Aaron Douglas@Akaron0884

Postdoctoral fellow investigating neuroimmune interactions for brain-body communication.

 Dublin City, Ireland
Joined May 2017
21 Photos and videos
Very excited to share part of my postdoctoral work from the @RyanLabTCD, out now in @Nature. Here, my brilliant co-author @Andrea_MZamora and I explored the link between memory engrams and whole-body metabolism. A thread: 🧵 nature.com/articles/s41586-0…

Cold memories control whole-body thermoregulatory responses

Nature - Cold-sensitive engrams contribute to learned thermoregulation in mice that are returned to an environment in which they previously experienced a cold challenge, through a network formed...

nature.com
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Thrilled to share this news and to be able to continue brain-body research at the Enamorado Lab!
Michel Enamorado@Michel_Enamorad
13 Dec 2025
🎉 The Enamorado Lab is closing out 2025 with big news! @Andrea_MZamora, PhD awarded the 2025 @CancerResearch Irvington Postdoctoral Fellowship to study immune engrams. #ProudPI @IcahnMountSinai @SinaiBrain @MSHSDerm @SinaiImmunol cancerresearch.org/cri-funde…
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Aaron Douglas retweeted
Ryan Lab@RyanLabTCD
12 Nov 2025
Sickness engrams modulate anticipatory immune responses biorxiv.org/content/10.1101/…

Sickness engrams modulate anticipatory immune responses

A threat to survival in the wild is vulnerability to infection. The immune system is essential for defence against foreign species which cause sickness. During infection the brain triggers conserved...

biorxiv.org
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Aaron Douglas retweeted
Nature Metabolism
@NatMetabolism
25 Jul 2025
The source of dietary fat influences anti-tumour immunity in obese mice go.nature.com/4o2w4CJ
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Very excited to share part of my postdoctoral work from the @RyanLabTCD, out now in @Nature. Here, my brilliant co-author @Andrea_MZamora and I explored the link between memory engrams and whole-body metabolism. A thread: 🧵 nature.com/articles/s41586-0…

Cold memories control whole-body thermoregulatory responses

Nature - Cold-sensitive engrams contribute to learned thermoregulation in mice that are returned to an environment in which they previously experienced a cold challenge, through a network formed...

nature.com
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This work was supported with funding from @IrishResearch, @Researchirel, @ERC_Research and @NIH, and was carried out across multiple institutions including @tcdTBSI, @tcddublin, @BrighamWomens, @Harvard, @PrincetonMolBio, @Princeton and @Columbia.
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@Andrea_MZamora and I are now based in the Icahn school of Medicine at Mount Sinai in the brilliant labs of @Michel_Enamorad and @cam_phd respectively, so keep an eye out for the cool work to come from there also!
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Aaron Douglas retweeted
Cameron McAlpine@cam_phd
17 Apr 2025
We are thrilled to share the latest from the lab! We demonstrate that multi-organ MCSF-dependent myelopoiesis is dynamic in MS and is manipulated by lifestyle to influence disease severity and neuroinflammation. Big congrats to the whole team! nature.com/articles/s41467-0…

Myelopoiesis is temporally dynamic and is regulated by lifestyle to modify multiple sclerosis

Nature Communications - Myeloid cells contribute to the etiology of multiple sclerosis (MS), but the dynamics of myelopoiesis during disease progression is still unclear. Here the authors show, in...

nature.com
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Thank you to @NatureRevEndo for their perspective piece on our recent paper from the @lynchielydia lab! Online @Nature
Nature Reviews Endocrinology@NatureRevEndo
8 Nov 2024
New content online: IL-17 has a role in whole-body homeostasis go.nature.com/3NY2Rb1
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A research briefing of our recent work is now available online at @Nature! "Fat keeps metabolism in tune and on time using an inflammatory immune protein" nature.com/articles/d41586-0…

Fat keeps metabolism in tune and on time using an inflammatory immune protein

Nature - Immune cells that release the molecule IL-17A help to drive the metabolic rhythms of fat.

nature.com
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Scientists from @tcdTBSI and @Princeton have identified an immune molecule that keeps metabolism in tune and on time, which hints at why shift workers and others with irregular work, eating, or sleep patterns fall out of metabolic sync. Read more at: tcd.ie/news_events/articles/…
A young woman's face is illuminated in the dark by blue light from a computer screen.

ALT A young woman's face is illuminated in the dark by blue light from a computer screen.
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