geriatrician, eFI, CARE75+, HERO trial, PROSPER study
Yorkshire
- Tweets 3,377
- Following 725
- Followers 2,346
- Likes 4,935
Andrew Clegg retweeted
The primary care network, Affinity Care, had its research capacity boosted by our wider care settings funding.
You can apply for wider care settings funding now for your project.
Visit our website to find out more and apply 👇
nihr.ac.uk/support-and-servi…
3
3
598
Andrew Clegg retweeted
Frailty should not be a barrier to AD disease-mod-treatments—it can be a clinical compass. 🧭🧠 Our new paper proposes a frailty-informed, person-centred approach to AD-DMT decision-making. authors.elsevier.com/sd/arti… @drandyclegg @M_SuarezCalvet
@alessandro5161 @SusanShenkin
1
3
82
Andrew Clegg retweeted
“The eFI helped us identify the right patients. Using SystmOne, we were then able to bring the right professionals around those patients, coordinate actions and track outcomes.” – Dr Danielle Nimmons, Academic GP and Clinical Director.
SystmOne is connecting professionals in Spen Valley across organisational boundaries, supporting shared pathways and joined-up neighbourhood care.
🖥️ One shared #SystmOne record gives professionals a structured view of discussions, risks, actions, care goals and outcomes.
🔗 Read more: tpp-uk.com/news/from-frailty…
#IntegratedNeighbourhoodTeams #Frailty #PrimaryCare #DigitalHealth
1
3
358
Andrew Clegg retweeted
🚨 The 2026 @escardio #HeartFailure Guidelines are here❗️#ESCcongress @secardiologia
1) HFmrEF is gone.
Acute HF is gone.
NT-proBNP cut-offs are now age-adjusted.
Everything that matters 🧵👇
2/ 🔄 NEW DEFINITION — two phenotypes only
❤️🩹 HFrEF → LVEF <50% + symptoms/signs
🫀 HFpEF → LVEF ≥50% + symptoms/signs + objective evidence of structural/functional abnormality
❌ HFmrEF eliminated: same aetiology, same pathophysiology, same treatment response as HFrEF
7
250
568
42,819
Andrew Clegg retweeted
The Anticholinergic Medication Index (ACMI) is a new measure of anticholinergic burden, developed using a large dataset of UK patients.
A patient’s ACMI score represents their cumulative anticholinergic burden: higher ACMI indicates stronger association with delirium and falls.
1
2
2
148
Andrew Clegg retweeted
Honoured to share my latest Clinical Practice review, "Syncope," published today in the New England Journal of Medicine.
Syncope is a common clinical problem caused by transient cerebral hypoperfusion and encompasses reflex, orthostatic, and cardiac mechanisms. Accurate diagnosis relies on careful history taking and physical examination, as well as targeted test ing guided by risk stratification. Management of syncope is determined on the basis of the underlying mechanism and focuses on reducing recurrence and injury risk. In older patients, syncope may manifest as unexplained falls. Early identifica tion of high-risk features is critical to prevent adverse cardiovascular outcomes.
I'm grateful to the @NEJM for the opportunity to contribute to this important area of clinical practice.
A new Clinical Practice article summarizes the classification, evaluation, risk stratification, and management of syncope. History, examination, electrocardiography, and orthostatic blood-pressure measurement identify the cause in most patients.
Read “Syncope” by Rose Anne Kenny, MD, DSc: nej.md/4cjFuVU
Ask AI Companion to provide a summary of this article for your patient. In Spanish.
ALT A flowchart from the Clinical Practice article "Syncope" by Rose Anne Kenny, M.D., D.Sc., that shows the general principles for initial evaluation of all patients after an episode of syncope. The chart includes steps such as suspected syncope, evaluation, history taking, and an ECG. It categorizes causes of syncope as certain or uncertain, leading to risk assessment and further evaluation or treatment.
2
9
27
3,753
Andrew Clegg retweeted
NHS England recently announced an accelerated rollout of AI, including a new AI triage tool on the NHS app.
AI might help the NHS, but we need to build the evidence, say Mary Dixon-Woods and colleagues
bmj.com/content/394/bmj-2026…
1
14
20
10,529
Andrew Clegg retweeted
… & now #FINDHF
Scalable risk stratification of undiagnosed #heartfailure using routine health data & its association with imaging phenotypes & outcomes nature.com/articles/s41598-0…
4
8
825
Andrew Clegg retweeted
Celebrating #NIHR20 anniversary🎉 Thank you @NIHRresearch for 20 years of incredible support for ageing and stroke research 👏
Your commitment continues to drive innovation and improve lives!
@BTHFT @CityOfResearch @drandyclegg
4
6
190
Andrew Clegg retweeted
This may be the greatest 2 minutes and 44 seconds of television I’ve ever seen
Politics UK
302
1,936
15,456
1,733,065
Andrew Clegg retweeted
From today 10 NIHR Applied Research Collaborations (ARCs) will be delivering applied health and care research across England. They will be developing new treatments and technologies and supporting Government health plans. 👇
🔗 nihr.ac.uk/about-us/what-we-…
9
16
1,549
Andrew Clegg retweeted
🚀 The next phase of @NIHR_ARC_YH starts NOW
One priority: IMPACT
Research that transforms. Partnerships that deliver. Change where it's needed most. 💙 Let's make this next phase a powerful force for positive change.
#ARCYorkshireHumber #HealthResearch #NIHR #NIHR20
4
3
184
Andrew Clegg retweeted
A really meaningful day at the Leeds BME Dementia Forum 2026 💛
Together with partners, we brought together 60+ people from diverse local communities, with 15 organisations involved.
Listening, sharing, and connecting.
@NIHR_ARC_YH, @alzheimerssoc @TBmedementia, @AUASResearch
1
2
144
Andrew Clegg retweeted
I was so pleased to be part of a great team writing a commentary on the draft FDA guidelines on Bayesian clinical trial designs. Should have been done 30 years ago, but better late than never
💬 Perspective: Bayesian methodology supports efficient, flexible clinical trial designs; FDA guidance encourages prespecification and sensitivity analysis of priors.
@f2harrell @d_spiegel
ja.ma/47hHTyb
4
76
289
48,555
Andrew Clegg retweeted
We’ve announced the latest cohort of NIHR Senior Investigators, reflecting the breadth of modern research leadership.
For the first time, the cohort includes two senior research leaders from Northern Ireland, alongside increased representation from post-1992 universities.
Senior Investigators are among NIHR’s most influential researchers, driving innovation, mentoring future leaders, and shaping policy and practice.
Learn more about this year's cohort.👉nihr.ac.uk/news/new-nihr-sen…
ALT We’ve announced the latest cohort of NIHR Senior Investigators, reflecting the breadth of modern research leadership.
6
16
5,029
Andrew Clegg retweeted
HERO trial results published in Age & Ageing: doi.org/10.1093/ageing/afag0….
Extended rehab after acute hospital admission for older people with frailty: Reduced hospital admissions over 12 months, but did not impact measures of function or health related quality of life.
4
6
240
Andrew Clegg retweeted
That's a wrap on a brilliant day in York! 🏛️ Thank you to all our speakers, chairs and attendees for a thought-provoking event on the future of mental health prevention in the NHS. #JourneyToPrevention2026 #NIHRYHARC
3
3
237
Andrew Clegg retweeted
The modified Richmond Agitation and Sedation Scale (mRASS)
For ongoing monitoring for new onset #delirium in inpatients.
2
5
23
759
Andrew Clegg retweeted
Really pleased to see this paper published. It should be a helpful read for anyone considering starting a clinical academic career through a post such as an ACF (not the only route into research), those currently in post, and also for supervisors/funders supporting these roles.
#OriginalResearch
📄 Balancing act of academic clinical fellows in UK emergency medicine: a qualitative study
emj.bmj.com/content/early/20…
Clinical academia is essential for advancing emergency care, but how do trainees actually experience early academic pathways in EM?
🔍 What this study explored
Using semi-structured interviews with 20 current and former EM ACFs across England and Wales, the authors examined how fellows navigate the balance between clinical training and research.
💡 Key findings
• Structural ambiguity and unclear expectations within programmes
• Variable supervision and limited direction early in posts
• Professional isolation and challenges integrating with clinical teams
• Difficulty balancing clinical competencies with academic work
• EM-specific barriers including limited mentorship and reduced exposure to key rotations
• Positive experiences linked to strong supervision, research alignment, and supportive networks
📌 Why this matters
The study highlights the need for:
✅ Standardised induction and clearer training pathways
✅ Consistent supervision and mentorship
✅ Transparent programme structures
✅ Better support to sustain the future EM clinical academic workforce
For those involved in EM training, workforce development, or clinical academic pathways, this paper provides valuable insight into improving how we support early career researchers.
What are your experiences of academic training in emergency medicine or other specialties?
@richardbody @RCollEM @EMergeMedGlobal @clifford0584 @vfjn2
#EmergencyMedicine #MedicalEducation #ClinicalAcademia #HealthProfessionsEducation #Research #EMTraining #WorkforceDevelopment
2
5
856
Andrew Clegg retweeted
2/6 Professor Elizabeth Orton, Theme Lead and Consultant in Public Health
Practical steps to commission and expand Falls Management Exercise (FaME) despite complex funding systems. Proven to reduce falls.
Read here:
🔗 arc-em.nihr.ac.uk/news/achie…
1
2
3
134