Robert Lufkin MD
@robertlufkinmd

Professor & NYT bestselling author of Lies I Taught in Medical School. Metabolic health, longevity & what your doctor gets wrong. Free weekly newsletter 👇

 California
robertlufkinmd.substack.com
Joined July 2019
11,014 Photos and videos
Article

Walking Won’t Burn Fat — Here’s What It Actually Does

Your body compensates for 80% of exercise calories. Walking doesn’t work because it burns fat. It works because it changes the hormonal environment that controls fat storage. Walking videos are

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Lower-carb was not the only route to a lower LDL reading in this trial (study: doi.org/10.1038/s41598-026-7…). (1/5)
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Provisional GRADE-informed (4-week LDL): Low - analysis choices and imprecision (methods: doi.org/10.1038/s41598-026-7…). My takeaway: evaluate the whole meal pattern, not just its carb label. (4/5)

Optimized Nutri-Dense meals versus a low-carbohydrate high-fat diet: an exploratory randomized...

Scientific Reports - Optimized Nutri-Dense meals versus a low-carbohydrate high-fat diet: an exploratory randomized controlled trial

nature.com
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Full breakdown coming on the Health Longevity Secrets podcast piped.video/@RobertLufkinMD #MetabolicHealth #HealthLongevitySecrets #Nutrition #Cholesterol (5/5)

RobertLufkinMD

NYT bestselling author | Medical school professor | Health & Longevity I spent 30 years as a medical school professor teaching future doctors. Then I realized we were treating symptoms—not causes....

youtube.com
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When insomnia and sleep apnea overlap, is sleep-hygiene advice enough? (1/5)
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Provisional GRADE-informed (3-month insomnia severity): Moderate - unblinded self-reported outcomes (methods: doi.org/10.1093/ajrccm/aamag…). My takeaway: a structured, clinician-guided program is not the same as a list of sleep tips. (4/5)

Clinician-guided digital CBT-I improves sleep quality and apnea severity in patients with co-morbid...

AbstractRationale. Cognitive behavioral therapy for insomnia (CBT-I) is the accepted first-line treatment for insomnia, but its scalability and safety in p

academic.oup.com
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Full breakdown coming on the Health Longevity Secrets podcast piped.video/@RobertLufkinMD #MetabolicHealth #HealthLongevitySecrets #Sleep #Insomnia (5/5)

RobertLufkinMD

NYT bestselling author | Medical school professor | Health & Longevity I spent 30 years as a medical school professor teaching future doctors. Then I realized we were treating symptoms—not causes....

youtube.com
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A 14 to 16 hour overnight fast a few times a week turns up mitophagy. Cold exposure makes brown fat mitochondria burn fat for heat. Sauna triggers heat shock proteins that protect mitochondrial membranes. Full episode: piped.video/61PbwUZtvt8
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1,000 samples. Just 20 people (study: doi.org/10.1186/s12916-026-0…). (1/5)
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Provisional GRADE-informed (acute protein responses): Very low - small sample and meal-order bias concerns (methods: doi.org/10.1186/s12916-026-0…). My takeaway: a molecular map is a research lead, not a verdict on your diet. (4/5)

Proteomic profiling of acute postprandial responses to five single-meal challenges and implications...

BMC Medicine - Diet influences human health, but the acute molecular effects of individual meals remain incompletely understood. In this prospective crossover study, 20 healthy volunteers underwent...

link.springer.com
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Full breakdown coming on the Health Longevity Secrets podcast piped.video/@RobertLufkinMD #MetabolicHealth #HealthLongevitySecrets #Nutrition #Proteomics (5/5)

RobertLufkinMD

NYT bestselling author | Medical school professor | Health & Longevity I spent 30 years as a medical school professor teaching future doctors. Then I realized we were treating symptoms—not causes....

youtube.com
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A diet's value is not just a number on the scale. (1/5)
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Provisional GRADE-informed (8-week HOMA-IR): Low - bias concerns and uncertain effect size (methods/results: doi.org/10.3390/nu18213519). My takeaway: separate a promising metabolic signal from a reason to buy a DNA test. (4/5)

Effects of a Nutrigenetic Diet on Fat Mass Loss, Insulin Resistance, and Subclinical Inflammation...

Background: Abdominal obesity (AO) is involved in the development of cardiometabolic disorders, in which factors such as diet and genetics play crucial roles. In this context, interactions between...

mdpi.com
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Full breakdown coming on the Health Longevity Secrets podcast piped.video/@RobertLufkinMD #MetabolicHealth #HealthLongevitySecrets #Nutrition #InsulinResistance (5/5)

RobertLufkinMD

NYT bestselling author | Medical school professor | Health & Longevity I spent 30 years as a medical school professor teaching future doctors. Then I realized we were treating symptoms—not causes....

youtube.com
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