Many minor surgeries are done with propofol sedation and nerve block, these patients do not need deep general anesthesia and get enough propofol so they sleep and breathe without support. And they dream, especially with propofol. The point is the nerve block covers their pain and they’re not intended to be fully asleep. There are rare cases of patients being awake when they are supposed to be anesthetized. That’s bad.

No. Microtubule quantum processes are the connection to Platonic spacetime geometry.

DDG isn’t fringe. It’s just not yet developed. We will present ‘Introducing the DDG…’ as a poster at the Society for Neuroscience meeting in Washington DC Thursday afternoon November 17. abstractsonline.com/pp8/#!/2… But which triplets are you talking about?

I don’t feel downtrodden, they’re just stinking up the field by dumbing down neuroscience. But time is on my side. Warm temperature brain jelly quantum computers and Dodeconography are just around the corner.

Congrats to Dr Emory Brown! He’s been a leader in anesthesiology research the past few decades. Like him I devoted my career to anesthetic action which selectively blocks consciousness, sparing non-conscious brain activities. At the turn of the 20th century Meyer and Overton showed all anesthetics act inside one target molecule, later shown to be a protein. Because anesthesia acts selectively (despite binding nonspecifically) the selective target of anesthesia is likely the key to consciousness. Like most anesthesia researchers Emory Brown has favored a group of neuronal membrane receptor channels for GABA_A and NMDA receptors mediating anesthesia and presumably consciousness. But in 2008 that possibility was ruled out pubmed.ncbi.nlm.nih.gov/1871… Meanwhile more and more evidence has accrued that anesthesia acts on microtubules inside neurons and glia by quantum interactions. Proteomics, genomic, optogenetic and pharmacological dynamic studies from the Eckenhoff group at Penn have shown anesthesia acts in microtubules, See also academic.oup.com/nc/article/… nature.com/articles/s41598-0… pubmed.ncbi.nlm.nih.gov/3696… In his article Dr Brown doesn’t mention a mechanism for anesthesia. The conventional wisdom of membrane receptors is defeated ( e.g. active GABA_A receptors in unconscious propofol anesthetized animals in Earl Miller ‘oddball studies’). It’s microtubules or nothing. Conveniently there’s a theory of consciousness attached to microtubules. pubmed.ncbi.nlm.nih.gov/3578…

The brains of anesthetized unconscious patients are quite active, including sensory evoked potentials. Their membranes are signaling but no consciousness.

Anil if you actually considered biological naturalism as in the Orch OR theory you’d probably conclude biominetic quantum AI CAN be conscious. iopscience.iop.org/article/1… Why do you exclude Orch OR, the theory of consciousness with more explanatory power, biological connection and experimental evidence than all the other theories combined? Serious question. If another theory has more evidence, what is it? The selective action of anesthesia is the only way to answer this. academic.oup.com/nc/article/…

Orch OR comes closest to the hard problem by identifying conscious moments with OR (quantum gravity-) mediated collapse of the wavefunction at t =h/E. According to Nobel laureate Sir Roger Penrose this is the only source for noncomputable causal action available in the universe, and thus the only source for consciousness. Many others including Chalmers say it is funda-mental but lack a physics-based plausible mechanism connecting consciousness to the universe. Roger and Orch OR have it, plus very strong evidence that anesthesia selectively blocks consciousness via quantum interactions with microtubules. The cartoon neuron theories plus IIT have no explanatory power, neurological connection nor experimental evidence. Orch OR has them all. I’ve been challenging the neuro-influencers who never discuss or acknowledge Orch OR for a couple years and they don’t respond. Anil talks about biological naturalism but omits Orch OR and microtubules (can’t be mitochondria, anesthesia doesn’t make our patients acidotic.). But it’s not a conspiracy.

So it’s a conspiracy to keep Orch OR out of the public eye? That is suspicious

Roger hoodwinked them. He said radiation would not be detected and it wasn’t. He did not say radiation wasn’t generated with OR. He later explained (in his chapter in Shan Gao’s book ‘Consciousness and Quantum Mechanics’) that radiation energy was produced by OR but erased by backward time effects. The Gran Sass-holes threw their own favorite Diosi OR as well as Penrose OR and Orch OR under the bus for no reason. Serves them right. They invited me to give a talk to their group and Diosi was very apologetic. Their strategic leader Catalina Curceanu wasn’t.

Then explain the double slit experiment. Explain why anesthesia selectively blocks consciousness by quantum forces. Explain spatiotemporal binding in the brain without quantum interactions. Explain consciousness with strictly classical mechanisms. We’ll be waiting.

Wrong!! The ‘Gran Sasso’ experiment was a botched hit job and totally dishonest. They tested the Diosi version of quantum gravity OR collapse versus the Penrose version, both predicting OR at time t =h/E_G. But Diosi predicted energy would be generated and Penrose said no energy would be detected. They (including Diosi) did the experiment under Gran Sasso mountain and NO energy was detected, validating Penrose OR. But they then claimed the assumptions must be wrong and changed the superposition separation distance 4 orders of magnitude larger, smearing the separation distance. Ironically the smear repeated Tegmark’s apparent ‘mistake’ of 7 orders of magnitude smearing which was disproved, but still wrongly cited as refuting Orch OR. By smearing the superposition separation distance the Gran Sass-holes seemingly invalidated both Diosi and Penrose versions, so they then applied it (for no apparent reason other than to refute SOMETHING and claimed to refute Orch OR. Total bullshit. They should be ashamed. Gran Sass-holes! sciencedirect.com/science/ar…

Orch OR occurs when t=h/E_G where E_G is the gravitational self energy of superposition, h is Planck-Dirac constant and t the time it occurs. Quantum gravity is the mechanism. Sorry it’s mysterious. Have you read ‘The emperor’s new mind’ by Nobel laureate Sir Roger Penrose? It’s his idea and a damn clever way to link our consciousness to the fine scale dynamics and geometry of the universe. Thats quantum gravity. What’s wrong with solving two mysteries ( measurement and consciousness) with one solution, objective reduction? Wouldn’t Occam’s razor dictate that?

Free will doesn’t mean you know the actual outcome, just the intended outcome. And read ‘Emperor’s new mind’ before trivializing noncomputability. But you’re not covering the basic problem that in cartoon neuronism, consciousness comes too late. Quantum brain biology to the rescue. pmc.ncbi.nlm.nih.gov/article…

You can change the subject but can’t change the fact AI is clueless about consciousness because it follows cartoon neurocomputation and suppresses Orch OR, the only theory with evidence. Do you disagree?

Anil how can you talk about evidence when you pointedly ignore and suppress the Orch OR theory of consciousness which is the only theory with supportive evidence. It’s based on selective action of anesthesia on consciousness via quantum effects in microtubules. Why the coverup? What’s the payoff?

Dear Henry Shevlin I AM a biological naturalist. All conscious organisms utilize quantum effects in microtubules to organize conscious activities. I know that because anesthesia acts by quantum effects in microtubules on all organisms. academic.oup.com/nc/article/… pubmed.ncbi.nlm.nih.gov/3696… nature.com/articles/s41598-0… Orch OR is a BN theory of consciousness with BY FAR the most experimental support, biological connection and explanatory power among all theories of consciousness. pubmed.ncbi.nlm.nih.gov/3578… It is based on quantum processes in microtubules which have been shown to be inhibited by anesthesia. And yet Orch OR has been suppressed, ignored and was banned from ASSC by David Chalmers. Anil Seth talks incessantly about biological naturalism without mentioning Orch OR. Ned Block writes about BN without looking inside neurons or considering Orch OR. The fix is in. AI-backed interests are funding Neurocomputational labs to promote ‘cartoon neuron’ models incompatible with biology and consciousness. The NYU school run by Chalmers and Block won’t mention Orch OR in their curriculum. Ironically the future of AI is in warm temperature organic gel quantum computers. LLMs and their huge energy costs will be obsolete. iopscience.iop.org/article/1… Where do you stand Henry Shevlin? Are you intellectually a lemming or a scientist? Seems like you’re reaching out to BN. Is it to have a reason to reject them or are you genuinely interested in how the brain works ? (unlike Chalmers, Seth, Block and Christof Koch who also pointedly ignores Orch OR.) It’s a coverup. Microtubules are polyatomic time crystals which can act as qubits at room temperature. DeepMind should be all over them but instead see them as a threat apparently. ingentaconnect.com/content/i…

Anesthetics bind nonspecifically by weak quantum forces but act selectively, blocking consciousness while sparing nonconscious brain activities. That’s because anesthetics randomize their quantum binding targets, but only quantum activities in conscious dynamics in microtubules are ordered, and not already randomized.

With Joseph Jacks and Anirban Bandyopadhyay at Women’s NBA Championship Finals in San Francisco. The Atlanta Dream beat our Golden State Valkyries to even the series at 1-1.

Anil, would AI based on Orch OR theory be conscious? You’ve only ruled out cartoon neuron approaches. The type of biomimetic organic ‘brain jelly’ quantum device in this paper is likely be sensitive to anesthesia, and could utilize Orch OR and be conscious. Plus it requires very little energy and no cooling. iopscience.iop.org/article/1…