Can we design molecules that rewrite how organisms interact with the environment? I'm delighted to share our lab's latest work, where we use structural biology and chemistry to modulate insect behavior in a clade of destructive agricultural pests. Congrats Steve and team!
Excited to share our updated preprint on moth pheromone reception!
Can we leverage structure-based pharmacology to disrupt insect olfactory behavior?
We designed small molecule inhibitors that hijack moth pheromone receptors to block mate recognition. A thread: