There is a child with a rare disease who is currently suffering and struggling to manage his symptoms. Rare as this is, you can directly help him. Today we are launching the "Rare Disease, Real Kid" Hackathon, and there are $50,000 in prizes from @AnthropicAI and @awscloud. We (@huggingface & @Sagebio) are helping this child open his genome and clinical data to the community, so that we can find what's caused his disease and what currently-approved drugs could help him. I doubt I need to motivate this much further or explain how rare it is for a family to share their child's genome and clinical data, but if you're not sure, consider this: Until very recently, it wasn't feasible for patients like this to get treatment because their disease was so rare that the economics could never justify the investment. Now, as we've seen, people with rare diseases are starting to be able to find the answers themselves (with the help of AI tools, cheaper sequencing, etc). This kid is not able to do that for himself and neither are his parents, so we're asking you for help. Both for this kid and to prove that it's possible for everyone else suffering from a rare disease. More details in 🧵. sagebio-rare-disease-real-ki…

hey OpenAI, the rumor is Anthropic has found a cure to cancer... you may want to look into that 😄

We congratulate Levent Alpöge and Tristan Buckmaster on their remarkable mathematical work. We (the researchers and the agents) did not see any of their work through any means until they released it publicly — in particular, no specific user data was accessed in order to solve this problem. While unlikely, we cannot rule out that de-identified data derived from their usage of our products helped improve our models. However, our proofs differ significantly and even the precise results proved are different in the Euler case (forced vs. unforced).

The coolest meeting I had this week with was Paul, who used ChatGPT and other LLMs to create an mRNA vaccine protocol to save his dog Rosie. It is amazing story. "The chat bots empowered me as an individual to act with the power of a research institute - planning, education, troubleshooting, compliance, and yes, real scientific design work in converting genomic data to a vaccine prescription and designing the treatment protocol around it. But they worked alongside humans at every step. The combination is what made it possible." It immediately got me thinking "this should be a company". Also, Paul is an extraordinary guy. This should be easy to do, but it is not yet.

GPT-5 came back with an elegant solution. What struck me: the proof completely bypasses the rich, well-developed theory usually applied to these invariants, instead drawing on techniques from a different corner of algebraic geometry. Sometimes an outsider's perspective helps.

We're now over 900 LoCITT-T participants & close to a last call for new participants! We're still hoping to enroll folks from ND, MS, & PR & more BIPOC participants. More info, lots of FAQs & screening survey here: longcovid.scripps.edu/locitt…

This is fundamentally why decentralization and oipen source are key. Creates an evolutionary-like search across organizations, yielding massive brekathroughs when scaleed.