Interviews in local language (translated with AI to English) of cat parents - European elderly cats with sarcopenia (age-related muscle loss), improving on our therapeutic. I thought I should keep this for strategics and investors, but the same reactions I see in their pharma teams is what the world at large should experience too. We're working on improving health, on going beyond just nine lives ❤️

Dr. @mkaeberlein has just joined @thecathealthco's Scientific Advisory Board. @AlexBacita, myself and the team at TCHC have been looking up to Dr. Kaeberlein's work for a long time. As a founder of The Dog Aging Project, founding Director of the Healthy Aging and Longevity Research Institute at The University of Washington, author of hundreds of scientific articles with more than 30,000 citations by other scientists, and leader involved in multiple successful biotech companies, Dr. Kaeberlein brings deep expertise to our company and we are delighted to leverage this for our next feline projects. More details in the thread!

Our first pharma licensing deal signed ✅ for PURR-001 (feline sarcopenia therapeutic) at @thecathealthco Expect to hear more about the broader group of companies that will help us to approve and distribute this once-weekly capsule for all who need it. Our cats deserve more tomorrows, better quality of life 😺

Screw it, we're giving a free blood test to every American. Today we're launching Death Clock. No one lives forever. The only question is: when? We trained an AI to predict your date, then move it. One app. Years added to your life. Real needle, real lab, $0.

How could tiny breakthroughs in aging science change U.S. GDP and population growth? What’s the economic value of making 41 the new 40, or 65 the new 60? How many lives could we create or save if we could slow reproductive or brain aging by just 1 year? What would billions of healthier hours be worth to the economy, if we assume no change in the age of retirement? I spent the last two years obsessing over the design, research, and execution of this project. The result is a book upcoming with Harvard University Press, a preprint, and—maybe your favorite part—an interactive simulation tool that lets you input your own timelines and assumptions for specific breakthroughs in aging bio, then see the ROI in terms of US population & GDP growth. From @RickEcon and Jason DeBacker—the economists who co-developed the open-source, macro model that made this project possible—to extensive comments by @tylercowen, @sapinker, Richard Freeman, @NDHendrix, @ebudish, @elidourado, @geochurch, @jasoncrawford as well as interviews with 102 scientists (!) and countless iterations with award-winning designer Giorgia Lupi and the @pentagram team, we built something we hope will be a benchmark for how scientists, economists, designers, philosophers, entrepreneurs and storytellers can come together to paint, fund, and build different flourishing futures for our species. I couldn’t be more excited to share this. It’s the start of an open and evolving project—the labor and product of love, obsession, and unrelenting care. I hope you have fun playing with our simulation tool — and if you do, please share!

Gameto, an Austin, TX-based clinical-stage biotechnology company developing stem cell-derived therapies for reproductive health, raised $44M in Series C funding finsmes.com/2025/08/gameto-r…

Want to help push aging biology research forward? 🚀 You can make an impact today: 📝 Speak up — Contact your local representatives and state senators. Email us at info@a4li.org for tips on what to say. 💬 Share your story — Tell us why this research matters to you: forms.gle/pAHkG1UYGyuD8Smm7. Small actions today can lead to big breakthroughs tomorrow.

The time is now for thoughtful longevity policy. Please read this op-ed: @theA4LI theepochtimes.com/opinion/pr…

Super excited about @foresightinst and their new Bio & Nano Grants -- fast turnaround of small grants to help frontier longevity biotechnology or molecular nanotechnology ideas and projects get off the ground. If that’s you, I encourage you to apply here: foresight.org/bio-nano-grant…

Over-exercising induces irreversible liver fibrosis (who knew?) by inducing the secretion of damaging vesicles from muscles called “lactate bodies” @Cell_Metabolism

Congrats to the Gameto team on FDA clearance for the Phase 3 trial of a technology that makes IVF easier on women! businesswire.com/news/home/2…

(1/) I am thrilled to announce that @GametoGen has received FDA clearance to launch our Phase 3 clinical trial for Fertilo - the first iPSC-based therapy to enter this stage since Shinya Yamanaka’s Nobel Prize-winning discovery of iPSCs. businesswire.com/news/home/2…

I’d like to introduce you to Death Clock—an AI-powered longevity app that I’ve been advising for the last 6 months. Health apps are notoriously difficult to grow: they are single-player utilities that resonate most with older audiences. However, I worked with the founder @brentfranson and we did some simple things that made the experience social and drove the cost of acquisition down to pennies...

🌟 Exciting News for the Future of Health and Longevity! 🌟 We’re thrilled to officially announce the launch of LongeviPAC — the first political action committee dedicated to advancing pro-longevity policies in the United States! 🚀 🔗 longevipac.org/ 🧵1/8

In March 2024, we hosted our inaugural D.C. Fly-In, bringing together industry leaders, academics, investors, and policymakers. Despite the challenges of navigating a potential government shutdown, we successfully showcased the importance of representing the longevity science industry on Capitol Hill. This achievement was made possible by our incredible A4LI sponsors and community, who recognized the critical role of this field. We were honored to introduce our Longevity Science Caucus on Capitol Hill for the first time, with Co-Chairs Congressmen Paul Tonko and Gus Bilirakis delivering impactful opening remarks at the Longevity Science Briefing. Join us in shaping the future of healthier, longer lives at our 2025 D.C. Summit, happening April 28th–30th. With a newly appointed Health Cabinet supportive of longevity science and a renewed national push to make the United States a global leader in scientific innovation, 2025 offers a unique window of opportunity. Don’t miss your chance to be part of this transformative moment—learn more at a4li.org/dc-summit-2025/!

Gameto Announces World’s First Live Birth Using Fertilo Procedure that Matures Eggs Outside the Body - businesswire.com/news/home/2…

The success of AI applied to drug discovery is being decided by a number of clinical trials. So far, the results are lackluster. Why? For AI to have a transformational effect in drug discovery, training data must come from living mammals. (🧵1/9)

FDA approves new blood test to screen for colon cancer nbcnews.com/health/health-ne… via @nbcnews

Shouldn’t aging be part of drug discovery for diseases of aging? gordian.bio/blog/introducing… Gordian exists to move therapeutic testing from plastic wells and young mice into a living environment with all the complexity present in patients with age-related disease. We’re now sharing results showing how pooled in vivo screening can make highly accurate physiological predictions and find novel treatments for diseases of aging 🧵1/15