Research group @BUChemistry interested in catalysis, organic synthesis, organometallic chemistry, and electrochemical methods.
- Tweets 108
- Following 73
- Followers 907
- Likes 106
Pinned Tweet
New preprint in collaboration w/ the Gutierrez lab! ⚡️
A single phenyl group on ferrocene only shifts redox potential by 20 mV, yet can dramatically change its performance through proposed substrate-mediator π-interactions in Shono-type allylation.
chemrxiv.org/doi/full/10.264…
2
3
22
3,095
Excited to share our latest preprint from the Derosa Lab and Gutierrez Lab, where we report an electrocatalytic strategy for E-selective alkyne semi-hydrogenation using tandem electrocatalysis.
Preprint: chemrxiv.org/doi/full/10.264…
1
7
50
2,877
Congrats to @Yahuiiiiiiii and Siyuan on their Perspective in ACS Electrochemistry! We highlight strategies over the last ~10 years in Shono-type functionalization from tunable conditions to mediators, outlining exciting prospects for further development.
pubs.acs.org/doi/full/10.102…
1
12
63
3,198
Derosa Lab retweeted
This is a really nice example of selectivity emerging from constraint, not just energetics.
The Co–O–C interaction looks less like a secondary stabilisation and more like a geometric gate in configuration space, effectively collapsing the accessible pathways so the Z-product becomes the only coherent reconstruction.
In that light, the DFT isn’t just explaining selectivity after the fact; it’s revealing a structure-first control mechanism, where redox mediation and MS-PCET act to maintain the constraint rather than drive the outcome.
That’s an interesting direction for thinking about scalability and robustness in catalytic design.
@derosalab @uclachem @ACSCatalysis
We are thrilled to see our collaborative work with the Gutierrez group at @uclachem published in @ACSCatalysis today! Congrats to @bryanparnitzke and team on an impressive study! More to come in this area soon, building on exciting mechanistic insights.
pubs.acs.org/doi/10.1021/acs…
3
5
27
1,805
We are thrilled to see our collaborative work with the Gutierrez group at @uclachem published in @ACSCatalysis today! Congrats to @bryanparnitzke and team on an impressive study! More to come in this area soon, building on exciting mechanistic insights.
pubs.acs.org/doi/10.1021/acs…
3
11
87
6,407
Congrats to Brett and Jillian on their e-SNAr strategy to enable azolation of electron-rich fluoroarenes now published in @angew_chem at a "Hot Paper"! Simple, scalable, and energy efficient - with new strategies to expand scope underway! #chemtwitter
onlinelibrary.wiley.com/doi/…
1
7
80
12,013
Derosa Lab retweeted
Fantastic visit at @UniofNottingham School of Chemistry today sharing some of our recent work in @derosalab using voltage control to enable selective electrosynthesis and catalysis. Thanks to @miriamoduill for the gracious hosting and organizing great discussions with faculty!
3
34
2,861
Congrats to Zi and team on the publication of our study on a redox mediator strategy to electroreductively harness Fe(I) in alkyne semi-hydrogenation! This work is now published in @ACSCatalysis - stay tuned for more from #TeamFe. #chemtwitter #newPI
pubs.acs.org/doi/10.1021/acs…
1
11
70
4,480
We are grateful to the @acsprf for funding our proposal on arene functionalization strategies for upconversion of aromatic feedstocks!
Congrats to all the awardees this cycle: cen.acs.org/acs-news/ACS-Boa…
3
2
47
4,744
Derosa Lab retweeted
Congrats to Brett and Jillian on this incredibly powerful e-SNAr strategy! Synthetically enabling, extremely robust, and highly energy-efficient with as low as 20 mW of power at 50 mmol scale with a proposed uphill ET-promoted redox chain mechanism. Dump, stir, ⚡️ #chemtwitter
SNAr powers the engine of drug discovery and production, but electronic demands restrict access to important chemical space. We describe an e-SNAr strategy to bridge this gap that operates under air at RT with catalytic charge, simplifying scalability.
chemrxiv.org/engage/chemrxiv…
4
47
5,113
SNAr powers the engine of drug discovery and production, but electronic demands restrict access to important chemical space. We describe an e-SNAr strategy to bridge this gap that operates under air at RT with catalytic charge, simplifying scalability.
chemrxiv.org/engage/chemrxiv…
1
13
73
10,922
Harnessing reduced Fe in electrocatalysis faces many challenges with respect over-reduction and catalyst instability. In this preprint, we describe a redox mediator strategy to tame a (P3P)Fe(I) species for semi-hydrogenation of alkynes as a model study:
chemrxiv.org/engage/chemrxiv…
3
10
75
7,459
Huge congrats to our very own @bryanparnitzke for being awarded the NSF Graduate Research Fellowship! We are so proud of you! 🎉🥳 #chemtwitter #nsfgrfp
1
1
51
3,914
San Diego, here we come! For anyone interested in what we've been up to, please consider stopping by one of our talks next week at ACS Spring 2025! #ACSSpring2025 #chemtwitter
1
3
53
6,254
Congrats to Bryan on a fantastic qualifying examination! We are so proud of you! #newPI #phdlife #chemtwitter
2
3
79
7,352
Derosa Lab retweeted
SAXITOXIN simplified: Appearing today in @ChemRxiv is a short, highly scalable, convergent approach to this entire natural product family using a tactical combination of radical retrosynthesis, biocatalysis (in collaboration with Merck), and C–H functionalization logic: chemrxiv.org/engage/chemrxiv…
3
59
338
62,923
With the Gutierrez group @UCLA , we report a unique mode of electrocatalytic semi-hydrogenation to generate Z-alkenes using a redox mediator strategy. Distortion analyses by DFT reveal a distinct origin of stereoselectivity. Exciting times ahead!
chemrxiv.org/engage/chemrxiv…
3
7
43
11,502
