Associate Professor at UCSF. Opinions are my own. He/him.
San Francisco, CA
- Tweets 677
- Following 436
- Followers 1,432
- Likes 3,080
Ian Seiple retweeted
Is 2026 the year of arginine?
Covalent discovery and chemical proteomics have largely focused on cysteine and lysine, leaving other functionally critical residues underexplored.
In our new preprint, our joint Seiple and Zaro Lab team asked: Can arginine be targeted covalently? 🧵
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Ian Seiple retweeted
Get ready for a 6-part series on #antibacterial development news highlights, editorialized by yours truly! In Part 1, I've contextualized live biotherapeutic products in the C. difficile therapy landscape.
Give it a read & a comment so we can all learn.
linkedin.com/pulse/thematic-…
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Weight set / power rack I built during lockdown. The only things that didn't come from the hardware store were the bar, the bench, and the clips. Fun project, and still using it 3 years later!
#ChemistsWhoLift
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Back on twitter with a ✨shimmer✨ Follow @theseiplelabucsf on “tick tock” #TikTok #chemtwitter #realtimechem tiktok.com/t/ZTR94oMgX/
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Ian Seiple retweeted
Jumping around the mutation alphabet to hit cancer! Our new work covalent targeting of KRAS G12S is online: nature.com/articles/s41589-0… Interested in more? The Zhang lab (thezlab.org) at @UCBerkeley is recruiting:)
#G12S The Next #KRAS oncogene targeted by covalent chemistry by @bignerdzzy who just started his lab @UCB_Chemistry (thezlab.org). Next up G12R. nature.com/articles/s41589-0…. @UCSFCancer @HHMINEWS @UCSF
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Ian Seiple retweeted
The recent @ASMicrobiology paper entitled "Leaks in the Pipeline: a Failure Analysis of Gram-Negative Antibiotic Development from 2010 to 2020" is a must read.
Check it out now!
@nehakprasad9 @IanSeiple
#FireExtinguishersOfMedicine
#AMRSOS #StopSuperbugs
amr.solutions/ai.php?card=yj…
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Ian Seiple retweeted
✨ One of our most read articles in the last 12 months! ✨
Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1 by Cotton, Nguyen, Gramespacher, @IanSeiple & @realJimWells
🔓 #OpenAccess fal.cn/3kHsB
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Ian Seiple retweeted
Welcome to the speakers for Monday 31st January at #MBCF2022 - you can view the full line up of 40 speakers for the 15th Winter 'Medicinal & Bioorganic Chemistry' Conference at Steamboat Springs, Colorado on the MBCF website at mbcfconference.com
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Ian Seiple retweeted
Super honored to be part of this! Just happy to be in the field with all the cheerful and bright scientists! Big thank you to my collegues and mentors who helped and supported me and my science especially @HarvardCCB @UCSF @UCB_Chemistry
Check out the amazing scientists on this list-- and noting quite a few folks on here for the drug discovery crowd to keep an eye on (like Monte Rosa's @AlabiBorteley, UCSF's @bignerdzzy, Rockefeller's @katenokv).
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This amazing work by @adamcotton92 in collaboration with @realJimWells is now published in ACS @ChemicalBiology !
See the updated story here: dx.doi.org/10.1021/acschembi…
Now includes a direct comparison of BioReACT-labeled antibodies to Halo/SNAP/CLIP fusions. Must see!
1/7 Check out our new method to selectively label biotin-containing biomolecules, BioReACT! This work all by the talented @adamcotton1992 in collaboration with @realjimwells. doi.org/10.26434/chemrxiv.13….
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Ian Seiple retweeted
.@XiaoyuShi2, Li, @IanSeiple @BoHuangLab et al. report the development of label-retention expansion #microscopy w/ a set of trifunctional anchors that not only prevent fluorescent signal loss but also enable high-efficiency labeling using SNAP & CLIP tags. bit.ly/3qR6vXX
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Ian Seiple retweeted
Very humbled and honored to be included among this stellar group of scientists that includes my friend @IanSeiple and former UC Davis trainee @gutierrez_lab
The Dreyfus Foundation announces the selection of 16 Camille Dreyfus Teacher-Scholars for 2021. These young faculty have each created an outstanding independent body of scholarship, and are deeply committed to education. For details on the awardees, see dreyfus.org/2021-camille-dre…
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I’m so incredibly honored to be included in this list! Thank you Camille Dreyfus!
The Dreyfus Foundation announces the selection of 16 Camille Dreyfus Teacher-Scholars for 2021. These young faculty have each created an outstanding independent body of scholarship, and are deeply committed to education. For details on the awardees, see dreyfus.org/2021-camille-dre…
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Ian Seiple retweeted
The Dreyfus Foundation announces the selection of 16 Camille Dreyfus Teacher-Scholars for 2021. These young faculty have each created an outstanding independent body of scholarship, and are deeply committed to education. For details on the awardees, see dreyfus.org/2021-camille-dre…
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