Translating AI into healthcare through ethical and trustworthy machine learning; Editorial Board @npjDigitalMed.

Singapore
๐ŸŒ๐— ๐—ฒ๐—ฑ๐—ถ๐—ฐ๐—ฎ๐—น ๐—”๐—œ ๐˜€๐—ต๐—ผ๐˜‚๐—น๐—ฑ ๐—ฏ๐—ฒ ๐—ฒ๐˜ƒ๐—ฎ๐—น๐˜‚๐—ฎ๐˜๐—ฒ๐—ฑ ๐—ถ๐—ป ๐˜๐—ต๐—ฒ ๐—น๐—ฎ๐—ป๐—ด๐˜‚๐—ฎ๐—ด๐—ฒ๐˜€, ๐—ฐ๐—ผ๐—บ๐—บ๐˜‚๐—ป๐—ถ๐˜๐—ถ๐—ฒ๐˜€ ๐—ฎ๐—ป๐—ฑ ๐—ต๐—ฒ๐—ฎ๐—น๐˜๐—ต ๐˜€๐˜†๐˜€๐˜๐—ฒ๐—บ๐˜€ ๐˜„๐—ต๐—ฒ๐—ฟ๐—ฒ ๐—ถ๐˜ ๐˜„๐—ถ๐—น๐—น ๐—ฎ๐—ฐ๐˜๐˜‚๐—ฎ๐—น๐—น๐˜† ๐—ฏ๐—ฒ ๐˜‚๐˜€๐—ฒ๐—ฑ. Delighted to announce the launch of #MAGIC (๐— ๐—ฒ๐—ฑ๐—ถ๐—ฐ๐—ฎ๐—น ๐—”๐—œ ๐—š๐—น๐—ผ๐—ฏ๐—ฎ๐—น ๐—œ๐—ป๐—ถ๐˜๐—ถ๐—ฎ๐˜๐—ถ๐˜ƒ๐—ฒ ๐—ฎ๐—ป๐—ฑ ๐—–๐—ผ๐—น๐—น๐—ฎ๐—ฏ๐—ผ๐—ฟ๐—ฎ๐˜๐—ถ๐—ผ๐—ป) introduced in our new @NaturePortfolio @NatureMedicine correspondence. ๐Ÿ“œMAGIC paper: nature.com/articles/s41591-0โ€ฆ ๐Ÿ”—MAGIC website: magic-ai.health/ MAGIC brings together clinicians, AI researchers, policymakers, industry stakeholders and local experts to address a critical question: does strong benchmark performance translate into safe, useful support across diverse healthcare settings? Our initial priorities are: โœ… A global health LLM evaluation benchmark addressing multilingual coverage, regional disease burden and sociocultural adaptability. โœ… A global deployment reporting standard clarifying intended use, target users, healthcare settings, and performance and safety across populations. Thank you to our colleagues #worldwide for helping launch the network. ๐—ข๐˜‚๐—ฟ ๐—ด๐—ผ๐—ฎ๐—น ๐—ถ๐˜€ ๐˜๐—ผ ๐˜‚๐—ป๐—ฑ๐—ฒ๐—ฟ๐˜€๐˜๐—ฎ๐—ป๐—ฑ ๐˜„๐—ต๐—ฒ๐—ฟ๐—ฒ ๐—บ๐—ฒ๐—ฑ๐—ถ๐—ฐ๐—ฎ๐—น ๐—”๐—œ ๐˜„๐—ผ๐—ฟ๐—ธ๐˜€, ๐—ณ๐—ผ๐—ฟ ๐˜„๐—ต๐—ผ๐—บ, ๐—ฎ๐—ป๐—ฑ ๐˜‚๐—ป๐—ฑ๐—ฒ๐—ฟ ๐˜„๐—ต๐—ฎ๐˜ ๐—ฐ๐—ผ๐—ป๐—ฑ๐—ถ๐˜๐—ถ๐—ผ๐—ป๐˜€. #MAGIC #MedicalAI #AI #LLM #GlobalHealth #ResponsibleAI #HealthEquity #DukeNUS @dukenus
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Honored to be ๐—ฟ๐—ฎ๐—ป๐—ธ๐—ฒ๐—ฑ ๐Ÿฎ๐Ÿญ๐Ÿฌ๐˜๐—ต ๐—ด๐—น๐—ผ๐—ฏ๐—ฎ๐—น๐—น๐˜† (๐—ฎ๐—บ๐—ผ๐—ป๐—ด ๐˜๐—ต๐—ฒ ๐˜๐—ผ๐—ฝ ๐Ÿฌ.๐Ÿฌ๐Ÿฑ% ๐˜„๐—ผ๐—ฟ๐—น๐—ฑ๐˜„๐—ถ๐—ฑ๐—ฒ) in the ScholarGPS 2026 Highly Ranked Scholars โ€“ Lifetime rankings (Machine Learning specialty). This recognition is a reflection of the collective effort behind our work. My sincere thanks to every member of the ๐——๐—ถ๐—ด๐—ถ๐˜๐—ฎ๐—น ๐— ๐—ฒ๐—ฑ๐—ถ๐—ฐ๐—ถ๐—ป๐—ฒ ๐—Ÿ๐—ฎ๐—ฏ and to our collaborators around the world. #MachineLearning #MedicalInformatics #AI #ResponsibleAI #TrustworthyAI #DigitalHealth #ResearchImpact #DukeNUS
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๐—˜๐˜๐—ต๐—ถ๐—ฐ๐˜€ ๐—ถ๐—ป ๐—ต๐—ฒ๐—ฎ๐—น๐˜๐—ต ๐—”๐—œ ๐—ฐ๐—ฎ๐—ป๐—ป๐—ผ๐˜ ๐—ฏ๐—ฒ ๐—ฎ ๐—ณ๐—ถ๐—ป๐—ฎ๐—น ๐—ฐ๐—ต๐—ฒ๐—ฐ๐—ธ๐—ฏ๐—ผ๐˜… ๐—ฏ๐—ฒ๐—ณ๐—ผ๐—ฟ๐—ฒ ๐—ฑ๐—ฒ๐—ฝ๐—น๐—ผ๐˜†๐—บ๐—ฒ๐—ป๐˜. Sharing our new article in @Patterns_CP: "Ethical principles and considerations in health AI." Our central argument: ethical principles should guide the entire #AI #lifecycle, from development and validation to deployment and ongoing monitoring, and must be considered together, not in isolation. We highlight three practical points, among many others: โœ… ๐—˜๐˜๐—ต๐—ถ๐—ฐ๐—ฎ๐—น ๐—ฝ๐—ฟ๐—ถ๐—ป๐—ฐ๐—ถ๐—ฝ๐—น๐—ฒ๐˜€ ๐—ถ๐—ป๐˜๐—ฒ๐—ฟ๐—ฎ๐—ฐ๐˜. Efforts to improve equity can create trade-offs with predictive performance, requiring careful assessment of safety and alternative safeguards. โœ… ๐—ง๐—ฟ๐—ฎ๐—ป๐˜€๐—ฝ๐—ฎ๐—ฟ๐—ฒ๐—ป๐—ฐ๐˜† ๐—ป๐—ฒ๐—ฒ๐—ฑ๐˜€ ๐—ฎ ๐—ฝ๐˜‚๐—ฟ๐—ฝ๐—ผ๐˜€๐—ฒ. Clinicians need evidence about local performance, uncertainty and limitations, not just model explanations, to decide when to follow, question or override AI. โœ… ๐—–๐—ผ๐—ป๐˜๐—ฒ๐˜…๐˜ ๐—บ๐—ฎ๐˜๐˜๐—ฒ๐—ฟ๐˜€. Clinical priorities and available resources shape which safeguards are feasible, particularly in low-resource settings. This is not another checklist. It is an approach to understanding how ethical principles interact and translating them into decisions at the model, workflow and health-system levels. Thank you to our international team for this collaboration. ๐—ข๐˜‚๐—ฟ ๐—ด๐—ผ๐—ฎ๐—น ๐—ถ๐˜€ ๐˜๐—ผ ๐—บ๐—ฎ๐—ธ๐—ฒ ๐—ฒ๐˜๐—ต๐—ถ๐—ฐ๐˜€ ๐—ฎ๐—ป ๐—ผ๐—ป๐—ด๐—ผ๐—ถ๐—ป๐—ด ๐—ฝ๐—ฎ๐—ฟ๐˜ ๐—ผ๐—ณ ๐—ต๐—ผ๐˜„ ๐—ต๐—ฒ๐—ฎ๐—น๐˜๐—ต ๐—”๐—œ ๐—ถ๐˜€ ๐—ฏ๐˜‚๐—ถ๐—น๐˜, ๐—ฒ๐˜ƒ๐—ฎ๐—น๐˜‚๐—ฎ๐˜๐—ฒ๐—ฑ ๐—ฎ๐—ป๐—ฑ ๐˜‚๐˜€๐—ฒ๐—ฑ, ๐—ป๐—ผ๐˜ ๐—ฎ๐—ป ๐—ฎ๐—ณ๐˜๐—ฒ๐—ฟ๐˜๐—ต๐—ผ๐˜‚๐—ด๐—ต๐˜. ๐Ÿ“– Read open-access paper: doi.org/10.1016/j.patter.202โ€ฆ #AI #Ethics #ResponsibleAI #HealthAI #AIEthics #TrustworthyAI #DigitalHealth #DukeNUS @CellPressNews
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Glad to be included again in the 2026 World's Top 2% Scientists list (Stanford & Elsevier), and heartened to be ranked 122 among 22,436 researchers in Medical Informatics, my primary research field. While this recognition is encouraging, citations are not the purpose of our work. What matters most is conducting meaningful research, addressing real healthcare needs, and contributing to the communities we serve. Look forward to continuing our work on trustworthy and responsible AI for healthcare, with clinical value, patient well-being and community benefit at its heart. #MedicalInformatics #ResponsibleAI #TrustworthyAI #AI #LLM #DigitalHealth #ResearchImpact #DukeNUS
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๐ŸŒThe global #AI divide in healthcare is widening, and privacy laws are part of why. Sharing our new article in @NaturePortfolio @npjDigitalMed. The core problem: clinical AI is trained mostly on data from high-resource settings, while low-resource settings, which carry the greatest disease burden, remain underrepresented. Pooling global data could be a fix to this. But privacy regulations, data sovereignty concerns, and the risk of "digital colonialism" mean that data often cannot move across borders. It's a deadlock: local performance needs diverse data, but privacy concerns keep that data locked in place. Privacy-enhancing technologies (#PETs) such as de-identification, synthetic data, federated learning, and cryptographic methods, could offer a way through, shifting the paradigm from data-sharing to knowledge-sharing. But not all PETs are equally deployable. In resource-constrained settings, techniques like statistics-based federated learning and transfer learning are more feasible than computationally expensive approaches like homomorphic encryption. The rise of #LLMs adds new urgency, and new risks, to this picture. Real progress requires more than good algorithms. We outline four pathways: 1) data governance built on sovereignty rather than extraction, 2) harmonized model-sharing guidelines, 3) accessible/lightweight infrastructure, and 4) trust-based partnerships. ๐Ÿ“œ Read paper here: nature.com/articles/s41746-0โ€ฆ #GlobalHealth #DigitalHealth #AI #HealthEquity #PrivacyEnhancingTechnologies #FederatedLearning #HealthAI #DataGovernance #LMIC #ResponsibleAI #DukeNUS
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[๐ŸŒ๐—”๐—œ ๐—š๐—ผ๐˜ƒ๐—ฒ๐—ฟ๐—ป๐—ฎ๐—ป๐—ฐ๐—ฒ & ๐—ฃ๐—ผ๐—น๐—ถ๐—ฐ๐˜† ๐—–๐—ผ๐—ฟ๐—ป๐—ฒ๐—ฟ] A healthcare AI model can be accurate when tested and still be unreliable when used. Why? Because clinical reliability is not a fixed property of a model. It depends on which patients encounter it, where and how it is used, and whether its performance remains acceptable as clinical practice changes. A new Review in @CellCellPress, "Avoiding common failures in AI for health and medicine," examines reliability across both predictive and generative AI. The authors highlight three recurring and often interconnected failures. 1๏ธโƒฃ ๐—˜๐—ฟ๐—ฟ๐—ผ๐—ป๐—ฒ๐—ผ๐˜‚๐˜€ ๐—ผ๐˜‚๐˜๐—ฝ๐˜‚๐˜๐˜€ ๐—บ๐—ฎ๐˜† ๐—ฏ๐—ฒ ๐—ฑ๐—ถ๐—ณ๐—ณ๐—ถ๐—ฐ๐˜‚๐—น๐˜ ๐˜๐—ผ ๐—ฑ๐—ฒ๐˜๐—ฒ๐—ฐ๐˜ Predictive models can learn from incomplete records, inconsistent labels, or proxies that do not accurately represent the underlying clinical condition. Generative AI can produce fluent and authoritative responses that are clinically incorrect, making unreliable outputs particularly difficult to recognize. 2๏ธโƒฃ ๐—”๐˜ƒ๐—ฒ๐—ฟ๐—ฎ๐—ด๐—ฒ ๐—ฝ๐—ฒ๐—ฟ๐—ณ๐—ผ๐—ฟ๐—บ๐—ฎ๐—ป๐—ฐ๐—ฒ ๐—ฐ๐—ฎ๐—ป ๐—ฐ๐—ผ๐—ป๐—ฐ๐—ฒ๐—ฎ๐—น ๐˜‚๐—ป๐—ฒ๐—พ๐˜‚๐—ฎ๐—น ๐—ฝ๐—ฒ๐—ฟ๐—ณ๐—ผ๐—ฟ๐—บ๐—ฎ๐—ป๐—ฐ๐—ฒ A system may perform differently across patient populations, hospitals, scanners, input formats, or clinical settings for reasons unrelated to genuine clinical differences. Strong overall results may therefore coexist with clinically important failures for particular populations or contexts. 3๏ธโƒฃ ๐—ฃ๐—ฒ๐—ฟ๐—ณ๐—ผ๐—ฟ๐—บ๐—ฎ๐—ป๐—ฐ๐—ฒ ๐—ฐ๐—ฎ๐—ป ๐—ฑ๐—ฒ๐—ด๐—ฟ๐—ฎ๐—ฑ๐—ฒ ๐—ฎ๐—ณ๐˜๐—ฒ๐—ฟ ๐—ฑ๐—ฒ๐—ฝ๐—น๐—ผ๐˜†๐—บ๐—ฒ๐—ป๐˜ Changes in patient populations, workflows, documentation practices, coding systems, or data collection can make a previously validated model less reliable. These changes may be gradual, difficult to observe, and entangled with the model's own effects on clinical decisions and recorded outcomes. The paper also explains why familiar technical fixes are often insufficient. Data cleaning, model refinement, retrieval systems, recalibration, and retraining can help, but they frequently depend on assumptions that don't hold in dynamic clinical environments. Addressing one known failure may also leave other failures undetected or introduce new ones. The authors therefore frame reliability as a lifecycle responsibility. Reliable healthcare AI is not achieved by optimizing a model once. It requires continuous coordination across technical evaluation, clinical oversight, monitoring, and institutional governance. Olawale Salaudeen, et al. Avoiding common failures in AI for health and medicine. Cell. 2026; 189: 5893-5904. doi.org/10.1016/j.cell.2026.โ€ฆ #AIGovernance #HealthAI #ResponsibleAI #TrustworthyAI #ClinicalAI #AISafety #GenerativeAI #DigitalHealth #HealthcareInnovation #DukeNUS [๐—”๐—œ ๐—š๐—ผ๐˜ƒ๐—ฒ๐—ฟ๐—ป๐—ฎ๐—ป๐—ฐ๐—ฒ & ๐—ฃ๐—ผ๐—น๐—ถ๐—ฐ๐˜† ๐—–๐—ผ๐—ฟ๐—ป๐—ฒ๐—ฟ] is a regular series in which we will share and reflect on relevant research, frameworks, and policy developments shaping trustworthy and ethical AI in healthcare.
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In a The New York Times @nytimes op-ed, geriatrician Dr. Rachael Bedard shares a striking confession: #AI is making her a better doctor, but she worries it's making her trainees worse. As Dr. Adam Rodman, physician and AI researcher at Harvard Medical School, put it in the piece: "the cognitive offloading can cause never-skilling." The New York Times article: lnkd.in/g_K7wQKc Glad to see our research aligning with what's being observed at a major international venue. Read more about this concept in our @NatureMedicine article "AI-induced never-skilling in medical education" (nature.com/articles/s41591-0โ€ฆ). #NeverSkilling #AIinMedicine #AI #MedicalEducation #ClinicalReasoning #DukeNUS
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๐Ÿ“ขNew in @NatureHumBehav: "How AI companions could deepen social inequality," with @qiyang_zhang & @renwenzhang. AI companions feel more patient & available than any human relationship - so who really benefits? nature.com/articles/s41562-0โ€ฆ #AI #inequality #SMU #NTU #DukeNUS
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Retrieval-Augmented Generation (#RAG) in medicine: promising, but still early-stage. #LLMs are transforming clinical practice, but hallucinations, static knowledge, and bias remain real risks. Our @CellRepMed paper shows where the field stands. cell.com/cell-reports-mediciโ€ฆ #DukeNUS
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Attending International Conference on Machine Learning (#ICML) at Seoul. Happy to connect and talk about #AI and #ML for #healthcare and #medicine.
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Skin cancer #AI models can exhibit #gender #bias. Our work introduces #LesionAttn, which focuses on clinician-annotated lesions while down-weighting background signals. @npjDigitalMed @NaturePortfolio nature.com/articles/s41746-0โ€ฆ #Dermatology #AIFairness #MedicalAI #DigitalHealth
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Nan Liu, Duke-NUS retweeted
We've written about AI-induced physician deskilling that has already surfaced thelancet.com/journals/lanceโ€ฆ @tberzin AI-induced never-skilling among newly trained doctors, while not yet proven, is a serious concern that needs to be addressed @NatureMedicine @nliulab nature.com/articles/s41591-0โ€ฆ
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Our new @NatureMedicine Perspective argues that uncritical use of #AI in early medical training may weaken independent clinical reasoning, and proposes a framework for integrating AI while protecting core competencies. nature.com/articles/s41591-0โ€ฆ @NaturePortfolio @dukenus #DukeNUS
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๐—–๐—ฎ๐—ป ๐—”๐—œ ๐—ฐ๐—ผ๐—บ๐—ฝ๐—ฎ๐—ป๐—ถ๐—ผ๐—ป๐˜€ ๐—ฟ๐—ฒ๐—ฎ๐—น๐—น๐˜† ๐—ฟ๐—ฒ๐—ฝ๐—น๐—ฎ๐—ฐ๐—ฒ ๐—ต๐˜‚๐—บ๐—ฎ๐—ป ๐—ฟ๐—ฒ๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐˜€๐—ต๐—ถ๐—ฝ๐˜€? We argue that #AI companionship is not just a technical innovation but a deepย relational shift. papers.ssrn.com/sol3/papers.โ€ฆ #AICompanions #GenAI #DigitalIntimacy #AIethics #DukeNUS
Made with AI
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Ambient AI is no longer just documenting care. Itโ€™s starting to shape it. In our latest in @npjDigitalMed article, we examine how ambient AI scribes are moving into complex care settings, and why that changes everything. nature.com/articles/s41746-0โ€ฆ
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๐Ÿ“œInnovating global regulatory frameworks for generative AI in medical devices is an urgent priority. @NaturePortfolio @npjDigitalMed Read paper: doi.org/10.1038/s41746-026-0โ€ฆ #GenerativeAI #LLM #AIinHealthcare #DigitalHealth #MedTech #HealthAI #AIRegulation #ResponsibleAI #DukeNUS
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By analyzing 19,123 #NLP-related studies using topic modeling, we mapped the research landscape on #LLMs vs non-LLMs, and compared task distributions and application contexts across these two technical paradigms. @NaturePortfolio npj Health Systems nature.com/articles/s44401-0โ€ฆ
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