This influence extends to contemporary digital art and NFTs, exemplified by the @OpenSea "Profile Pictures" collection, launched in November 2025 by Ito and Xanthrax, which explicitly draws from Bacon's papal studies by incorporating distorted papal imagery, such as a pope in an electric chair, as a modern extension of the screaming pope motif within cryptocurrency culture

No, it definitely won't. I personally spent several years building SHA-256 as a Boolean circuit and then using all the most sophisticated techniques known to math and cryptography to try to invert that function (to execute a preimage attack). I know the math of SHA-256 more deeply than most people on this planet. It's exceptionally well-defined as a trapdoor function, and inverting it is most certainly NP complete. I also spent over 30 years trying to prove that P = NP, and threw my entire 30 years of knowledge of this problem at frontier LLMs to try to crack it. What they ended up doing was to thoroughly and convincingly refute every single line of reasoning and "clever" trick I came up with over those decades, which has now left me believing for the first time that actually P≠NP.

there are lots of crazy good experiments still happening onchain and I try to repost them whenever I can

love details on a site like this

just bid on all of these 48 hours come outbid me

Everything you need to know about

In 1994 I had a college internship at Berkshire Hathaway and the 2nd Friday of each month the interns would dine with Warren Buffet and he would share wisdom with us such as: “Never underestimate how dumb your opponent is in business. If they do a lot of things that are incredibly stupid, keep in mind they actually spent time coming up with those things. If you present to them a challenge in real time you will learn how stupid they actually are. Use this to your advantage”. And then on the last lunch he pulled me aside as everyone was leaving and looked me in the eye and said: “Doug. One day in your future you will be at odds with a Mossad backed company. This is very important to remember. Make fun of their company name publicly. They will lose their shit and make terrible decisions and show the world what they really are.” I nodded pretending that wasn’t the dumbest shit I’ve ever heard and shook his hand and thanked him for the internship. He really is the Oracle of Omaha.

me pulling up alongside @Muse @bot @r_alx_z

more community

I am giving away 1 MUSEGOD NFT To one lucky person! Quote repost this & the space. Tag two friends. Drop your wallet. Pick your muse.

Sam Altman's one-person company prediction is coming true. Anthropic just bought one. The founder of Mithril Medicine used Claude to take a muscular dystrophy antibody treatment from concept to proof-of-principle in mice in 18 months, with just himself, Claude, and part-time consultants. The technical report is great. I will quote: 'The week opened with the handover of two cell-based assays, cell adhesion and flow cytometry, within our team, while eleven questions remained open with the assay CRO. In two sentences, one of us asked Claude to review the latest emails between the outgoing assay lead and the assay CRO and to recommend next steps for the handover, and gave it the link to the handover folder. Claude returned a bottom line after 96s and a full plan with five drafted emails after 18 min. For the full plan it read six email threads, the handover folder, two slide decks and two reports, all in the mailbox and file store to which we had given it access. Four working days later, nine of the eleven questions had an answer in writing and the other two had been left to pilot experiments. The adhesion screen was thereby set out in writing. The CRO drew the plate map to the format that our team had requested, Claude compiled the run order and the material calculation from the production data, and one of us reviewed and approved them. On day 4, the production CRO delivered its data package, a report of 341 pages, which one of us forwarded to Claude in two sentences, with the request to review it, share observations and recommend next steps. Claude returned a bottom line after 2 min 40s and, once it had read every page, a visual synthesis of all 113 constructs after 7 min 53s. The synthesis arranged the constructs on the grid of 14 by 8 arms. Claude marked 82 constructs for screening as is, seven for additional polishing, and the 24 constructs of three laminin-binding arms to be held back from the cell-based assays on production criteria. Each of the 113 constructs thus had a proposed next step in less than 8 min. Claude had recommended binding kinetics for all 113 con-structs, and on day 7 one of us challenged this plan. Claude defended it within 27s, arguing that affinity would show whether the three arms merit further work. One of us overruled this recommendation and set the three arms aside on production criteria. Their material remains in storage. Four minutes later, Claude had revised its memo, the working page, the run order and three unsent drafts from 113 to 89 constructs. It had also applied the ruling to three dependent steps in the unsent drafts, each flagged for our veto. The exchange took 7 min 36s from challenge to new plan, and every affected email was still an unsent draft. After the ruling, eight emails drafted by Claude went out on the same day to three CROs and a consultant. Over the whole week, Claude drafted 17 emails, each in answer to a request from one of us, and we sent 12 of them, each after editing. With its drafts, Claude listed 41 points, such as tube fills, shipping conditions, recipients and assay settings, for which it had found no written statement of ours, so that we could confirm, change or strike each before sending. We kept some, struck others and changed one. Among the passages that we kept were proposals for controls. One draft proposed a comparison of polished and unpolished material on one sensor chip, to size the error that impurities cause in the rest of the panel. Another requested a buffer control diluted like the most dilute sample, so that any effect of the buffer appears at its largest. These proposals concerned the measurement of constructs that had already been produced, and each reached a CRO only after one of us had reviewed and approved it.

From 2011 - 2014, the Thiel Fellowship gave out 40 $100k fellowships to entrepreneurs That were all under 20 years old at the time... 13 unicorns have since been built by those 40 fellows 4 of those 40 fellows are also now billionaires Absolutely insane hit rate

notifications @nicedayJules

the biggest problem with @muse is there is no trust between my various muse agents, but with @grok each of my @bot have implicit trust between them. I can coordinate between them easily but I can't with muse

paint the world

Stripe's landing page has the biggest flex ever

We needed better onchain standards for marketplaces at @opensea, so we’re proposing one. ERC-8451 adds permanent locks to lockable tokens, so collections can identify if they are soulbound. Feedback welcome on the PR.

"the whole AI revolution blindsided me" from one of the best fiction writers I've ever come across

Oh, is that @nealstephenson coming on the Core Memory podcast tomorrow? Why, yes, it is. There's quite the irony in him saying, "the whole AI revolution blindsided me."

reading the replies to this makes it clear who doesn't understand why this is such a great ad by notion