The Gregory lab @DukeU studies disease mechanism using scRNAseq & spatial molecular technologies. Focus on brain tumors, Alzheimer's and MS 🧠 Home to #DukeMGC
Durham, North Carolina
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At #ASHG26, Gregory lab PhD student, Emma Hatchell, presented her poster 'In Situ Sequencing Reveals Distinct Host-Herpesvirus Microenvironments in #MS Spinal Cord Lesions', leading to some great discussions. We love sharing our work 🧬🧠
#Xenium #MultipleSclerosis #Herpesvirus
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Thank you to @GeneticsSociety for having Gregory lab PhD student, Emma Hatchell, and our fearless leader @sgrayg as panel moderators for #ASHG26! 🧬
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Thank you to everyone who came out to the #DukeSCI Colloquium! It was a great day filled with awesome science, good conversation, and opportunities for new collaborations. We already can't wait for next year🤩🧬
A special thank you to our keynote speakers @RongFan8 & @junyue_cao
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Congratulations to Gregory lab PhD student Max Bucklan on passing his prelim exam this week!
We are so proud of you Max 🍾🥂🥳
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Meet Sicheng Jing, a Master's student from @DukeBiostats. Following her B.S. in #Bioinformatics from @UCSanDiego, she is studying computational #genomics, transcript isoforms & protein structure in #neurological diseases. 🧬
Sicheng enjoys trying new recipes, and watching anime.
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This week, the #DukeMGC ran our 2500th #SingleCell sample 🎊🎉
More than 10 species and 100s of projects later and we still love generating high quality #scRNAseq data for our customers!
For more info on our single cell services, visit: dmpi.duke.edu/cores/molecula…
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Gregory lab PhD student, Max Bucklan, has been selected as a winner of the @LaskerFDN Video Contest!!
He used #Lego to explain his work on atypical teratoid rhabdoid tumors (#ATRT), a rare #pediatric #BrainTumor. Congratulations Max!
Check it out:
laskerfoundation.org/meet-th…
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Last week, our fearless leader @sgrayg and the rest of the @GeneticsSociety Program Committee went to Capitol Hill to advocate for human #genetics and #genomics research, highlighting the importance of NIH funding 🧬
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This summer, we are hosting Samuelle, a senior of @UNRCabnr & @UNRLiberalArts for the @MSSociety Undergrad Summer Research Program! She is examining cortical samples from #MS patients & their #genomic data. Outside the lab, she hangs out with her rabbit, Cowie (looks like a cow).
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The #DukeSCIRIP colloquium is back for another year to highlight #SingleCell and #spatial science happening at Duke, @UNC, @NCState & @NCCU!
This will be a day-long event (8:15am-5pm), with both academic & corporate talks.
For more info and to register: dmpi.duke.edu/duke-single-ce…
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#DukeMGC & @illumina held a seminar to present Illumina #SingleCell projects here at Duke and results from the MGC's recent benchmarking paper (biorxiv.org/content/10.64898…)
JULY 1: Illumina single cell will be available at the MGC! Reach out for a consult: DMPI-MGC@dm.duke.edu
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Meet Zach, a rising Duke sophomore and our new undergrad in the lab!
He will be working with #Xenium #SpatialOmics data to examine #CNStissue #lesions in #Cancer patients with hypermutated #BrainTumors. Outside of the lab, he enjoys playing sports and hiking 🧠🌄
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To celebrate Khooshbu's time the #DukeMGC, we went to Top Golf!
We had an un-fore-gettable time 🤩⛳️🏌️♀️
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The final #DukeSCIRIP seminar for this academic year will be 6/3 from 12-1pm, featuring a talk from Dr. Jian Hu of @EmoryUniversity
'Uncovering the Dark Spatial Transcriptomes in Brain'
For more information or to join virtually, please visit our website: dmpi.duke.edu/duke-single-ce…
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Meet Sicheng, our new Master’s student from @DukeBiostats !
She will be working on developing an analysis pipeline for #SingleCell #LongRead isoform data, with a focus on ORF annotation, NMD prediction, & protein structure prediction in the context of neurological diseases 🧬🧠
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Last weekend, we had the opportunity to take part in @prtbtcatduke #AngelsAmongUs 5K & Walk for Hope!
Gregory lab student, Lauren Whaley, shared her work on #GBM in the #BrainTumor science tent and Team BTOP was able to help in the fundraising of $2.8mi for brain tumor research
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Congrats to #DukeMGC's Khooshbu Patel, who is starting her PhD in Pharmaceutical Outcomes & Policy @UNC Fall '26. She will focus on translating healthcare innovations, #Genomics & #PrecisionMedicine into clinical practice.
Khooshbu, we are so proud and wish you all the best!
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Another year of #GliaCamp under our belts!
Shoutout to Gregory lab PhD students for sharing their #Xenium data: Emma with a talk on #MS & Lauren with a poster on #GBM 🧠🧬
Thanks to @FilianoLab for spearheading organization of this event. We look forward to it every year 🤩
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Next installment of #DukeSCIRIP is NEXT WEEK on Wednesday 12-1pm!
Featuring talks from the Snyder lab & Kay lab on #SpatialTranscriptomics applications in #cancer
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A big congratulations to Gregory Lab PhD student, Odmaa Bayaraa, on receiving the @dukesom Dean's Award for Research Excellence!
We are all so proud of her hard work and dedication and cannot wait to see what she does next 🥳🧠
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The results are in - the Gregory Lab's 3rd annual #LabAppreciationWeek podium is as follows:
1st: Ellora Haukenfrers
2nd: Julia Smith
3rd: Emma Hatchell
But the real winner is Emily Hocke for organizing this whole week for us! We already can't wait for next year... 🌟🧑🔬👏
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To wrap up our #LabAppreciationWeek, we had a lab potluck and played Jeopardy, created by #DukeMGC's Emily Hocke & Alan Smith 🤩🍲
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Fourth event of our annual lab olympics was Lab Tape Shuffleboard! 🎯🧑🔬
It was a close game, but #DukeMGC Research Tech, Alan Smith pulled away in the second round to secure a win 🏆
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Third event of our lab olympics was the dry ice spoon race 🧊🥄
Disaster struck in the final heat, where our fearless leader dropped & crushed his dry ice piece.. but Odmaa Bayaraa persisted and pulled off a win! 🏃
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Second event of our annual lab olympics was the glove swap race!
We put gloves on, do 10 jumping jacks, and then race to take the gloves off and put them back on ⏲️🧤
Winner was honorary Gregory lab member, Dianne Cruz 🏆
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First up for the 3rd annual Gregory Lab lab olympics was the 'pipette tip ejection' competition!
Our fearless leader @sgrayg sunk a 25-point shot to seal the win 🏆
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Socks & sandals, lots of color, and some fun accessories to boot... day 3 of #LabAppreciationWeek is WACKY WEDNESDAY 🥳
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What do three black cats and a bunny all have in common...?
They love #LabAppreciationWeek!
Day 2: 'Dress as Your Pet or Favorite Animal Day'
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We cannot wait to see what @10xGenomics #Atera brings...
Some highlights:
- WT profiling @ 18,000+ plex w/ options for customization
- higher throughput
- single-cell level sensitivity
- lower cost-per-sample
Let's see what's possible with the impossible!! 🧬🔬💻🤩
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Had a great time presenting Lauren Whaley's work at the #AACR26 poster sesson!
'Integrative #SingleNuclei #SpatialTranscriptomic profiling of primary and recurrent human #glioblastoma reveals cell-specific EGFRvIII expression & ANXA1 signaling axis'
#GBM 🧬🧠
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#AACR26 is underway and our fearless leader happened to run into Gregory lab alum, Santosh Gupta! We love getting a chance to reconnect with old lab mates.
Talk about cell-ebrating #LabAppreciationWeek! All the way from San Diego to Durham 🛫🥳
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It's the Gregory lab's 3rd annual #LabAppreciationWeek!! We can't wait to share what we get up to this week in celebration of our lab's hard work, all year round🧬😁
First on the docket is Decades Day! Can you guess which decades are which? 👀
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Yesterday, our fearless leader @sgrayg had the opportunity to speak about #DukeMGC's recent work with @cellanome at @MyABRF on the panel 'Optofluidics & CellCages: Approaches for Multimodal #SingleCell Discovery'
Thanks #ABRF26 for the chance to share this groundbreaking work!
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Some members of the Gregory lab spent the weekend enjoying the beautiful cherry blossoms in @DukeGardens and it was picture-perfect!
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April 1 at 12pm, the next installment of the #DukeSCIRIP seminar series, featuring Helen Rueckert & the Gregory lab's Odmaa Bayaraa!
In MSRBIII room 1125 or online via duke.zoom.us/j/91923799748?p…
Want to present? Interested in more info? Visit our webpage: dmpi.duke.edu/duke-single-ce…
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Today, the #DukeMGC is celebrating our 500th @10xGenomics #Xenium sample! From our first run in March of 2023 to now, we've learned a lot and generated data for many publications 🧬
For more info on our #SpatialOmics services, see dmpi.duke.edu/cores/molecula…
#SpatialTranscriptomics
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Presenting the #DukeMGC poster from #AGBT26
'Beyond 'Black Box' Analysis: A platform-agnostic guide for non-formalin fixed #SingleCell RNA sequencing'
For more information, check out our preprint: biorxiv.org/content/10.64898…
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Today, #DukeMGC's Ellora Haukenfrers presented at #DukeSCIRIP 'A platform-agnostic evaluation of non-formalin fixed single cell RNA technologies'
Interested in learning more? Check out our preprint: biorxiv.org/content/10.64898…
Learn more about SCIRIP: dmpi.duke.edu/duke-single-ce…
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Next #DukeSCIRIP seminar is March 4th 12-1pm online or in MSRBIII!
Join us for talks on ongoing research in #SpatialTranscriptomics and #SingleCell at Duke, this month from the Ji lab and #DukeMGC🧬
For more info or to join virtually, please visit dmpi.duke.edu/duke-single-ce…
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Work from the #DukeMGC will be on display at #AGBT2026:
Tuesday 1:30-3:30, poster #401
Wednesday 4:45-6:15, poster #472
Come find us to chat about our data! 🧬
#AGBT #SpatialTranscriptomics #SingleCell #Benchmarking #LongReadSequencing
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We are thrilled to share the 1st pub out of the #DukeMGC. Congrats to Lab Analyst Ellora Haukenfrers on your 1st first author paper!
We present 'A platform-agnostic evaluation of non-formalin fixed #singlecell RNA technologies'
#benchmarking #scRNAseq
biorxiv.org/content/10.64898…
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Upcoming on Feb 4, the next #DukeSCIRIP seminar! Featuring talks from Lauren Parker of the Karra lab & Hamayl Afzal.
For more information or to contact #DukeSCIRIP, please visit out website: dmpi.duke.edu/duke-single-ce…
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That's a wrap on another year in the Gregory lab! 2025 was filled with many hours of hard work in the lab & R Studio, with some fun along the way.
Cheers to 2026 from all of us - we can't wait to show you what we've been working on this year! 🥂🧬🧠
#SingleCell #SpatialOmics
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January 7th 2-1pm in MSRBIII or online, #DukeSCIRIP seminar series continues!
@EpigenomeTech's Chris Hartle will be presenting the talk '‘Deciphering Single-Cell Chromatin Landscapes in the Human Immune System: A First Look’ 🧬
For more information: dmpi.duke.edu/duke-single-ce…
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Yesterday, the Gregory lab had our annual holiday lunch & white elephant gift exchange
A great time was had by all! After all, we have holiday cheer in our DNA (and on our lab cart)🧬🎄🕎
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Today, #DukeMGC gave a talk & poster presentation on our available services at the #Duke Precision Genomics Collaboratory! We love the opportunity to share the work we do... 🧬🧠
Interested in learning more about MGC services? Please visit our website: dmpi.duke.edu/cores/molecula…
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