Dedicated to innovation in research, teaching, and learning in chemistry and chemical biology.

Cambridge, MA
Harvard Chemistry retweeted
When it comes to modulating cereblon for TPD, the future is allostery 🫡. Read more about this intersection of allosteric modulation and target protein degradation in our latest review by Vanessa 🥂, out now in @ACSCentSci! 💙 #thefutureisallostery doi.org/10.1021/acscentsci.6…
4
19
1,262
Harvard Chemistry retweeted
We posted a preprint on all-to-all functional mapping of a cortical microcircuit in vivo. biorxiv.org/content/10.64898… Yitong Qi developed molecular tools, optics, and protocols for massively parallel optogenetic stimulation and voltage imaging during animal behavior.
2
49
184
12,299
Harvard Chemistry retweeted
In the 1950s, Lipscomb & colleagues unpicked the structures of several boranes using low-temperature x-ray crystallography, determining they shared two electrons across three atoms. This accounted for boranes’ unusual geometry & unexpected dipole moment. chemistryworld.com/news/fift…
5
14
2,694
Harvard Chemistry retweeted
Thank you @Harvard for featuring our fitness landscape design (FLD) work in "How to build an evolutionary trap for viruses"! Read the article in the FAS current below: current.fas.harvard.edu/stor…
2
5
16
1,620
Harvard Chemistry retweeted
We wrote a tutorial guide on voltage imaging, now out in Neuron: authors.elsevier.com/a/1nlgh…. Indicators, microscopes, and software have all advanced to the point that it's not so hard -- you can now directly watch the electrical activity of neurons in live animals or in culture.
2
41
176
15,219
New #research: How your cells make a molecule you can buy as a supplement, CoQ10 current.fas.harvard.edu/stor… #chemtwitter
1
1
4
934
Congratulations to @brian_b_liau on winning the 2027 Tetrahedron Young Investigator Award For Bioorganic and Medicinal Chemistry! #chemtwitter sciencedirect.com/journal/te…
16
3,160
Harvard Chemistry retweeted
Competing species/strains lead to noisy, complex evolutionary trajectories. It's difficult to extract genotype fitnesses from experimental time series or population-level sequencing data. Until now! All you need is 1 equation: doi.org/10.64898/2026.07.18.… Useful for experiments! 1/N
1
6
17
1,844
RT @OnoInitiative: The 2026 Ono Initiative Award is presented to @BalskusLab, @brian_belardi, @AChemSynBio as noted. Congratulations! Emily…
1
20
@HarvardCCB is pleased to announce that leading chemist Jeffrey R. Long (Holm Lab alumnus) will be joining our department as the inaugural Thomas C. Foley Professor of Energy and the Environment: current.fas.harvard.edu/stor… #chemtwitter
12
102
4,667
Harvard Chemistry retweeted
I’m thrilled to announce Fitness Landscape Design (FLD), the first protocols for reshaping protein evolution to fight disease! FLD can proactively suppress viral fitness trajectories before mutations even arise. @Harvard @MIT Today in PNAS: pnas.org/doi/10.1073/pnas.26… MORE SOON!
2
3
10
904
Harvard Chemistry retweeted
How can microbes🦠 evolve drug 💊resistance without weakening drug binding? And how do chaperones decide which proteins to recognize? (1/n)
1
3
9
711
NEW: Professor Xiaowei Zhuang has been awarded the 2026 Dickson Prize in Medicine, @pitt_medicine's highest honor: medschool.pitt.edu/news/xiao…
2
10
168
13,405
Harvard Chemistry retweeted
Pour a glass of champagne AND red Bordeaux—Our newest work with @GSK and @scrippsresearch is out in @Nature, where we describe SB-405483, the first allosteric CRBN ligand which potentiates neosubstrate degradation. Congrats Vanessa and all authors! 🍷💫💐 nature.com/articles/s41586-0…
4
13
71
12,410
Harvard Chemistry retweeted
Our study on discovering cooperative catalysis is in print @Nature! With @JacobsenLab @eugene_e_kwan @Merck @RichrdLiu we use simple math-based pooling/deconvolution to uncover useful catalyst combinations with minimal experiments Read for free! rdcu.be/eN5i5
4
18
2,484
Harvard Chemistry retweeted
The 2026 #ErnestSolvayPrize goes to Prof. Xiaowei Zhuang from Harvard University and Howard Hughes Medical Institute. Her pioneering work in advanced cellular imaging lets scientists map and visualize the inner organization of cells and tissues at the molecular level, revealing how the body responds to a change and where this response takes place. This is science that pushes boundaries and helps build a more sustainable, connected and human future. 👉 Discover more: bit.ly/3Nnlrwm #Syensqo #SyensqoFund
1
1
6
1,310