Prof @Columbia Univ | RNA-Protein Interaction, Neuronal Alternative Splicing, RNA-based Medicine | prev. @RockefellerUniv @CSHL @Tsinghua_Unv | 📢 hiring now

Columbia University, New York, NY
Chaolin Zhang retweeted
Reference-free isoform discovery is here! Torino learns RNA processing events directly from RNA-seq coverage, no annotations required. See how we used it to study isoform evolution and link unannotated isoforms to disease. Led by @cfbuenabad. doi.org/10.64898/2026.10.21.…
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"If the human brain were so simple that we could understand it, we would be so simple that we couldn't." - Emerson M. Pugh (1938)
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Chaolin Zhang retweeted
Online Now: The early RNA decay factor ZC3H18 directs first intron splicing dlvr.it/TVhmqh
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Thrilled to be one of the 25 winners for the @NIH #TRDNT Challenge (Phase 1). 🏆 🏆🏆We will develop an all-in-one #RNA trans-splicing platform for highly efficient and programmable exon editing. We hope to expand the list of druggable target genes that are challenging with current technologies. Kudos to the leading postdoc in the lab Ye Wang for what we have achieved so far! I am very excited about what to expect moving forward! @ColumbiaSysBio @ColumbiaPS @Columbia #RNA #PrecisionMedicine nih.gov/challenges/targeting…
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Chaolin Zhang retweeted
📢 Our Dept. of Systems Biology @Columbia has a faculty opening in the broad area of quantitative biology (Comp/AI/Bio, etc.). Come join our department in NYC! Please circulate/RT. Apply: apply.interfolio.com/192256 Deadline: Nov 1, 2026. @ColumbiaSysBio systemsbiology.columbia.edu/…
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🔥🔥🔥The deadline for abstract submission has been extended to August 28. We still have some spots for short talks (and posters) and look forward to having you join us in Suzhou if you are interested in frontiers of genome biology from either computational or experimental side! 👉 csh-asia.org/?content/3096
Excited to announce the Cold Spring Harbor Asia Conference on Genome Biology: Computation, Technology, and Discovery (Oct. 12–16, Suzhou, China)! I’m delighted to co-organize this meeting again with @cdessimoz, Jing-Dong Jackie Han, and @jmuiuc. We’ll bring together an outstanding group of researchers spanning genomics, AI, computation, and cutting-edge technology development to the beautiful garden city 30 min from Shanghai by high-speed train. 📅 Abstract deadline: Aug. 7 (just over 2 weeks away) Please RT! csh-asia.org/?content/3096 @CSHANews
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Excited to announce the Cold Spring Harbor Asia Conference on Genome Biology: Computation, Technology, and Discovery (Oct. 12–16, Suzhou, China)! I’m delighted to co-organize this meeting again with @cdessimoz, Jing-Dong Jackie Han, and @jmuiuc. We’ll bring together an outstanding group of researchers spanning genomics, AI, computation, and cutting-edge technology development to the beautiful garden city 30 min from Shanghai by high-speed train. 📅 Abstract deadline: Aug. 7 (just over 2 weeks away) Please RT! csh-asia.org/?content/3096 @CSHANews
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Many short talks will be selected from submitted abstracts. If you have exciting new and unpublished work in genomics, computational biology, AI, single-cell biology, RNA biology, functional genomics, or related areas, we’d love to receive your abstract.
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We especially encourage submissions from graduate students, postdocs, and junior faculty. Selected trainee presentations are eligible for travel fellowships (USD $100–500). We look forward to seeing you in beautiful Suzhou this October! 🗓️ Abstract deadline: Aug. 7 Please share with your lab members and colleagues!
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Many short talks will be selected from submitted abstracts. If you have exciting new and unpublished work in genomics, computational biology, AI, single-cell biology, RNA biology, functional genomics, or related areas, we’d love to receive your abstract.
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We especially encourage submissions from graduate students, postdocs, and junior faculty. Selected trainee presentations are eligible for travel fellowships (USD $100–500). We look forward to seeing you in beautiful Suzhou this October! 🗓️ Abstract deadline: Aug. 7 Please share with your lab members and colleagues!
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The “it corrupts science” argument for not paying peer reviewers by for-profit journals is like … “you can’t pay lawyers because it corrupts justice”. $290 per review is a good starting point, but I would argue that 1/3 of the gross revenue should be directed to peer reviewers, or about $600 per review (based on publication fee of OA journals). This is still a very low rate as a lawyer easily charges $1000-2000 per hour. 1/ nature.com/articles/d41586-0…
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Also on preprints, open access, journal names ... Academic publications serve two purposes: dissemination of knowledge and endorsement of quality/impact. The two puroposes are used to realize in the same process - publication in a journal (or conference for some fields like CS) at different tiers. Now it is quite possible that the two aspects will be separated (preprint before formal peer review & publication). No one would deny that timely dissemination of knowledge is critical for advance of science, so the value of preprint. Some of the efforts argue against the different journal names as endorsement of quality (denial of prestige). People say only long lasting science is good science. This is certainly true, but practically speaking, it is not obvious what is the better approach for a short term evaluation of science by expert peer reviewers. Why is this necessary? Imagine when you evaluate hundreds of job candidates or grant proposals, and you would have to read all the original preprints! I guess the importance/value of branding is not a new idea in the business world, and paradoxically one has never seen the level of self promotion/branding we have on social media today ... 2/
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We are close when a discovery is made by AI but without AI in the title of the publication?
Jennifer is spot on as always. Biology is hard and the solutions aren’t simply buried in the literature. Not to mention, a significant proportion of the literature is wrong or highly biased.
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Chaolin Zhang retweeted
news.columbia.edu/news/colum… For those that loose faith in the value of academic, government-funded research, this list provides a nice example of how the pursue of knowledge improves and saves lives!
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Chaolin Zhang retweeted
New paper! How do RNAs "know" where to go inside a cell? We dug into the sequence elements that route RNAs to the right place. It turns out that, in mammals, they're surprisingly massive (>200 nt), multipartite, and wonderfully complicated. đź§µ
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