Organic Chemistry Frontiers is an international high impact journal for cutting-edge researches from all disciplines of organic chemistry | 2023 IF - 4.6
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👉Check out recent #research: Synergistic catalytic allenylic alkylation for #stereodivergent construction of allenes bearing 1,3-axial and central chirality by Xiaohua Liu's team.
🔗doi.org/10.1039/D5QO00467E
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🔓#OpenAccess #metalcatalyst
Read 1,2 Wagner–Meerwein shift in aza-Nazarov cyclization: Bi(iii)-catalyzed substrate-dependent divergent synthesis of highly substituted pyrroles and indenes by Rishikesh Narayan's team.
🔗doi.org/10.1039/D5QO00168D
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👉Check out recent #review: Polyfluorinated reagents for peptide stapling, which focused on three major classes of polyfluorinated reagents: #rylation, #vinylation, and #amidation reagents.
🔗doi.org/10.1039/D5QO00112A
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🔓#OpenAccess #HAT #SET
Check out #research: Beyond HAT: harnessing TBADT for photocatalyzed Giese-type C(sp³)–C(sp³) bond formation through reductive decarboxylation by Maurizio Fagnoni et al. @unipv
🔗doi.org/10.1039/D5QO00399G
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🔥Recent #research by EiC Shengming Ma's team: Copper-catalyzed aerobic oxidation of aldehydes to carboxylic acids, in which an aerobic #oxidation of #aldehydes to #carboxylic acids using O₂ or air as the oxidant has been developed.
🔗doi.org/10.1039/D5QO00330J
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👉Check out recent #research Conformational preference of N-difluoromethylated amides: contributions of hydrogen-bonding, #steric, and #stereoelectronic effects by Ryu Yamasaki et al. @spu_kouhou
🔗doi.org/10.1039/D5QO00497G
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👉Read the #review regarding the #oxetane core #tolerance towards the reaction conditions of the typical toolbox:
Oxetane as a part of modern medicinal chemistry toolbox: the advanced synthesis of 3,3-disubstituted building blocks
🔗doi.org/10.1039/D5QO00572H
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👉Read recent #research meta-Selective thiofluoroalkylation of substituted pyridines via Zincke imines table by @willcdhartley, Omar Boutureira et al. @universitatURV
🔗doi.org/10.1039/D5QO00533G
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Back cover of Issue 11 showcases research from Bappaditya Gole 𝘦𝘵 𝘢𝘭.
"Unveiling stereoselective ladders viaphoto-oligomerization of a diazaanthracene macrocycle"
#Free_to_read
🔗 doi.org/10.1039/D5QO00159E
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Inside cover of Issue 11 presents
"Palladium-catalyzed chemoselective decarboxylative coupling of alkynyl carboxylic acids with halogenated aryl triflates" by Chau Ming So 𝘦𝘵 𝘢𝘭.
#Free_to_read
🔗 doi.org/10.1039/D5QO00339C
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🔔Issue 11 is available! Please read the cover article:
"Supramolecular catalysis in the dearomative Michael addition involving nitro-group-activated benzofurans" by Anna Skrzyńska, Łukasz Albrecht 𝘦𝘵 𝘢𝘭.
#Free_to_read
🔗doi.org/10.1039/D5QO00035A
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👉Recent #research clarifies the synergistic roles of Ni and Al: Mechanistic insights into Ni–Al co-catalyzed alkyne carbophosphination enabled by C–P bond activation by Congcong Huang, Yishi Lia and Juan Li. @jnu1906
🔗doi.org/10.1039/D5QO00453E
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🔥A #hot #review article by @huangx513's team: Recent advances in repurposing natural enzymes for new-to-nature asymmetric #photobiotransformations, which is also included in the Emerging Investigator Series #EMI of OCF.
🔗doi.org/10.1039/D5QO00470E
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📢Don't miss our CCS-RSC Young Chemist webinar! Meet with Dr. Agnieszka Nowak-Król, Early career advisory board member of Organic Chemistry Frontiers, and other young scientists!
⏰Time: 7:00 am (UK time)
📅Date: May 30, 2025
👉Register here: rsc.zoom.us/webinar/register…
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👉Read #review article Advancements and perspectives toward radical Truce–Smiles-type rearrangement by Yuxi Wang, Chao Shu et al.
🔗doi.org/10.1039/D5QO00360A
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🔥Read #hot #review article regarding: Visible light-mediated #halofunctionalization of alkenes for the synthesis of vicinally functionalized organohalides. By Kanta Pajujantaro, Ying Chena and Gong-Qing Liu. #NTU
🔗doi.org/10.1039/D5QO00439J
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🔥Recent #hot article: Enantioselective catalytic Urech hydantoin synthesis by Yu-Ping He's team, in which an example of asymmetric catalytic UHS is disclosed. Check it out if you are interested!
🔗doi.org/10.1039/D5QO00378D
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🔥Check out this #hot #review article, which is also included in our 10th anniversary collection: Photo and earth-abundant metal dual catalysis in organic synthesis by Zhan Lu's team.
#photocatalysis #metalcatalysts
🔗doi.org/10.1039/D5QO00102A
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🔓#OpenAccess #Vinylfluorides #Palladium
Read recent #research Palladium-catalysed regio- and stereo-controlled C-2 β-fluorovinylation of indoles by Atul K. Chaturvedi and Alastair J. J. Lennox. @BristolUni
🔗doi.org/10.1039/D5QO00521C
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🔓#OpenAccess #palladium #decarboxylation
Read Palladium-catalyzed chemoselective decarboxylative coupling of alkynyl carboxylic acids with halogenated aryl triflates by Chau Ming So's team. @HongKongPolyU
🔗doi.org/10.1039/D5QO00339C
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👉Read recent #research Monofluoromethylation of acyl chlorides and chloroformates employing fluorobis(phenylsulfonyl)methane. Synthesis of monofluoromethyl ketones via selective zinc-mediated reductive desulfonylation by G. K. Surya Prakash' team.
🔗doi.org/10.1039/D5QO00451A
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Back cover of Issue 10
"A DFT investigation of the mechanism of photoinduced radical borylation of alkyl bromides: elucidation of base-mediated photoinduced SET and S៷2 processes"
#Free_to_read
🔗 doi.org/10.1039/D5QO00048C
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Issue 10 is available! Please read the cover article:
"Protodefluorinated Selectfluor® heteroaggregate photoinduces direct C(sp³)–H fluorinations without photocatalyst" by Shahboz Yakubov and Joshua P. Barham.
#Free_to_read
🔗doi.org/10.1039/D5QO00149H
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🔥Read the #research Copper-catalyzed radical transnitrilation of arylborons with dimethylmalononitrile and mechanistic insights by Xiaofu Jian, Xibao Zhang and Weilong Xie. #DHU
#Aromaticnitriles #radicalpathway
🔗doi.org/10.1039/D5QO00397K
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🔓#OpenAccess #paracyclophane
Take a look at [2.2]Paracyclophane-substituted quinolines by skeletal editing strategies by Tilman Köhler, Olaf Fuhr and @StefanBraese. @KITKarlsruhe
🔗doi.org/10.1039/D5QO00505A
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👉Check out recent #research by @yuzhouleilei's team: Acidic pH-modulated photoswitching of sulfur-bridged seven-membered cyclic azopyridines. @SCUCN
#photoswitches #DBTD
🔗doi.org/10.1039/D5QO00315F
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👉Have you read the #research article Machine learning-guided protein engineering to improve the catalytic activity of transaminases under neutral pH conditions by @aoyufe's team?
#biocatalysis #enzyme #machinelearning
🔗doi.org/10.1039/D5QO00423C
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👉Check out recent #research 8,14-seco-ent-Kaurane diterpenoids from Isodon glutinosus: enol–enol tautomerism and antitumor activity by Yang-Yang Fu, Kun Hu, Pema-Tenzin Puno et al. #KIB #CAS
#Glutinosasins
🔗doi.org/10.1039/D5QO00356C
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🔓#OpenAccess #Oligomer
Check out Unveiling stereoselective ladders via photo-oligomerization of a diazaanthracene macrocycle by Jinti Moni Kumar, Bappaditya Gole et al.
🔗doi.org/10.1039/D5QO00159E
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👉Check out recent #research Supramolecular catalysis in the dearomative Michael addition involving nitro-group-activated benzofurans by @a_teamlab
🔗doi.org/10.1039/D5QO00035A
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👉Take a look at Recent developments in organic synthesis for constructing carbon frameworks using transposition strategies by Savita Narayanrao Gat,a Piyusa Priyadarsan Pattanaik and Rambabu Dandela.
#Transpositionreaction
🔗doi.org/10.1039/D5QO00163C
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Inside cover of Issue 09 presents
"Unraveling the α-effect in α-fluorinated carbanionic nucleophiles: origins and synthetic implications" by Jimin Yang and Xiao-Song Xue.
#Free_to_read
🔗 doi.org/10.1039/D5QO00292C
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Issue 09 is available! Please read the cover article
by Hui-Yu Chen, Zhen-Jiang Liu 𝘦𝘵 𝘢𝘭.
#Free_to_read
🔗doi.org/10.1039/D5QO00107B
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👉Another #review from Jihoon Na, Je Uk Kim, Sumin Lee et al: Three-component, stereoselective C–N bond forming alkene difunctionalization. #KU
#Amines #CNbond #difunctionalization
🔗doi.org/10.1039/D5QO00160A
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🔓#OpenAccess #EDA #SET
Read recent #review EDA complex photochemistry as a strategy for C–S bond formation by Helena F. Piedra, Illán Tagarro and Manuel Plaza. @UniOviedo
🔗doi.org/10.1039/D5QO00258C
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🔓#OpenAccess #oxidopyridiniumcycloadditions
Check out this #hot #review article Update for oxidopyridinium cycloadditions and their synthetic applications: advances after Katritzky's pioneering studies by Yoshihiko Yamamoto. @NagoyaUniv_info
🔗doi.org/10.1039/D5QO00115C
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🔥Read recent #hot research article: Pseudo-4-component photoredox-catalyzed alkylative amidination/carbamoylation of styrenes with isocyanides and redox-active esters by Alexandre Simon, Maxime R. Vitale et al. @Sorbonne_Univ_
🔗doi.org/10.1039/D5QO00352K
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👉Read Carbazol-3-olate photosensitizers enable photocatalytic hydrodefluorination and Birch-type reduction reactions by Huilong Kuang, Ryosuke Matsubara et al. @KobeU_Global
#photosensitizers
🔗doi.org/10.1039/D5QO00056D
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🔓#OpenAccess #Alkene #oxofunctionalization
Take a look at this #review Recent developments in alkene oxo-functionalization reactions governed by photoredox methods by @AVallribera, Albert Granados et al.
🔗doi.org/10.1039/D5QO00236B
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👉Read Pd-catalyzed arylative annulation of alkynyl nitriles with boronic acids to functionalized cyclopenten-3-ones/2-indenones by Chada Raji Reddy's team. @csiriict
#arylativecyclization
🔗doi.org/10.1039/D4QO02351J
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👉Read Investigating the stereo-directing effect of remote participating groups on selectivity in the 2-deoxyglycosylation of galactal by Sudhir Kashyap's team. @NIT_Jaipur #Chemicalglycosylation
🔗doi.org/10.1039/D4QO02329C
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🔓#OpenAccess #oxylipids
Check out Synthesis of oxylipids via a boronic ester cycloetherification approach by Markus Tost and Uli Kazmaier. @Saar_Uni
🔗doi.org/10.1039/D5QO00213C
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👉Check out recent #research article Protodefluorinated Selectfluor® heteroaggregate photoinduces direct C(sp3)–H fluorinations without photocatalyst by Shahboz Yakubov and Joshua P. Barham.
@uni_regensburg
🔗doi.org/10.1039/D5QO00149H
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🔓#OpenAccess #CPPHAs
Take a look at recent #research Pd-catalyzed site-specific heteroaromatic C–H/peri-C–H annulative coupling for synthesis of cyclopenta-fused polycyclic heteroarenes by Tienan Jin et al.
@TohokuUniPR
🔗doi.org/10.1039/D5QO00034C
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👉Check out recent research A regioselective and sustainable approach for the synthesis of substituted thieno[2,3-b]chromen-4-ones with pendant imine groups via a base-promoted multicomponent reaction by Abu Taleb Khan et al. @IITGuwahati
🔗doi.org/10.1039/D5QO00228A
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Back cover of Issue 08 showcases research by Weiwu Ren 𝘦𝘵 𝘢𝘭. from @OUC1924
Asymmetric [4 + 3] cycloaddition of hydroxyphenyl indolinones to synthesize novel spirooxindoles
#Free_to_read
🔗 doi.org/10.1039/D5QO00075K
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Issue 08 is available! Please read the cover article:
"Mechanisms of Cu/DMAP-cocatalyzed and DMAP-catalyzed C–N decarboxylative cross-coupling reactions" by Zizhong Liu, Yongsheng Bao 𝘦𝘵 𝘢𝘭.
#Free_to_read
🔗doi.org/10.1039/D4QO02352H
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👉Read Interrupted intramolecular [3 + 2] to 5-endo-dig cyclization: [3 + 2] cycloaddition of nitrile ylides of diazo esters: photo-induced solvent-free gem-diamination to synthesize α-amino-α-substituted α-amino esters by Subhabrata Sen et al.
🔗doi.org/10.1039/D4QO02332C
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🔓#OpenAccess #orthogonaltandemcatalysis #OTC
Recent #research article Orthogonal tandem catalysis involving Au(i)-hydroacyloxylation and Rh(i)-hydroformylation reactions by Nicolas Girard, Gaëlle Blond et al.
🔗doi.org/10.1039/D5QO00084J
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🔥Read A macrocyclic chalcogen bonding catalysis system by Yu-Cheng Gu, Yao Wang when you are free.
This article is also included in themed collection Organic Chemistry Frontiers Emerging Investigator Series 2024–2025.
🔗doi.org/10.1039/D5QO00101C
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Check out the recent article "Asymmetric α-selective allylation of the amide unit of maleimides and alkenyloxindoles by dual-functional Inᴵᴵᴵ/𝘕,𝘕′-dioxide complex" by Shunxi Dong, Xiaoming Feng 𝘦𝘵 𝘢𝘭.
doi.org/10.1039/D4QO02320J
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Check out the recent #open_access article
"Mechanism of formation of chiral allyl SCF₃ compounds 𝘷𝘪𝘢 selenium-catalyzed sulfenofunctionalization of allylboronic acids"
by Kalman J. Szabo, Fahmi Himo 𝘦𝘵 𝘢𝘭.
doi.org/10.1039/D4QO02170C
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🔓#OpenAccess #Mechanophorichydrogels
Read recent #review Mechanophoric hydrogels: when mechanical stress produces useful responses by Franciela Arenhart Soares and Pol Besenius. @uni_mainz_eng
🔗doi.org/10.1039/D4QO02060J
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👉Check out recent research regarding #chemoselective: Chemoselective transition-metal-free acylation of thioamides by N–C(S) bond cleavage using acyclic twisted thioamides by Jin Zhang, Ruihong Wang, Michal Szostak et al.
🔗doi.org/10.1039/D4QO02417F
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