Composing DNA / Professor and Department Head @ MIT Biological Engineering

MIT
Plant and soil microbe engineering is a rapidly growing field. This "review" was written as a comprehensive guide to their genetic engineering, from the idiosyncrasies of promoter design to whole genome synthesis. pubs.acs.org/doi/10.1021/acs…
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Awesome news today -- @sunyesf scientists are de-extincting lost American trees! @USDA just approved a genetically modified version of one of the great American trees, the American Chestnut, that went effectively extinct due to an Asian fungal blight introduced in 1904 that killed 3-4 BILLION trees (some 120 feet tall) by 1950. By adding in one gene from wheat to the American Chestnut genome, conservation scientists at @sunyesf have shown they can make the American Chestnut resistant to the fungal blight and revive and bring back this American classic. Let's finish this approval by @EPA and get these planted so our kids can visit these forests!!!
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1/ Let’s face it: we synthetic biologists are control freaks. We want every component to do exactly what we intend and nothing else. Our new paper asks what happens if we stop fighting biological “messiness”. @DukeBiodesign @DukeUBME nature.com/articles/s41467-0…
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Meet MIT’s next generation of engineering talent at the BE & ChemE Career Expo on Oct. 20, 2026. Connect with undergraduates, PhD candidates, and postdocs from across MIT. Priority registration rates end Sept. 20—register today: ow.ly/gaXW50ZAWM3
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Voigt Lab researchers have engineered bacteria that can function as transistors, allowing the team to create living “circuit boards” that can be printed onto a growth medium in a Petri dish. ow.ly/ouEW50ZAH9u @Geneticdesigner @nchembio
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Boyden Lab researchers have developed a method for imaging neuron activity in the zebrafish brain. Each colored spot (green and yellow) represents an active neuron. ow.ly/AGyh50ZzSUf @naturemethods
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1/6 🧬 Big news in genomics & synthetic biology! We @huijin6418 @BenLehner present the complete mutagenesis of both the genome and proteome of the bacteriophage ΦX174! 📖 Read the full preprint on @bioRxiv here: doi.org/10.64898/2026.07.25.…
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Direct protein sequencing via nanopores is hard. Peptides move fast. So glue the protein to the pore so it can't move + use an enzyme to cleave off one amino acid at a time. Each amino acid can then be measured 100s of times. They sequenced a 22 a.a. protein with 98% accuracy!
New Huang lab publication at Nature. Our newly developed technique: transient Pore Analyte Looping (tPAL) now achieves “chop and measure” nanopore sequencing of peptide, in an amino acid by amino acid manner. nature.com/articles/s41586-0…
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Who's up at BATS? Bishal Thapa (@Geneticdesigner): “Engineering Radiation Tolerant Fungi for Space Biomanufacturing” Blythe Irwin (Birnbaum & DeKosky Labs): “Introducing RePLiCA: A Replication-Based Protein:Ligand Cellular Activation Assay”
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Exhibition Features Gene-edited Glowing Plants in China 💡🌱🧬 🔗isaaa.org/kc/cropbiotechupda… #Avatar #CRISPR #bioluminescent
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Mesmerizing light sheet imaging of neutrophils swarming at a yeast target! The neutrophils were labeled with SPY650-DNA (yellow) and a calcium dye (blue). This movie is part of the recent manuscript by Evelyn Strickland that we highly recommend reading! biorxiv.org/content/10.64898…
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How Ancient Roman Automatic Doors Worked 🤔
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Prof. Hamilton Smith at J. Craig Venter Institute, a Nobel laureate for discovering type II restriction enzymes, passed away last night. A huge loss in Science, but his legacy will be remembered. @JCVenterInst @NobelPrize jcvi.org/about/hamilton-smit…
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The Novo Nordisk Foundation is looking for a Head of Natural Sciences. You would be responsible for setting the strategic direction for the natural science activities, including energy-related and interdisciplinary research. The position is in Copenhagen. apply.workable.com/novonordi…
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Coming soon to a field near you!
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On June 16, 1980, the U.S. Supreme Court ruled, in the case of Diamond v. Chakrabarty, that living organisms are patentable. It was a narrow 5-4 decision, but it laid the legal foundations for the entire biotechnology industry. (From the Archives) The First Patented G.M.O. Read & subscribe! press.asimov.com/articles/gm…
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