Our main focus is to offer innovative tools for live cell fluorescence imaging to the scientific community.
Switzerland
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You can't image what you can't see. Spirochrome makes it visible.
📄 4,000+ published articles 🌍 Hundreds of research groups worldwide 📰 High-impact journals
Fluorescent probes that push the boundaries of live-cell imaging.
→ spirochrome.com/
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Spirochrome retweeted
You can't image what you can't see. Spirochrome makes it visible.
📄 4,000+ published articles 🌍 Hundreds of research groups worldwide 📰 High-impact journals
Fluorescent probes that push the boundaries of live-cell imaging.
→ spirochrome.com/
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Spirochrome retweeted
Spirochrome is on Bluesky! Don't forget to give us a follow when you make it there, we'll follow you back!
🦋🦋🦋
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Spirochrome probes: the Standard for live-cell imaging.
📊 1700+ publications cite SiR-actin, 📊 1300+ cite SiR-tubulin, 📊 1200+ cite SiR-DNA
Trusted by thousands of labs worldwide.
Join the community → spirochrome.com/products/?_c…
#LiveCellImaging #Microscopy #Fluorescence
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Spirochrome retweeted
And it's not all: For an exceptional new product, an exceptional new casing!
We designed new boxes that we will gradually deploy to replace our old metal boxes. 4 designs will be randomly used for each product!
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Today is the Day, CenSpark650 is available!
Time to get those centrioles and cilia shining under the 🔬objective!
spirochrome.com/product/cens…
video: 20h imaging of primary cilium formation in a single RPE-1 cell stained with CenSpark650.
movie credits: Cédric Pourroy
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📢On June 1st, we will be launching CenSpark650, the very first selective fluorescent probe for imaging centrioles and cilia in live cells.🔬
No transfection, zero genetic manipulation. Just Add & Image 1 hour later.
Learn more: spirochrome.com/12-may-2026/ #Bioimaging
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We strongly recommend reading the article by Cedric Pourroy et al. to get to know everything CenSpark650 can do and beyond:
nature.com/articles/s41589-0…
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Spirochrome retweeted
Overly proud that Katie Holden's image won Evident Microscopy's 6th Annual Image of the Year "Global Winner" award🏆
The image shows live iPSC-derived neurospheres. DNA (magenta) & MT (blue) were stained with our probes SiR-tubulin & SPY555-DNA probes
evidentscientific.com/en/lan…
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Overly proud that Katie Holden's image won Evident Microscopy's 6th Annual Image of the Year "Global Winner" award🏆
The image shows live iPSC-derived neurospheres. DNA (magenta) & MT (blue) were stained with our probes SiR-tubulin & SPY555-DNA probes
evidentscientific.com/en/lan…
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If you want to know more about IPSC-derived neurospheres, we strongly advise to read Katie Holden's research article which introduces this technology: doi.org/10.1016/j.bbi.2023.1…
Congrats Katie!
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Spirochrome retweeted
Mesmerizing light sheet imaging of neutrophils swarming at a yeast target!
The neutrophils were labeled with SPY650-DNA (yellow) and a calcium dye (blue).
This movie is part of the recent manuscript by
Evelyn Strickland that we highly recommend reading! biorxiv.org/content/10.64898…
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Spirochrome retweeted
CenSpark is a dual-ligand fluorescent probe simultaneously binding inner and outer microtubule sites – a configuration unique to doublet and triplet microtubules, enabling selective live imaging of centrioles and cilia across species
nature.com/articles/s41589-0…
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Spirochrome retweeted
Beware the SPY488-FastAct rollercoaster!
We teamed up with @CSRBiotech and their incredible MI-SIM microscope to drive you through the intricate actin network of live COS7 cells stained with SPY488-FastAct.
Find out more about SPY488-FastAct: spirochrome.com/product/spy4…
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Beware the SPY488-FastAct rollercoaster!
We teamed up with @CSRBiotech and their incredible MI-SIM microscope to drive you through the intricate actin network of live COS7 cells stained with SPY488-FastAct.
Find out more about SPY488-FastAct: spirochrome.com/product/spy4…
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🙏 @christlet for the cool "Animated Zooming" & "Animated panning" ImageJ plugins used here! 😎
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