Physician-Scientist #PancreaticCancer Researcher Assistant Professor, Harvard Medical School @DanaFarber, @DanaFarber_Hale, @BrighamWomens, @HarvardMed
Boston, MA
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NissimLab.org seeks a postdoc for studies on #epigenetics, #PancreaticCancer. Transcription factor networks + epigenetic barriers maintain cell identity. How are these disrupted to promote cancer? Can we target these for interception? DM with interest! @DanaFarber_Hale
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Can we restrain, reverse, or eliminate pancreatic precancers before they become invasive? Following #AACRpan26, @Aiims1742 @BenStanger01 @MadameSurgeon and I discuss hopes for #PancreaticCancer interception in @Nature.
nature.com/articles/d41586-0…
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Fantastic science at #AACRpan26! Grateful for the enthusiasm and feedback on our work developing a PDAC interception strategy by targeting NR5A2. Thanks to our team as we work toward new options for high-risk individuals! @DanaFarber_Hale @AACR #PancreaticCancer
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From Detection to Interception: Redefining the Earliest Stages of Pancreatic Cancer—#AACRpan26 cochair Diane M. Simeone, Ben Z. Stanger, Nuria Mallats, Raymond Wadlow, and @SaharNissim addressed this topic in a plenary at the AACR Conference on Pancreatic Cancer.
@MadameSurgeon
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TY @Aiims1742!
Thrilled to share our new @AGA_CMGH paper!
Using FixNCut scRNA-seq, we uncover novel acinar metaplastic cell states and precancer programs in pancreas disease.
sciencedirect.com/science/ar…
Led by the amazing @Aney_Katie and Woo-Jeong 👏🧵👇
New paper in @AGA_CMGH from @SaharNissim
Novel Acinar Metaplastic States Uncovered in Exocrine Pancreas Disease
sciencedirect.com/science/ar…
Using FixNCut (which preserves RNA integrity in the pancreas), this study explores acinar plasticity & lineage state heterogeneity in PanINs.
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(13/14) Many thanks to the support of @DanaFarber_Hale, @BWHGenetics, @BrighamGI, @TheVFoundation, and our generous and visionary philanthropic donors. 🙏
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(14/14) Interested in acinar metaplasia or pancreas precancer biology?
Give FixNCut a try—and please reach out with questions or ideas. We're excited to keep pushing this field forward and ultimately inform new early detection and interception strategies for #PancreaticCancer !
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So proud of @AneyKatie drawing a crowd at @AACR PDAC! Beautiful story in the works to understand how acinar identity unravels on the way to cancer.
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Thrilled to announce our @AGA_Gastro paper, where we tackle the challenging exocrine #pancreas context to achieve unprecedented scRNA-seq definition of cell landscapes in homeostasis, #AcutePancreatitis, and recovery. Led by NissimLab @aneykatie + Woo-Jeong Jeong. 🧵👇
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Give FixNCut a try and please reach out with any comments or questions… we’re excited to compare data and illuminate the field together!
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