I just saw a patient with UNSTEADY WALK & alcohol-related liver disease. I always assess these 4 factors:
• Sarcopenia
• Peripheral neuropathy
• Vitamin B12 deficiency
• Cerebellar atrophy
This figure summarizes my approach:
🏀 Next up: The NEW MASLD Treatment Era
@JazminMexia explores combination metabolic therapy, real-world resmetirom use, and quality of life.
New treatments are reaching patients—but what do the results show?
Thread 👇 #HepMadness2026
What are the controversies we need to solve that face US patients with cirrhosis? Join us in Miami in January
ACES-Summit.org
Organized by O’Leary, @serperm, @JasmohanBajaj, and myself, we hope you join us to build better evidence and better strategies for our patients
🏀 Next up: AI in the Clinic and at the Bedside
@drnakulganju explores AI that finds missed MASLD, drafts hepatology e-consults, and answers drug-induced liver injury questions.
Can liver-specific AI make a championship run? 👇 #HepMadness2026
In the next #TalkLiverToMe, experts revisit the fundamentals of hepatocellular carcinoma surveillance, with a practical look at patient selection, timing and the modalities available for early detection.
Tune in this Wednesday on your Spotify, Apple Podcasts or EASL Campus to listen to this interactive discussion.
More information: easl.eu/event/hepatocellular…
📑 The symptom burden of #PBC is substantial‼️
🚨Fatigue: 51%
🚨Pruritus: 33%
🚨Severe Pruritus: 10%
⚠️Yet only 36% of patients with pruritus received treatment❕
⭐️PBC care must extend beyond biochemical response❕
#LiverX#OpenAccessjournals.lww.com/hepcomm/ful…
One of the (but certainly not THE) greatest feelings in academia is seeing your findings reproduced. Several years ago with Amit and Neehar I was the programmer for a cost-effectiveness analysis. We estimated that in real world settings, the incidence of HCC at which it becomes
How to read a cost-effectiveness paper
This is a powerful method. But poorly understood, often maligned. My goal is to improve critical appraisal and help good analyses get the appreciation they deserve
🧵#MedTwitter CEA: cost-effectiveness analysis
I once did a cost effectiveness analysis comparing shotgun vs deliberate testing for elevated ALT
pubmed.ncbi.nlm.nih.gov/2771…@JHepatology
We found that broad testing didn’t add much costs but increased false positives, especially when pretest probability of NAFLD was high
How to read a cost-effectiveness paper
This is a powerful method. But poorly understood, often maligned. My goal is to improve critical appraisal and help good analyses get the appreciation they deserve
🧵#MedTwitter CEA: cost-effectiveness analysis
MELD tells us how sick the liver is. The #LiverFrailtyIndex tells us how sick the patient is.
But LFI needs an in-person exam.
New in @LTxJournal: the Lab-LFI. 7 proteins, c-stat 0.80 for predicting frailty in cirrhosis.
Read it here: ovid.com/jnls/lt/fulltext/10…
🏀 Next up: Falls, Frailty, and Sarcopenia
Sirisha Gaddipati explores how physical frailty, muscle loss, and fall risk affect outcomes in cirrhosis.
Can this theme stand strong through the competition? 👇 #HepMadness2026