Professor, PI, Cell and Molecular Biologist. Study genome integrity and cancer etiology. Fun of Xenopus laevis. Opinions are my own.

Charlotte, NC
We are excited to invite you to the inaugural 2026 Southeastern Symposium on Genome Integrity and Chromatin Regulation, to be held at UNC Charlotte on June 15, 2026. Details: biology.charlotte.edu/ssgicr… @unccharlotte @ASBMB @EMGSUS @FASEBorg @ncbiotech
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Trilled and humbled to received the 2025 Outstanding Faculty Research Award by Department of Biological Sciences at UNC Charlotte. Thankful to my mentors, collaborators, current/former lab members, friends and family. ⁦⁦@EMGSUS⁩ @ASBMB⁩ ⁦⁦⁦@unccharlotte⁩
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Thrilled to spotlight the Charlotte Biology and Biotechnology Exchange Group at the NCBiotech Summit 2025 @unccharlotte @ncbiotech
Shan Yan, Ph.D. @unccharlotte shares how the Charlotte Biology and Biotech exchange group has hosted 36 distinguished speaker since 2017. CBB plans to expand the community and collaborations for continued impact. #NCBiotechSummit2025
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First day of 2025 EMGS annual meeting ⁦@EMGSUS⁩
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Congratulations to Dr. Anne McMahon, newly minted PhD from the Yan lab.
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Ready for the session of Histone modifications mechanisms and therapeutic targeting @ASBMB annual meeting
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Please join me to congratulate my colleague Dr. Andrew Truman @TrumanLab as the recipient of the 2024 Outstanding Biological Sciences Faculty Research Award! Well deserved Andy! Check out more details: biology.charlotte.edu/dr-and… @unccharlotte @49erAlumni @UNCCFaculty
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Call for nominations of five EMGS awards: 1) EMGS award: 2)Alexander Hollaender Award: 3)EMGS Service Award: 4) EMGS Education Award: 5) EMGS Young Scientist Award: T Deadline: December 31, 2024. Check more details: lnkd.in/ertVVWjG
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Pleased to share our perspective on APE1 in DNA damage response as part of the Special Issue in DNA Repair. Congratulations to @HaichaoZhao9 and co-authors Christine Richardson, Ian Marriott, In Hong Yang! @unccharlotte @UNCCBiology weblink: sciencedirect.com/science/ar…
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Deb Thomas, Associate Vice Chancellor of UNC Charlotte, kicked off the 2024 Charlotte Biomedical Sciences Symposium. Doug Edgeton CEO of North Carolina Biotechnology Center updated us the biomedical landscape in NC. More to go for the day…
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Glad to share a lab research article @NatureComms Great work by co-authors Haichao Zhao @HaichaoZhao9 Jia Li @Jiali17022980 Zhongsheng You @YouLab_WashU Howard Lindsay @Howard_Lindsay @unccharlotte @FASEBorg @EMGSUS @ASBMB Check it out: nature.com/articles/s41467-0…
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Guess who is visiting and ready for a seminar?
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UNC Charlotte vs Uptown Charlotte
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Thanks to ⁦@LeungLab⁩ for a great Charlotte Biology and Biotechnology distinguished seminar on biomolecular condensates, virus infection, PARPs and PAR code. ⁦@unccharlotte⁩ ⁦@EMGSUS⁩ ⁦@ASBMB⁩ ⁦@FASEBorg⁩ ⁦@ncbiotech⁩
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Had a good evening yesterday attending the 2024 Million Dollar Research Circle @unccharlotte and reception with @SongLab_UNCC @TrumanLab @adam_reitzel @dan_gard @KristenEFunk @HawleLab and Ian Marriott @UNCCBiology along with other honorees @ChancellorGaber
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Congratulations to ⁦@ShanYanLab⁩ Research Associate ⁦@HaichaoZhao9⁩ winning ⁦@ASBMB⁩ travel award. Please stop by Poster board #42 today to checkout APE1 in DDR, LLPS condensates etc ⁦@EMGSUS⁩ ⁦@FASEBorg⁩ ⁦@unccharlotte⁩
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⁦@jbiolchem⁩ symposium ⁦@ASBMB⁩ meeting kicked off by ⁦⁦@ChiefEditorJBC⁩ , and composed by three outstanding talks by editors and scientists ⁦@HenrikDohlman⁩ ⁦@DrBrianStrahl⁩ ⁦⁦@KLabGPCR⁩.
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Have a nice dinner with BER friends working on DNA glycosylase, polymerase, APE1/2, and DNA ligase etc. The whole BER pathway is covered and the session room was packed at @ASBMB @Freudlab @sheiladavidUCD
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Day 1 of the ⁦@ASBMB⁩ annual meeting at San Antonio. Season 1 on BER pathway!
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Merry Christmas and Happy Holidays!
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Glad to be highlighted as game-changing research in Best of 2023 - Niner Nation's Top Headlines @unccharlotte @UNCCBiology @UNCCFaculty @EMGSUS @FASEBorg @ASBMB view.mc.charlotte.edu/?qs=bf…
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When meeting with a DNA double strand break, what repair pathway to choose?
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Congratulations to the inaugural Outstanding Faculty Research Awardee in Biological Sciences Danillo Augusto @dan_gard & Bao-Hua Song @SongLab_UNCC! Well deserved! @unccharlotte @UNCCFaculty @UNCCBiology @CLT_ABSGS
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Anne presented her perspective on APE2 in cancer context published ⁦@NAR_Cancer_EIC⁩ and demonstrated the first PTM regulation of APE2 protein in #proteiostasis at the Symposium ⁦@EMGSUS⁩ ⁦@FASEBorg⁩ ⁦@ASBMB⁩ ⁦@UNCCBiology⁩
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Haichao from the lab started the oral presentation session and highlighted several regulatory mechanisms of APE1 in the DDR pathways in ⁦@NAR_Open⁩ ⁦@eLife⁩ ⁦⁦@TrendsCellBio⁩ etc. ⁦@EMGSUS⁩ ⁦@FASEBorg⁩ ⁦⁦@ASBMB⁩ ⁦⁦@UNCCBiology⁩
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Dr. Meghan Stark kicked off the 2023 Research Symposium ⁦@UNCCBiology⁩ and offered advice on alternative career paths such as #sciencepolicy etc. ⁦@EMGSUS⁩ ⁦@FASEBorg⁩ ⁦@ASBMB⁩
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Does this art look like a DNA strand?
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Dr. Huadong Pei from ⁦@LombardiCancer⁩ delivered a Charlotte Biology and Biotechnology distinguished seminar on histidine phosphorylation in genome integrity and cancer today! ⁦@unccharlotte⁩ ⁦@ncbiotech⁩ ⁦@EMGSUS⁩ ⁦@FASEBorg⁩
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I am very honored and humbled to accept the 2023 EMGS Education Award @EMGSUS . Greatly appreciate the support and help from my mentors, mentees, collaborators, colleagues, friends, and family over the years. Thank y'all! This EMGS award means a lot to me.
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Glad to Co-Chair w/ ⁦@structureSara⁩ for Challenges in DNA replication session ⁦@EMGSUS⁩ mtg. Great speakers ⁦@Hedglin_Lab⁩ ⁦@JenMasonPhD⁩ ⁦@FouquerelElise⁩ ⁦@kara_bernstein⁩ ⁦⁦@jaigeeth⁩ & Justin Ling & wonderful science!
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Congratulations to Graduate student Anne McMahon and Research Associate ⁦@Jiali17022980⁩ for a good job presenting their research on APE1/2 ⁦@EMGSUS⁩ meeting and Travel Awards from EMGS. ⁦@unccharlotte⁩ ⁦@UNCCBiology⁩
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Stage for the DNA Repair & Mutagenic Mechanism SIG meeting is setup at the annual EMGS meeting @EMGSUS co-Chaired by @DNAmyWhitaker @FouquerelElise @SciRy2
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Research highlight: Glad to share a @PNASNews Commentary paper by PhD student Garrett Driscoll @UNCCBiology @ShanYanLab titled "Maintaining chromosome and genome stability by the RPA–RNF20–SNF2H cascade". @unccharlotte @EMGSUS @FASEBorg PNAS pnas.org/doi/10.1073/pnas.23…
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Grant/award highlight: Congratulations to my colleague Dr. Danillo Augusto @UNCCBiology on the new 5-year NIH/NIAID R01 award totaling $3,312,445.00 to study "The Variation of the NK Cell Receptome in Pemphigus". Well deserved! @unccharlotte @ChancellorGaber
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Research Highlight: Congratulations to my colleague @KristenEFunk and her graduate student Britanie Blackhurst @UNCCBiology on their News & Views @NatRevNeurol "Viral pathogens increase risk of neurodegenerative disease"
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Mechanism underlying the recruitment of ATR/ATRIP to ssDNA gaps is an outstanding question for ~20 years. Excited to share our paper @eLife:APE1 recruits ATRIP to ssDNA in an RPA-dependent and -independent manner to promote the ATR DNA damage response doi.org/10.7554/eLife.82324
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Glad to have an opportunity to have a video conference talk to the NIH DNA Repair Interest Group on June 13, 2023 at 12:30pm. "Functional studies of APE1/2 in genome integrity and cancer etiology" @EMGSUS @FASEBorg @UNCCBiology oir.nih.gov/sigs/dna-repair-…
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Glad to have Dr. Tanya Paull for the CBB Distinguished Seminar on ATM functions in DNA damage and protein dysfunction in the brain. #DNAdamage #DNArepair #ATM
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Spring is coming to Charlotte!
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Inspirisional seminar by Dr. Richard Morimoto on proteostasis hsp70 hsp90 and conformational network idea from @NorthwesternU @UNCCBiology
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After getting another deadline met today, enjoyed a concert performed by PHS wind ensemble!
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@FASEBorg CHD, NC delegates @ShanYanLab @unccharlotte & @SamratD40417560 @duke visited the Offices of @SenThomTillis @ValFoushee @RepAdams @RepDeborahRoss for increased & sustainable funding for @nih & @nsf. #FASEBOnTheHill @EMGSUS @ChancellorGaber
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I voted early!
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Had a great time with Dr. Huadong Pei at Georgetown Lombardi Cancer Center @Georgetown . Good discussion on cancer research and DNA repair and beyond...
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Glad to participate in the ⁦@FASEBorg⁩ Science Policy Symposium in person. FASEB president Kevin Kregel welcomed all. Good discussions on how to promote biological and biomedical research, education workforce ⁦@EMGSUS⁩ ⁦@unccharlotte⁩ ⁦
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Great collaborative editorial team @rwsobol @BrownUniversity @zhao_jianjun @CCLRI @mgkemp77 @wrightstate @ShanYanLab @unccharlotte working with authors and reviewers to put together 7 research articles and 2 review paper in cancer biology & environment health. Check it out &RT
Thanks to a great Co-Editorial Team @ShanYanLab @mgkemp77 @zhao_jianjun to help bring this issue together. frontiersin.org/articles/10.…
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DNA repair blues #ICEM2022 ⁦@EMGSUS⁩
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“Don’t be blown down by big wind!”From Mo Yan, The Nobel Prize in Literature 2012
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Our fourth CBB speaker in AY21-22 is Dr. Karlene Cimprich @KarleneCimprich from Stanford University. Her seminar titled "RNA Meets DNA: Dangerous Liaisons in the Genome" will be at 12:30pm-1:30pm EDT, May 6, 2022 (today) zoom: uncc.zoom.us/j/92732591534 (Meeting ID: 927 3259 1534)
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Last classroom meeting for Biol 6102/8102 Cell & Molecular Biology with a great group of graduate students and young professionals! An integration of lectures, paper discussions, and career discussions. Can anyone point out who are in the nice class picture?
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