Yaser Hashem@Hashemyaser4

Group leader (Ph.D.) at the Inserm, in the fields of molecular and structural biology.

 Bordeaux, France
hashem-lab.fr
Joined January 2019
201 Photos and videos
It's a great pleasure to share our latest collaborative work detailing the composition and structure of the highly rRNA-fragmented mitoribosome from Apicomplexa, such as Plasmodium falciparum and Toxoplasma gondii, now out in @NatureComms rdcu.be/d3R8C
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Korostelev Lab@KorostelevLab
Oct 25
We find that 5MP proteins promote high-fidelity initiation by binding 48S scanning complex to bypass weak start codons. We propose renaming them eIF1S (euk initiation factor 1 scanning). Great collab w/ @grigoriefflab.bsky.social Congrats to all authors! science.org/doi/10.1126/scia…
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Chris H. Hill@chillzaa
Aug 11
🚨 👇 Come and join us in York as a new lecturer (assistant professor) in cryo-ET! This is a research and teaching appointment to the York Structural Biology Laboratory (YSBL). From my experience it's a great place to start a group. Please share widely! jobs.york.ac.uk/vacancy/lect…
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We used cryo-EM to characterize five TRPV3 mutants causing severe genodermatosis Olmsted syndrome (OS). Our results highlight conserved TRP channel gating mechanisms, uncover the molecular basis of OS and provide a guide for future therapeutic strategies. nature.com/articles/s41467-0…
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Sergej Djuranovic
@DjuranovicLab
Jun 5
It is a great privilege to be named Mencoff Family RNA Research Professor of Molecular Biology, Cell Biology and Biochemistry at Brown University. I am grateful to Samuel M Mencoff and Mencoff Family, Brown University, Department of Molecular Biology, Cell Biology, and Biochemistry and Guiliani RNA Center at Brown for this honor. Djuranovic lab will soon celebrate their first year at Brown University.
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Sergej Djuranovic
@DjuranovicLab
Jun 3
Fresh out of the press today. Great colaboration with @slavicaPD and @Mak_Mitreva labs as well as multiple other ones involved in this project. nature.com/articles/s41467-0…

Transgenic hookworm secretes anti-tetrodotoxin human single chain antibody

Nature Communications - Biologics and protein-based drugs often require frequent, costly injections. Here, authors have engineered a hookworm to continuously produce and secrete a therapeutic human...

nature.com
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Officially out in Nature Communications: Structures of the most abundant AMPA receptor di-heteromer in the brain GluA1/A2 in the closed, open, and desensitized states! @shantigangwar @MariaKarela3 @LauraYen42 @MKCMU nature.com/articles/s41467-0…
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Sergej Djuranovic
@DjuranovicLab
Mar 18
Visit from a friend and great colleague from Newcastle University. Sergey Melnikov will after snowy February in Providence talk tomorrow about hibernating ribosomes. Another talk at Brown RNA Center. #ribosomes #RNA
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Manidipa Banerjee Lab@mblab_iitd
Feb 24
Dr. Hashem delivered a lecture on "Automated methods for data collection" on the second day of the @EMBO Practical Course: CEM3DIP 2026. @Hashemyaser4 @sathi_iitdelhi @iitdelhi
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Manidipa Banerjee Lab@mblab_iitd
Feb 24
Dr. Hashem also delivered a research talk on "Piecing together rRNA-fragmented mitochondrial ribosomes" on the second day of the @EMBO Practical Course: CEM3DIP 2026. @Hashemyaser4 @sathi_iitdelhi @iitdelhi
Manidipa Banerjee Lab@mblab_iitd
Feb 24
Dr. Hashem delivered a lecture on "Automated methods for data collection" on the second day of the @EMBO Practical Course: CEM3DIP 2026. @Hashemyaser4 @sathi_iitdelhi @iitdelhi
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Manidipa Banerjee Lab@mblab_iitd
Mar 1
An excursion to the Taj Mahal, Agra was organised for the eighth day of the @EMBO Practical Course: CEM3DIP 2026.
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Nature Chemical Biology@nchembio
Jan 13
RNA capped with dinucleoside polyphosphates has been recently discovered in bacteria and eukaryotes. A new paper provides a structural explanation of how dinucleoside polyphosphates initiate RNA transcription nature.com/articles/s41589-0…
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Programmable initiation of mRNA translation by trans-RNA go.nature.com/3K7SEdO
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It is a great pleasure to have been part of this cutting-edge project by the Shu-Bing Qian lab (Cornell), just published in @NatureBiotech 🥳🥳🥳 Amazing work leading to the development of a Programmable initiation of mRNA translation by trans-RNA nature.com/articles/s41587-0…
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Tremendous effort by Longfei Jia, Tan-Trung Nguyen, Saori Uematsu, Yifei Gu and Shengcho Shi and of course most significantly the brain child of Shu-Bing Qian 👏👏👏👏 Boy what a project it has been!
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Special thanks to the @ERC_Research on my side for the funding (Condolidator grant 101088541 SPICTRANS), @iecb_bordeaux cryo-EM platform and the @Inserm for the ongoing support.
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