The Greenberg lab investigates processes that affect genome integrity and how they influence human biology
The University of Pennsylvania, Philadelphia, PA
- Tweets 688
- Following 2,236
- Followers 2,774
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Roger Greenberg retweeted
Adam Stevens, PhD, has received a New Innovator Award from the @NIH Director's High-Risk, High-Reward Research program. Stevens uses synthetic biology to study the molecular logic of how cells form and maintain tissues. @Penn_CBIO @stevenschem spr.ly/6019BHrVy5
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Roger Greenberg retweeted
Congratulations to Judy E. Garber, MD, MPH, on receiving the 2026 Basser Global Prize from @BasserBRCA, which recognizes a leading scientist who has advanced BRCA1 and BRCA2-related research. Through her research and clinical leadership, Dr. Garber has helped translate discoveries about BRCA-related cancers into treatments and care guidelines that are now used around the world. Learn more: bit.ly/4yTvyuJ
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Roger Greenberg retweeted
Honored to speak at the MIND-IL Biomed at Tel Aviv University! An impressive coordinated effort across Israel to share discoveries, spotlight trainees, and spark collaborations. Kudos to the organizers @KarenAvraham for bringing the scientific community together! EOB @TLV beach.
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Roger Greenberg retweeted
Congratulations to Zuzana Tothova, MD, PhD, recipient of our Postdoctoral and Graduate Student Association's Mentor-of-the-Year Award. Recognized for her rigorous yet compassionate approach, Dr. Tothova empowers trainees through thoughtful guidance, unwavering support, and a collaborative lab culture that helps young scientists grow with confidence, curiosity, and independence.
ALT Zuzana Tothova, MD, PhD, presented with the Postdoctoral and Graduate Student Association's Mentor-of-the-Year Award from Jose Cancelas, MD, PhD.
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Roger Greenberg retweeted
I am excited to announce that the Marin Lab has just opened! We are based in the @Penn_CBIO at @PennMedicine at the University of Pennsylvania!
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Roger Greenberg retweeted
I’m honored to have been named the next president & CEO of @TheWistar Institute.
I have long admired Wistar’s extraordinary science and collaborative culture and look forward to officially joining the Institute on Nov. 30.
bit.ly/4hvGZnd
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Roger Greenberg retweeted
RESEARCH PAPER: rRNA 5′ETS processing contributes to nucleolar organization and nuclear architecture
By Mendoza-Figueroa et al. and Kathy Fange Liu
➡️ genesdev.cshlp.org/content/4…
@LiuFange @Penn @PennMedicine
#RNA #nucleus #genome
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Roger Greenberg retweeted
Postdoctoral position available! Join us to investigate mechanisms of chromosome instability in human cells.
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Roger Greenberg retweeted
We are saddened by the loss of G&D's long-time Editor, Terri Grodzicker.
When Terri stepped down as Editor in 2022, friends and colleagues wrote about her contributions to the research community. We are re-visiting these pieces, and thinking of her.
➡️ genesdev.cshlp.org/content/3…
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Roger Greenberg retweeted
Congratulations to Vishva for all his groundbreaking discoveries !
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Roger Greenberg retweeted
We’re hiring! 📣 Faculty positions are open at @CBE_Penn @PennEngineers @Penn this year. Apply now and join us! cbe.engineering.upenn.edu/ab…
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Roger Greenberg retweeted
Mechanism of K63-linked polyubiquitin recognition and cleavage by the BRCA1-A complex dlvr.it/TTyPTd (RSS) #nature #MassSpecRSS
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Roger Greenberg retweeted
New research out in @ScienceAdvances finds TRF2 couples muscle stem cell identity to regenerative repair ft. Ji-Hyung Lee, Foteini Mourkioti (@PennOrtho), Ryan Calhoun, Patrick Seale (@PennCDB/ @PennIDOM) & @RogerRogergr (@Penn_CBIO) @IRM_UPenn science.org/doi/10.1126/scia…
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Roger Greenberg retweeted
New research out in @NatureComms finds that the BRCA1-A complex restricts replication fork reversal-dependent DNA repair in ATM deficient cells ft. @arindam_datta1, Yaroslav Morozov, Jinghan Qiu & @RogerRogergr (@Penn_CBIO) @PennGenomeInteg @BasserBRCA nature.com/articles/s41467-0…
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Roger Greenberg retweeted
Meet Ralph Weichselbaum, MD, Chair of Radiation and Cellular Oncology and a leading radiation oncology expert. Follow him for insights on oligometastatic cancer, translational research and advances in cancer care. @rweichselbaum @UChicagoRadonc ow.ly/JBTY50ZjM95
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Roger Greenberg retweeted
A $10M gift will accelerate the development of a new therapy aimed at treating retinal vasculopathy with cerebral leukoencephalopathy (RVCL), a rare genetic and fatal disease with no cure. @rvcl_research @miner_lab spr.ly/6013BEDbU9
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Roger Greenberg retweeted
We're thrilled to announce PCGI Postdoc, Arindam Datta (Greenberg Lab), has published work showing that the BRCA1-A complex blocks replication fork reversal to restrict DNA end resection, defining the molecular basis of chemotherapy response in ATM-mutated cancers:
Congratulations to Arindam Datta @arindam_datta1 on publication of “The BRCA1-A complex restricts replication fork reversal-dependent DNA repair in ATM deficient cells”. nature.com/articles/s41467-0…
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Congratulations to Arindam Datta @arindam_datta1 on publication of “The BRCA1-A complex restricts replication fork reversal-dependent DNA repair in ATM deficient cells”. nature.com/articles/s41467-0…
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BRCA1-A enforces a restrictive chromatin state to suppress fork reversal in ATM deficient cells. This prevents genesis of resection substrates, implicating fork reversal as a key determinant of chemo-response in ATM deficient cells. Great collaboration with @vindigniLab
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Roger Greenberg retweeted
Excited to share our review of molecular regulation/dysregulation of the cGAS/STING pathway. Kudos to co-authors Min-Guk Cho, Rachel Lee, and Jayce Johnson for leading this effort! @UNC_Lineberger @UNC_BCBP
Molecular mechanisms regulating cGAS-STING activation in health and disease: doi.org/10.1172/JCI204548
As part of the JCI’s Review Series on The cGAS-STING pathway: DNA sensing in health and disease, Min-Guk Cho et al. @UNC discuss how disruption or co-option of the processes governing cGAS/STING activation and regulation drive diverse diseases and highlight therapeutic strategies to restore immune balance.
#cGASSTING
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