Assistant Professor of Molecular and Cell Biology and Chemistry at UC Berkeley @berkeleyMCB @UCB_Chemistry
Berkeley, CA
- Tweets 248
- Following 663
- Followers 913
- Likes 4,819
Robert Saxton retweeted
A third preprint dropped by the Garcia Lab this week, another project led by Pingdong Tao: "All-by-All Cytokine Receptor Pairing Network Unlocks Coding of Non-Natural T Cell States" biorxiv.org/content/10.64898…
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Robert Saxton retweeted
MCB is hiring Assistant Professors across 3 divisions!:
🧪 BBS: aprecruit.berkeley.edu/JPF05…
🧬GGED: aprecruit.berkeley.edu/JPF05…
🦠IMM: aprecruit.berkeley.edu/JPF05…
🗓️ Application Deadline: October 19, 2026
🔗 Click the links or scan the QR codes to learn more and apply
ALT MCB is hiring 3 Assistant Professor positions across 3 divisions: Biochemistry, Biophysics and Structural Biology (BBS); Genetics, Genomics, Evolution, and Development (GGED); and Immunology and Molecular Medicine (IMM) BBS application link: https://aprecruit.berkeley.edu/JPF05483 GGED application link: https://aprecruit.berkeley.edu/JPF05481 IMM application link: https://aprecruit.berkeley.edu/JPF05486
ALT Assistant Professor of Immunology and Molecular Medicine. IMM application link: https://aprecruit.berkeley.edu/JPF05486
ALT Assistant Professor of Biochemistry, Biophysics and Structural Biology (BBS). BBS application link: https://aprecruit.berkeley.edu/JPF05483
ALT Assistant Professor of Genetics, Genomics, Evolution, and Development (GGED). GGED application link: https://aprecruit.berkeley.edu/JPF05481
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Congratulations @CalebGlassman!! Impressive discovery + mechanistic characterization of many new ways viruses hijack their hosts ubiquitin-proteasome system 🤩
We have a new paper online today at @ScienceMagazine! We applied our recently developed library of viral open reading frames to discover and characterize viral ubiquitin ligases. science.org/doi/10.1126/scie…
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Robert Saxton retweeted
How specific are therapeutic monoclonal antibodies, really?
In our new paper, @Yile_Dai led a collaboration with Adimab to profile 174 FDA-approved and clinical-stage mAbs against 6,172 human extracellular proteins.
What we found surprised us.🧵
sciencedirect.com/science/ar…
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Excited to share our new @Nature paper! We developed an IL-2–TGFβ co-agonist that enables efficient induction of antigen-specific pTregs and establishment of immune tolerance in vivo. An important step toward programmable immune tolerance. rdcu.be/e72lN
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Robert Saxton retweeted
Excited to share our new study using engineered immune proteins to quench inflammation in aged brains!!
Congratulations to @Paloma_Negredo and team!
Fantastic collaboration with several labs - Chris Garcia's lab, @rsaxton_, @theRafLab, @wysscoray, and @VilledaLab!
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Robert Saxton retweeted
Thrilled to share the primary focus of my PhD thesis work, now out in @ScienceMagazine today!
We developed Trikines — engineered cytokines that reconfigure receptor complex assembly to reshape signaling directly in endogenous immune cells.
doi.org/10.1126/science.adx9…
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Robert Saxton retweeted
My mentor Chris Garcia just put out an absolute banger. Required reading for protein design/engineering.
Why are natural protein-protein interfaces easier to target with new binders/mAbs than "silent" surfaces? It's not training bias... it's biophysics.
science.org/doi/10.1126/scie…
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Very exciting new preprint from Chris Garcia’s lab: development of an engineered TGFb agonist (derived from helminths!) that drives cell-type selective immune suppression. 🔥biorxiv.org/content/10.64898…
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Robert Saxton retweeted
We're Hiring! Assistant Professor of Immunology and Molecular Medicine in MCB. Learn more and apply online:
aprecruit.berkeley.edu/JPF05…
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Robert Saxton retweeted
We're Hiring! Assistant Professor of Molecular Therapeutics in MCB. Learn more and apply online: aprecruit.berkeley.edu/JPF05…
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Robert Saxton retweeted
An incredible follow up to the Garcia Lab ortho-IL-2 receptor system published in @Nature today led by @YangZhao102. It's been an honor learning from Yang and co-authors in the process of bringing this project to fruition. A tour de force- check it out! rdcu.be/eACzg
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Robert Saxton retweeted
Excited to announce a new collaboration between the Molecular Therapeutics Initiative (MTI) and Amgen Inc.! This partnership includes funding for cutting-edge research & an internship program for grad students to train in drug discovery & development at Amgen. #MTI #Amgen #Biotech #UCB
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Robert Saxton retweeted
Excited to share this work from the Garcia Lab out today in @NatureComms! We engineer "cytokine adaptors", molecular switches that simultaneously block a target cytokine while inducing local activation of alternative cytokine receptors. rdcu.be/ec7GS
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Robert Saxton retweeted
More than 2/3 of new medicines are created by biotech and in-licensed by pharma, and nearly every innovative biotech comes from academia. That’s because it takes years and years of sustained and consistent focus and perseverance on a basic biological problem to lead to innovative drugs. This is not something that pharma can usually support. Youtube Jim Allison and checkpoint blockade.
Yes, we can improve efficiency, but IMHO the NIH should come up with creative solutions to expand the pipeline and participate in the upside of medicines that it helps create, rather than severely cutting infrastructure for a key industry and opportunity for US growth.
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Robert Saxton retweeted
Scientific Director, Cal-Cryo. We're looking for an outstanding microscopist to run our cryo-EM facility (two Krioses and an Arctica). Apply now to join our outstanding community of cutting edge cryo-EM/ET researchers! tinyurl.com/ykasna3p
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Exciting new work from @karstenhouse_14 and the Garcia Lab, congrats!!
Proud to share early work from my 1st year in the Garcia Lab! 🧬 the tldr: in just a few months, we go from computational design —> real cancer-specific T cell engagers!
biorxiv.org/content/10.1101/…
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Robert Saxton retweeted
Grateful to @berkeleyMCB for highlighting our lab and our recent discoveries! It was fun to discuss some of the surprises during our research on lipid homeostasis, lipid droplets, & ferroptosis—driven by exceptional UC Berkeley students & postdocs. mcb.berkeley.edu/news-and-ev…
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Robert Saxton retweeted
New website for our amazing Molecular Therapeutics Initiative @MTI_UCB . Please check it out and get involved!
moleculartherapeutics.org
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Robert Saxton retweeted
We're Hiring! Assistant Professor of Immunology and Molecular Medicine in MCB. Learn more and apply online: aprecruit.berkeley.edu/JPF04…
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