Bioinformatics & Biostatistics / @sanchezgaya.bsky.social /Developing POSTRE github.com/vicsanga/Postre to improve human genetic diagnostics
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Víctor Sánchez Gaya retweeted
#EMBLChromatin keeps being awesome: fantastic talks, lots of networking and troubleshooting! But guess who is also multitasking? ZIC2! Particularly during neural induction! Come by this afternoon to check poster 158 and I’ll tell you all about it 😉 @EMBLEvents #RadaIglesiasLab
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It was great to participate at the #ComputationalBiology & #Bioinformatics CSIC connection event last week in Madrid. I could talk about POSTRE, our solution for interpreting the effects of structural variants github.com/vicsanga/Postre, and discover great people & projects.
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Pequeño resumen de nuestro último trabajo en el @radaiglesiasLab (nature.com/articles/s41467-0…) realizado por @unican.
INVESTIGACIÓN 🔬 | Investigadores del @IBBTEC descubren un nuevo mecanismo que influye en la correcta expresión génica durante el desarrollo embrionario
Podrá ayudar a diagnosticar patologías causadas por variantes estructurales que alteran la organización 3D del genoma
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Víctor Sánchez Gaya retweeted
📢3-year postdoctoral fellow position available
Interested in gene regulation and deciphering the molecular mechanisms of human disease, join us at the @MRC_LMS in the beautiful city of London
For more details, please visit lms.mrc.ac.uk/vacancies/mrc-…
✉️l.allou@lms.mrc.ac.uk
🙏RT
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All set at #ECCB2024 after today's opening event! If you want to talk about DNA Structural Variants interpretation and their impact on gene-enhancer regulation... visit P407 poster tomorrow! github.com/vicsanga/Postre @radaIglesiasLab @ECCBinfo
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Víctor Sánchez Gaya retweeted
Thrilled to share that our work from the Noh Lab @embl is now published in its peer-reviewed form @NatureComms! 🥳🥳🥳
Curious how histone H3.3 K9 and K27 residues contribute to transcriptional regulation?
Here's a sneak peek...🧵 (1/n)
📄rdcu.be/dSyQz
#chromatin
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Glad to see the revised version of our latest preprint out today in @NatureComms 🥳🥳. Here we have studied how developmental genes can contribute to the insulation of their own regulatory domains nature.com/articles/s41467-0…
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Main points, quoting @RadaIglesiasLab:
(1) CTCF cannot do it all by itself
(2) CTCF prevents undesirable enhancer-gene contacts (i.e. physical insulation)
(3) Developmental genes contribute to regulatory insulation through non-structural mechanisms involving promoter competition
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Special thanks to @thais_ealo for her titanic work, to Alvaro for his top guidance & supervision, and the rest of the @RadaIglesiasLab team for their help, support and feedback.
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Víctor Sánchez Gaya retweeted
[CHARLA]🔵"El genoma en 3D: La estructura de nuestro ADN importa"
🧬 Álvaro Rada (@IBBTEC)
📍@AteneoSantander
🔬Miércoles 08/05/2024, 19:30
ℹ️ifca.unican.es/es-es/seminar…
🧫Entrada libre hasta completar aforo
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Víctor Sánchez Gaya retweeted
⚠️New #Prelight! Covering an elegant study by @guillaumeandrey lab on how enhancer usage changes over time using the developing limb as a model.Luckily for @IBBTEC members, 1st author @Raquel_Rouco is tomorrow´s speaker at our External Seminar! @preLights prelights.biologists.com/?po…
ALT Dual-fluorophore tracking of Shox2 locus activity.
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Víctor Sánchez Gaya retweeted
EL primero congreso de #congresosebibc2024 ya está aquí! Será del 16 al 18 de octubre de 2024 en Feria Valencia. La recepción de abstracts ya está abierta, apunta la fecha e inscríbete! Seguiremos actualizando próximamente.
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Víctor Sánchez Gaya retweeted
We advocate for equity in healthcare and access to treatments for those living with rare diseases. Genetic research plays a vital role in advancing treatments and diagnostics. Let's make a difference in the lives of millions.🌍#RareDiseaseDay #ASHG rarediseaseday.org/
ALT Rare Disease Day 2024
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🥳 Excited to see a Case Report where POSTRE github.com/vicsanga/Postre, our SV interpretation tool from @RadaIglesiasLab, helped in the detection of a pathogenic loss of FOXC1 expression through an enhancer disconnection event caused by an inversion mdpi.com/1422-0067/25/5/2669 👁️👇
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Víctor Sánchez Gaya retweeted
Hoy en el IES Torres Quevedo tuve el placer de compartir mi pasión por la ciencia dando una charla divulgativa y participando en un podcast dedicado al #11F #díamujeryniñaenciencia. Es crucial motivar a las futuras generaciones a seguir sus sueños sin límites. ¡Somos imparables!
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Víctor Sánchez Gaya retweeted
Last two days to apply and join the lab as postdoc fellow! #singlecell #3Dgenome #enhancer #plasticity #glioblastoma #cancerneuroscience
📢 2-year postdoc position!!
Join us @Remeseiro_Lab to study #3DGenomics & #CellularPlasticity in #Glioblastoma #CancerNeuroscience. If you have background in #singlecell #omics and/or #bioinformatics, you're a good match to our team. Apply now 👇👇
Please RT RT RT 🤗
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Ending one of the best weekends ever. Thx @malte_spielmann , @SVergult and @MarianRosL for joining my PhD evaluation committee, it was a true privilege. Thx Alvaro for your guidance and thx to all @RadaIglesiasLab members, family & friends for their support. Love you all ♥️
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Happy to see our new preprint out 🥳🥳. In this project we have analyzed how developmental genes can contribute to strengthen the insulation of their own regulatory domains. We hope you enjoy the reading! @RadaIglesiasLab @generegulation @thais_ealo
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Víctor Sánchez Gaya retweeted
Do you know the heads of Conesa Lab? @anaconesa at @i2sysbio and Sonia Tarazona at @UPV
If want to know more about their research career and current projects visit our website conesalab.org/group/
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