We are simultaneously ramping into the singularity & seeing odd investor interest for non-exponential companies

Gritty people have passion and perseverance because their interests absorb them, their work leads them to experience flow, and they believe their work has a purpose. However, their path to excellence is more than just logging more hours of practice. They log more hours of deliberate practice. They set stretch goals, dedicate themselves to achieving them, ask for critical feedback to improve, and when finished with one goal, they repeat with another stretch goal. Extraordinary achievement is the stringing together of many ordinary achievements of smaller stretch goals along the way. It is about perseverance over adversity and simply getting up every day for deliberate practice until you finish the season. It is not that gritty people never quit. But, gritty people don't quit on a bad day.

one of the greatest public data drops of all time - this is what bringing transparency to healthcare looks like

Awesome stuff

Preprint out today that tests o1-preview's medical reasoning experiments against a baseline of 100s of clinicians. In this case the title says it all: Superhuman performance of a large language model on the reasoning tasks of a physician Link: arxiv.org/abs/2412.10849 A 🧵⬇️

A story of two incredible, incredible humans. Highly encourage you to watch on Amazon Prime video! @bsw5020 & @sabrevaya thank you for sharing your powerful, heartbreaking, and inspiring story. You’ve shown the world what it means to do something bigger than one’s selves. The ALS community is so lucky to have you

When Brian Wallach was diagnosed with ALS, he was given six months to live. @bsw5020 and @sabrevaya’s film, For Love & Life: No Ordinary Campaign, chronicles their incredible journey, and proves that all of us are far more powerful than we know. I hope you’ll watch it on Prime Video and get involved with their work to find a cure for ALS at IAmALS.org.

Fourteen years ago today, I signed the Affordable Care Act into law. Afterwards, one Republican member of the House called the ACA the “most dangerous piece of legislation ever passed in Congress.” Another predicted the country would “never recover from it.” But then something else happened: it actually worked.

Interested in the buying and selling patterns for digital health in oncology, or how AI is impacting investment in the space? Check out our latest installment of Flare Capital's Expert Roundtable Series on Oncology below. flarecapitalpartners.medium.…

my brother founded a unicorn, ran it well for a long time, is an extremely accomplished investor, is terrible at all video games, and can only squat about 150 pounds. maybe "unicorn founder jack altman" would be a more reasonable way to introduce him?

Cell therapies are coming under fire this morning. FDA is seeking box label warnings for all 6 approved CAR-T cell therapies. Previous guidance was issued for Legend Biotech and Janssen’s myeloma CAR-T therapies, citing secondary blood cancers following treatment (Dec 21, 2023).

I don’t know if I am more impressed or more upset about the Steelers this year. No offense, but somehow we continue to pull off wins against good teams. No one would consider them a true Super Bowl contender… Very confusing

I’ve spent a lot of time recently thinking through the shift towards value-based *specialty* care for highly variable patient populations (neuro, onco). The shift will be very slow, but we shouldn’t avoid thinking through ways to engage payers/providers. Breakthroughs are coming

We are thrilled to announce our investment in Visana Health!! We are honored to continue supporting @JConnol and the entire Visana team — as they continue to use technology to build a clinically rigorous women’s health company. @vlan8 @uma_veerappan medium.com/p/-167b46b16ed7

A lot of similarities to the recent ADHD drug spike which saw tightened regulation and “bad actors” that came to light. Completely different use cases but still.. Is this GLP-1 administration really sustainable? Providers must be thoughtful in the delivery of these drugs

Happy fourth everyone 🇺🇸 Proud to be an American today and every day. Land of the free, home of the brave