Antimicrobial resistance, Professor orcid.org/0000-0002-3728-227… AND cans.uit.no/
Tromsø, Norway
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arnfinn sundsfjord retweeted
Things are definitely happening.
An exciting day!
1. The UK 5-year action plan for antimicrobial resistance 2024 to 2029 (tinyurl.com/52tx58ss) has been published today. I am pleased to see that #phage therapy has been named as one of the key solutions for antimicrobial resistance (#AMR) in the report,
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arnfinn sundsfjord retweeted
Prophages block cell surface receptors to ensure survival of their viral progeny biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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arnfinn sundsfjord retweeted
We are excited to share the latest in @npjAMR from @sjmoore505 et al. who developed a synthetic biology strategy to explore @WHO priority pathogen #Klebsiellapneumoniae
This can be used to study #antibiotic target susceptibility and #resistance 💊
(1/5)
nature.com/articles/s44259-0…
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arnfinn sundsfjord retweeted
🧱Thick Cell Walls against Vancomycin 🧱
Adaptive cell wall thickening is associated with decreased vancomycin susceptibility in van-gene negative clinical isolates of E. faecalis
@cans_uit @HegstadKristin @arnfinnss
clinicalmicrobiologyandinfec…
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arnfinn sundsfjord retweeted
Happy 50th birthday bacterial population genetics. It all began with this paper, published 7/12/73 science.org/doi/10.1126/scie…
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arnfinn sundsfjord retweeted
Variation in antibiotic consumption in very preterm infants - supports need to improve antimicrobial stewardship😊 pubmed.ncbi.nlm.nih.gov/3798…
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arnfinn sundsfjord retweeted
Congratulations to @resa_wagner @MonaSusanJohan1 @HegstadKristin and co-authors on their new paper about Enterococcal membrane vesicles as potential vaccine candidates aganst VRE!
💉🦠Enterococcal membrane vesicles as multi-antigen vaccine candidates🦠💉cross-reactive with MDR Efm including VRE.
Great collaboration with @HuebnerJohannes lab!
@cans_uit @MonaSusanJohan1 @HegstadKristin
mdpi.com/1422-0067/24/22/160…
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arnfinn sundsfjord retweeted
🔬 Excited to announce our upcoming hands-on demonstration #MicrofluidicsWorkshop! 🚀 Let's explore the future of precision medicine together! 🧪 #Microfluidics #CellBiology #DrugDiscovery #MicrobialSingleCell #DrugScreening #Marine Biology 🌟
@HiraJonathan
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arnfinn sundsfjord retweeted
Excited to be introducing Single-Cell Phenotypic Profiling and backTracing (CPPT) for dissection of heterogenous growth phenotypes in bacteria. New preprint by co-first authors @HiraJonathan,Bhupender Singh (no X) and team. @MonaSusanJohan1 @cans_uit
biorxiv.org/content/10.1101/…
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arnfinn sundsfjord retweeted
📢 New preprint alert!
Did you know that biofilms can influence the evolution of antimicrobial resistance enzymes?
Our research in Vibrio cholerae unveils how a #biofilm lifestyle shapes the evolution of #β-lactamases.
biorxiv.org/content/10.1101/…
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arnfinn sundsfjord retweeted
Very cool, congrats!
#Efflux is one of the most important #AMR strategies. We discovered that by inducing efflux down-regulation, a newly discovered Burkholderia #phage increases the efficacy of three major #antibiotic classes
biorxiv.org/content/10.1101/…
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arnfinn sundsfjord retweeted
Proud of this work in which Klebsiella helps to uncover new immunology, this time the activation of MAIT cells by type I IFN rupress.org/jem/article/220/… @JExpMed Superb leadership by @BarralLab , a privilege to collaborate with her team.
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arnfinn sundsfjord retweeted
Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens dlvr.it/SsP90y
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arnfinn sundsfjord retweeted
Leveraging AI and machine learning to combat infectious diseases science.org/doi/10.1126/scie…
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arnfinn sundsfjord retweeted
“Phages are one of the most important and yet underappreciated life forms on this planet. The totality of what these viruses do and could do for us is immense.”
thetimes.co.uk/article/e584a…
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arnfinn sundsfjord retweeted
Congratulations for the good work and master thesis, @sabuj_hosen13 ! The first MSc from the @UiTmarine_mbg @UiTNorgesarktis @cans_uit to defend a project fully focused on phages.
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arnfinn sundsfjord retweeted
And here it finally is - despite bioRXiv, acceptance emails, etc; I still get ridiculously excited to see work 'properly' published😊🥳 E. coli carriage in Malawi by the wonderful @joelewis101 @MLW_Programme @KUHeS_mw @LivUni @LSTMnews in @MicrobioSoc MGen microbiologyresearch.org/con…
After quite a bit of additional work on this, here an update on the E. coli part of the story of ESBL carriage in #Malawi; including @catanscombe and Allan Zuza as co-authors; congratulations Allan to his first authorship! @MlwTrust @KUHeS_mw @LSTMnews biorxiv.org/content/10.1101/…
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arnfinn sundsfjord retweeted
Ins and outs of translating phage therapy into the clinic journals.plos.org/plosbiolog…
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arnfinn sundsfjord retweeted
Interested in microbial interactions in the gut?
This resource paper provides an in-depth view of the
metabolic niche of gut microbiome keystone species E. lenta ⬇️⬇️⬇️
@PTurnbaugh
Bacterial #metabolism is important for human health, but most research relies on a few model organisms. @PTurnbaugh &co used a systems biology approach to explore the unusual metabolism of the disease-linked gut bacterium Eggerthella lenta. #microbiology
plos.io/45nrdCH
ALT Heatmap of individual metabolite trajectories in cultures of E. lenta DSM 2243 grown in EDM1 batch culture. Features shown are those whose abundance was significantly different from controls at the final time point.
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arnfinn sundsfjord retweeted
Delighted to see my first PhD paper out in #MGen @MicrobioSoc 🎉
“Within–patient and global evolutionary dynamics of Klebsiella pneumoniae ST17”
doi.org/10.1099/mgen.0.00100…
Explore the dataset interactively in @MyMicroreact microreact.org/project/kpst1…
And read a summary🧵👇
Excited to share the preprint of my first first author paper! We looked at the within-patient and global evolutionary dynamics of Klebsiella pneumoniae ST17 🏥👶🏼🌍 (1/6)
@DrKatHolt @IrenLohr @yekwah @arnfinnss @HakonKaspersen
biorxiv.org/content/10.1101/…
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