗿 𝗱𝗮𝘆𝘀 𝗹𝗲𝗳𝘁 𝘁𝗼 𝗮𝗽𝗽𝗹𝘆 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗦𝗨𝗥𝗙𝗘²𝗥 𝗡𝟭 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗚𝗿𝗮𝗻𝘁 Are you working on electrogenic membrane transporters? The SURFE²R N1 grant offers the selected recipient: ✔️ A SURFE²R N1 in their lab for six months ✔️ Full training on the system ✔️ Consumables ✔️ Expert assay development support Applications are open to researchers worldwide and close this 𝗙𝗿𝗶𝗱𝗮𝘆, 𝗢𝗰𝘁𝗼𝗯𝗲𝗿 𝟭𝟲, 𝟮𝟬𝟮𝟲. Learn more and access the application form 👇 ow.ly/JcSX50ZWNM2 #MembraneTransport #TransporterResearch #Electrophysiology #ResearchGrant

𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝗰𝗲𝗹𝗹 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻 𝗹𝗶𝘃𝗲 𝗮𝘁 𝘁𝗵𝗲 𝗡𝗮𝗻𝗶𝗼𝗻 𝗨𝘀𝗲𝗿 𝗠𝗲𝗲𝘁𝗶𝗻𝗴 𝟮𝟬𝟮𝟲 Join our Cell Analytics Workshop to explore what different cellular readouts can tell you about your experiments. We will look at impedance measurements with AtlaZ, as well as contractility and extracellular field potentials with CardioExcyte 96. Using cardiomyocytes as a shared model, we will investigate responses to selected compounds and discuss how complementary measurements can support the interpretation of cellular responses. 📅 October 20, 2026 🕙 09:45–12:00 CEST 📍 Nanion Headquarters | Munich, Germany Participation is free, but places are limited. Reserve your place: ow.ly/HaqO50ZT38p #CellAnalytics #Impedance #CardioExcyte #AtlaZ #CellBasedAssays #DrugDiscovery

𝗪𝗵𝗮𝘁 𝗶𝗳 𝘆𝗼𝘂 𝗰𝗼𝘂𝗹𝗱 𝗳𝗼𝗹𝗹𝗼𝘄 𝘆𝗼𝘂𝗿 𝗰𝗲𝗹𝗹𝘀 𝗮𝘀 𝘁𝗵𝗲𝘆 𝗿𝗲𝘀𝗽𝗼𝗻𝗱, 𝗶𝗻 𝗿𝗲𝗮𝗹 𝘁𝗶𝗺𝗲? See how cells respond over time, including response kinetics, without labels or complicated workflows. The AtlaZ Research Grant is here for 2026. This grant is designed for researchers working with cellular models who want to better understand how their cells respond, change, and behave over time. AtlaZ can support projects studying cell health, compound effects, cytotoxicity, barrier function, morphology-related changes, or assay development. The selected researcher will receive an AtlaZ system in their lab for 6 months, including training, consumables, and expert application support. Interested in applying? Learn more about the application process here: ow.ly/5EGC50ZQW6Z 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗱𝗲𝗮𝗱𝗹𝗶𝗻𝗲: 𝗗𝗲𝗰𝗲𝗺𝗯𝗲𝗿 𝟮𝟬, 𝟮𝟬𝟮𝟲 #CellBiology #CellBasedAssays #DrugDiscovery #AtlaZ #Impedance

𝗚𝗣𝗖𝗥 𝗖𝗲𝗹𝗹 𝗔𝗻𝗮𝗹𝘆𝘁𝗶𝗰𝘀 𝗪𝗼𝗿𝗸𝘀𝗵𝗼𝗽 Are you staying in Montreal for one more day after SPS? Join us at McGill University for a focused workshop on GPCR research and real-time cell analytics with the AtlaZ system. The session will explore impedance-based assays and how label-free, real-time measurements can be used to follow cellular responses over time, including cell activity, viability, and connectivity. We’re very pleased to be joined by Prof. Terence Hébert and Prof. Joachim Wegener for the workshop. 📅 September 24, 2026 🕥 10:30–12:30 📍 McGill University, McIntyre Medical Sciences Building, Room 1345 If you’re attending SPS, staying in Montreal afterwards, or based around McGill University, we’d be happy to have you join us. Places are limited, so make sure to reserve your spot. Register for the workshop: ow.ly/aZt050ZIKa5 #GPCR #CellAnalytics #AtlaZ #SPS2026 #DrugDiscovery

Want to test different transporter substrates without developing a new assay every time? In 2024, Chloé Martens, PhD., received the SURFE²R N1 Research Grant, giving her group at the Université libre de Bruxelles the opportunity to work with the system. Many of the transporters they study interact with multiple substrates. When transport results in a net movement of electrical charge, SURFE²R N1 records the activity directly. This allows researchers to compare substrates, inhibitors and different conditions to explore how this affects transporter function. As Chloé explains: “Being able to screen different substrates without having to develop a completely new transport assay every time is a major advantage.” 𝗜𝗻 𝟮𝟬𝟮𝟲, 𝘁𝗵𝗲 𝗦𝗨𝗥𝗙𝗘²𝗥 𝗡𝟭 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗚𝗿𝗮𝗻𝘁 𝗶𝘀 𝗯𝗮𝗰𝗸. The selected recipient will have access to a SURFE²R N1 in their lab for six months, together with full training, consumables and expert assay development support. Could six months with the system support your transporter research? Applications are open to researchers worldwide until October 16, 2026. Learn more and apply: ow.ly/csnF50ZIbNo #MembraneTransport #TransporterResearch #Electrophysiology #ResearchGrant #SURFE2RN1

From ion channel research idea to patch clamp data Do you have a research question that could benefit from electrophysiology data? The Patchlinerᵐ Research Grant is open for scientists worldwide working on ion channel biology, membrane biophysics, target validation, assay development, and related research areas. Patchlinerᵐ offers a simpler way of doing patch clamp, helping researchers record multiple cells simultaneously while staying in control of their experiments. The selected grant recipient will receive: ✔️ Patchlinerᵐ in their lab for 6 months ✔️ Training ✔️ Consumables ✔️ Expert application support 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗰𝗹𝗼𝘀𝗲 𝗦𝗲𝗽𝘁𝗲𝗺𝗯𝗲𝗿 𝟮𝟱, 𝟮𝟬𝟮𝟲. Download the application form and submit your application on time: ow.ly/h35v50ZG28W #PatchClamp #Electrophysiology #IonChannels #IonChannelResearch #APC

𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗮𝗿𝗲 𝗻𝗼𝘄 𝗼𝗽𝗲𝗻 𝗳𝗼𝗿 𝘁𝗵𝗲 𝟮𝟬𝟮𝟲 𝗦𝗨𝗥𝗙𝗘²𝗥 𝗡𝟭 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗚𝗿𝗮𝗻𝘁 If you are studying electrogenic membrane transporters and need sensitive, real-time functional measurements, this opportunity could help move your project forward. The grant includes: ✔️ A SURFE²R N1 in your lab for six months ✔️ Full training on the system ✔️ Consumables for your research project ✔️ Expert assay development and scientific support Applications are open to researchers worldwide 𝘂𝗻𝘁𝗶𝗹 𝗢𝗰𝘁𝗼𝗯𝗲𝗿 𝟭𝟲, 𝟮𝟬𝟮𝟲. Could your project benefit from direct functional measurements of electrogenic transporters? Learn more and download the application form: ow.ly/C72b50ZzRhs #MembraneTransport #TransporterResearch #Electrophysiology #ResearchGrant

𝗧𝘄𝗼 𝗱𝗮𝘆𝘀 𝗼𝗳 𝘀𝗰𝗶𝗲𝗻𝗰𝗲, 𝗮𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀, 𝗮𝗻𝗱 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝗶𝗻𝗴 𝗶𝗻 𝗠𝘂𝗻𝗶𝗰𝗵 At the 𝗡𝗮𝗻𝗶𝗼𝗻 𝗨𝘀𝗲𝗿 𝗠𝗲𝗲𝘁𝗶𝗻𝗴 𝟮𝟬𝟮𝟲, researchers from academia and industry will share real-world applications across electrophysiology, membrane transport, cell physiology, disease-relevant models, and drug discovery. It is a space to learn from scientific talks, exchange ideas with peers, and see how functional data can support real research questions. 📅 October 20–21, 2026 📍 Munich, Germany 💻 In-person and online participation available Registration is open. Join us in Munich or online. ow.ly/oGOr50ZzomG Which topic would you like to see discussed at this year’s User Meeting? #Electrophysiology #PatchClamp #IonChannels #MembraneTransporters #CellAnalytics #DrugDiscovery

What does the Patchlinerᵐ Research Grant include? The selected recipient will receive: ✔️ Patchlinerᵐ in their lab for 6 months ✔️ Full training on the system ✔️ Consumables to support the research project ✔️ Expert assay and application support from Nanion’s electrophysiology specialists The grant is designed to support researchers exploring ion channel biology, biophysics, target validation, or assay development with a simpler way of doing patch clamp. Applications are open now and close September 25, 2026. Download the application form and apply here: ow.ly/6nCL50Zl7oj #PatchClamp #Electrophysiology #IonChannels #IonChannelResearch #APC

From organelle preparation to functional data, now available on demand Thank you to everyone who joined our webinar with ORIA Bioscience on Advances in High-Throughput Organellar Electrophysiology. Whether you missed the live session or would like to revisit the talks, the recording is now available. Bastien Masson and Markus Rapedius present complementary approaches spanning organelle preparation and high-throughput electrophysiology in native lysosomes, with applications in ion channel research and early drug discovery. Topics include: ✅ Streamlining organelle preparation workflows ✅ Native lysosome electrophysiology ✅ Reproducible, high-throughput measurements ✅ Applications in early drug discovery Access the recording here: ow.ly/taTb50Zw2Z5 #Electrophysiology #PatchClamp #Lysosomes #DrugDiscovery #OrganelleBiology

𝗥𝗲𝗴𝗶𝘀𝘁𝗿𝗮𝘁𝗶𝗼𝗻 𝗶𝘀 𝗼𝗽𝗲𝗻 𝗳𝗼𝗿 𝗠𝗣𝗦 𝟮𝟬𝟮𝟳 Planning ahead for next spring? The Membrane Physiology Symposium (MPS) 2027 is moving to the edge of the Pacific for two days of scientific exchange, discussion, networking, and the latest advances in membrane physiology. 📅 April 15–16, 2027 📍 Scripps Research Auditorium, San Diego, CA The speaker lineup is already available to explore on the registration page, bringing together researchers from across membrane physiology, ion channels, transporters, electrophysiology, and related fields. Registration is now open👇 ow.ly/Qqk450ZvKRu Will we see you in San Diego? #MembranePhysiology #IonChannels #MembraneTransporters #Electrophysiology #PatchClamp #DrugDiscovery #MPS2027

Could six months of instrument access move your membrane transporter research forward? The SURFE²R N1 Research Grant is back for 2026. The selected recipient will receive: ✔️ A SURFE²R N1 in their lab for six months ✔️ Consumables for their research project ✔️ Assay development and scientific support from our team Applications open on August 17. Interested in applying? Register your interest to receive the grant details and application timeline. ow.ly/cn7w50Zwfh3 #MembraneTransport #TransporterResearch #Electrophysiology #ResearchGrant

𝗣𝗮𝘁𝗰𝗵 𝗰𝗹𝗮𝗺𝗽 𝗺𝗮𝗱𝗲 𝘀𝗶𝗺𝗽𝗹𝗲. Researchers studying ion channels, membrane proteins, target validation, or assay development often rely on functional data to move their projects forward. But conventional patch clamp can be difficult to access without the right equipment, time, or specialist support. That is where the Patchlinerᵐ Research Grant comes in. The selected recipient will receive: ✔️ Patchlinerᵐ in their lab for 6 months ✔️ Full training ✔️ Consumables ✔️ Expert application support Patchlinerᵐ offers a simpler way of doing patch clamp, helping researchers record multiple cells simultaneously while staying in control of their experiments. 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗰𝗹𝗼𝘀𝗲 𝗦𝗲𝗽𝘁𝗲𝗺𝗯𝗲𝗿 𝟮𝟱, 𝟮𝟬𝟮𝟲. Apply here: ow.ly/RBpt50ZtLbQ #PatchClamp #Electrophysiology #IonChannels #IonChannelResearch #APC

𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗮𝗿𝗲 𝗻𝗼𝘄 𝗼𝗽𝗲𝗻! The first 𝗣𝗮𝘁𝗰𝗵𝗹𝗶𝗻𝗲𝗿ᵐ 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗚𝗿𝗮𝗻𝘁 is open for applications. If you have an ion channel, target validation, or assay development project that could benefit from patch clamp data, this is your opportunity to apply. The selected recipient will receive: ✔️ Patchlinerᵐ in their lab for 6 months ✔️ Full training ✔️ Consumables for the research project ✔️ Expert assay and application support Patchlinerᵐ offers a simpler way of doing patch clamp, helping researchers generate data from multiple cells simultaneously while staying in control of their experiments. Download the application form and submit by 𝗦𝗲𝗽𝘁𝗲𝗺𝗯𝗲𝗿 𝟮𝟱, 𝟮𝟬𝟮𝟲 Apply here: ow.ly/Y9MI50ZiLh4 #PatchClamp #Electrophysiology #IonChannels #IonChannelResearch #APC

𝗧𝗵𝗲 𝗳𝗶𝗿𝘀𝘁 𝗣𝗮𝘁𝗰𝗵𝗹𝗶𝗻𝗲𝗿ᵐ 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗚𝗿𝗮𝗻𝘁 𝗶𝘀 𝗵𝗲𝗿𝗲! What if patch clamp could be fast and simple, while keeping you fully in control? Many ion channel experiments are delayed by limited access to patch clamp equipment, resources, or expertise. Patchlinerᵐ offers a simpler way of doing patch clamp, helping researchers accelerate experiments and record multiple cells simultaneously. This grant is designed to help researchers explore ion channel biology, biophysics, target validation, and assay development. The selected recipient will receive: ✔️ Patchlinerᵐ in their lab for 6 months ✔️ Full training ✔️ Consumables for the research project ✔️ Expert assay and application support 🗓️ 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗼𝗽𝗲𝗻: July 2026 Want to be the first to receive updates about the grant? 𝗥𝗲𝗴𝗶𝘀𝘁𝗲𝗿 𝘆𝗼𝘂𝗿 𝗶𝗻𝘁𝗲𝗿𝗲𝘀𝘁 𝘁𝗼𝗱𝗮𝘆: ow.ly/wVPk50YYWoy #PatchClamp #Electrophysiology #IonChannels #APC

𝗙𝗼𝗿 𝗻𝗔𝗖𝗵𝗥 α𝟳, 𝘁𝗶𝗺𝗶𝗻𝗴 𝗺𝗮𝘁𝘁𝗲𝗿𝘀 Studying this fast-desensitizing nicotinic acetylcholine receptor requires precise ligand application, especially when capturing rapid activation kinetics. In this study, we show how fast ligand addition on the SyncroPatch 384, combined with HEK cells expressing nAChR α7/ric3, supports reliable pharmacological characterization. Key findings: ✅ Reproducible ACh-evoked currents ✅ Consistent EC₅₀ values for acetylcholine and nicotine ✅ Robust MLA inhibition and PNU-120596 potentiation With our neuroscience symposium taking place next week, this is a timely example of how assay design can help address challenging neuronal ion channel targets. Read more in the application note: ow.ly/HF0850YY91v #IonChannels #PatchClamp #APC #Electrophysiology #Neuroscience #DrugDiscovery #nAChR

𝗙𝗿𝗼𝗺 𝗴𝗲𝗻𝗲𝘁𝗶𝗰 𝘃𝗮𝗿𝗶𝗮𝗻𝘁𝘀 𝘁𝗼 𝗻𝗲𝘂𝗿𝗼𝗻𝗮𝗹 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻. How do we connect the dots? The full agenda for the 𝗡𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝟮𝟬𝟮𝟲 is now available. Across two sessions, researchers will explore how ion channels and transporters contribute to neurological dysfunction, from molecular mechanisms to functional electrophysiology in human neuronal models. Topics include: ▪️ Channelopathies and genotype–phenotype relationships ▪️ Transporters and emerging neurological targets ▪️ Functional interpretation of ion channel variants ▪️ Electrophysiology in human neuronal models The program brings together perspectives across neuroscience, electrophysiology, and membrane biology, highlighting how functional approaches can help bridge genetic variation to disease mechanisms. 📅 May 20, 2026 | 🌐 Free virtual event 👉 Explore the agenda & register: ow.ly/P18K50YVAIb #Neuroscience #Electrophysiology #IonChannels #MembraneTransporters #DrugDiscovery

𝗛𝗼𝘄 𝗱𝗼 𝘆𝗼𝘂 𝗿𝗲𝗹𝗶𝗮𝗯𝗹𝘆 𝗺𝗲𝗮𝘀𝘂𝗿𝗲 𝗳𝗮𝘀𝘁 𝗹𝗶𝗴𝗮𝗻𝗱-𝗴𝗮𝘁𝗲𝗱 𝗶𝗼𝗻 𝗰𝗵𝗮𝗻𝗻𝗲𝗹 𝗮𝗰𝘁𝗶𝘃𝗮𝘁𝗶𝗼𝗻? Nicotinic acetylcholine receptors (nAChRs) mediate fast synaptic transmission at neuromuscular junctions and are key targets in neuromuscular research. In this application note, we investigated nAChR (α1β1γδ) activation in TE671 cells using Patchlinerᵉ, focusing on rapid ligand application and reproducible pharmacology. The data show: ✔️ Reliable activation with acetylcholine (ACh) ✔️ EC₅₀ = 4.2 ± 0.3 µM, consistent with literature ✔️ Controlled ligand exposure (~175 ms) for reproducible measurements Precise solution exchange, combined with automated workflows, supports robust investigation of ligand-gated ion channels. Read the full application note here: ow.ly/oV2w50YREjh #Electrophysiology #PatchClamp #AutomatedPatchClamp #IonChannels #Neuroscience #DrugDiscovery

Two days of discussion, exchange, and membrane physiology at MPS 2026 To everyone who joined us (whether for the first time or as part of the growing MPS community), thank you for contributing to the exchange that defines this meeting. Some highlights from this year’s symposium: ▪️ Dr. Ardem Patapoutian highlighting the role of Piezo channels in mechanosensory biology, including a memorable explanation of how mechanosensation works, with a fitting analogy to tasting wine ▪️ Dr. Lori L. Isom on gene-modifying approaches for Dravet syndrome, a powerful reminder of the progress being made in rare disease research ▪️ High-quality poster sessions and discussions that continued beyond the talks We were inspired by the science shared and by the community that continues to shape MPS. Special thanks to our sponsors: Anatomic , Axol, 3Brain, Elements, Maxwell Biosystems, and Oria Bioscience. What was your highlight from MPS 2026? #MembranePhysiology #ScientificCommunity #MPS2026 #APC #MembraneBiophysics #CellAnalytics

What does it look like to measure ion channels in lysosomes with automated patch clamp? In this video, we show how native lysosomes can be functionally recorded using high-throughput automated patch clamp on the SyncroPatch 384. The workflow uses ready-to-use LYSO-Preps from ORIA Bioscience. From sample handling to automated recordings and data acquisition, this approach enables functional measurements across hundreds of lysosomes in parallel. ✅ Real-time temperature modulation ✅ Intraluminal or extraluminal pH changes during the experiment ✅ Ion channel pharmacology All within a controlled and scalable experimental setup. What would you explore if you could generate this kind of data at scale? #Lysosomes #Electrophysiology #DrugDiscovery #OrganelleResearch #HighThroughput #SyncroPatch384