Most neurons in the cortex remain silent, even during sensory stimulation and behavior. What are these silent neurons good for? This is known as the “dark matter problem” of the brain. We address this problem in our @NeuroCellPress study led by @omgaulddoi.org/10.1016/j.neuron.202…
Thrilled to share my PhD work, out in @nature today. @fisekmehmet & I developed an all-optical approach to study long-range connectivity across brain areas. Upshot: visual feedback is spatially organized & nonlinearly integrated in V1 apical dendrites. nature.com/articles/s41586-0…
Want to identify active synapses or estimate synaptic weights in your high-resolution connectome? Our latest preprint combines 2-photon targeted functional labelling in vivo with machine learning readout of focused ion beam scanning EM (FIBSEM) data. biorxiv.org/content/10.1101/…
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