Sipei Fu retweeted
Glad to share a new story on how Lac-Phe enters the bloodstream from the gut: a monocarboxylate transporter MCT6 does the job! Interestingly, within the same SLC16 family, MCT1 transports lactate, and MCT10 transports Phe. Thanks to all collaborators who made this work possible!
Lac-Phe is an exercise💪 and metformin💊 inducible blood-borne metabolite that suppresses appetite. How does Lac-Phe get into circulation? New from @Shuke_Xiao: a transporter deorphanization story that links local cellular metabolism to systemic activity:
biorxiv.org/content/10.64898…
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Cool and fun 🐍science! Thank you the Leinwand lab for hosting us!
A big thank you to Leslie Leinwand lab for hosting @Shuke_Xiao @ssiipei this week @CUBoulder. Learning more about 🐍 husbandry to get our own colony up and going @Stanford_ChEMH
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Sipei Fu retweeted
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