This account is inactive. Find us at: linkedin.com/in/led3hub/ @led3hub.bsky.social @LED3hub@mstdn.science
@LeidenScienceEN @UniLeiden
- Tweets 304
- Following 8
- Followers 390
- Likes 235
Great to see that our LED3 Lectures and Events are now also advertized on the new screens throughout the Gorlaeus Building of our Faculty @LeidenScienceEN. Hopefully some new people will see them and come to our exciting talks!
universiteitleiden.nl/en/sci…
1
46
We are happy that @Kelly_Chibale will give a lecture within our @LeidenScienceEN Faculty-wide Tuesday Talk Series on February 4th at 4 p.m. in room CM1.26: "Tailoring medicines for the genetically diverse African populations". Free registration required. staff.universiteitleiden.nl/…
2
3
266
We are excited to host Andrea Rentmeister @RentmeisterLab for a LED3 Lecture on February 13th at 4 p.m. in CM1.26 of the Gorlaeus buidling. She will talk about "Harnessing Methylation: Chemical and Metabolic Tools for Analyzing and Regulating mRNA".
If you are in Leiden, come by!
2
99
A new @biorxivpreprint by the group of Sander van Kasteren presents an automated processing pipeline for the Glyco-PAINT Technology (Glyco-PAINT-APP) that allows studying the binding of lectins to their ligands with subcellular resolution in primary cells. biorxiv.org/content/10.1101/…
1
1
142
We are very excited that the LED3 & LUCID symposium "Drug Discovery & Global Health" has obtained a lot of ineterest. Registration for in-person attendance is full, but you can now register for virtual attendance. universiteitleiden.nl/en/eve…
1
2
164
We are happy that @Kelly_Chibale will give a lecture within our @LeidenScienceEN Faculty-wide Tuesday Talk Series on February 4th at 4 p.m. in room CM1.26 on "Tailoring medicines for the genetically diverse African populations". Free registration required.
medewerkers.universiteitleid…
1
1
195
We are very excited to see the huge interest in the symposium "Drug Discovery & Global Health" that we are co-organizing with LUCID.
Sadly, the in person registration is already full. We are working on an option to attend virtually and will update you as soon as possible.
2
96
LED3 hub member Mario van der Stelt represented our network with a great Tuesday Talk at the New Year's Reception of our Faculty of Science @LeidenScience. He talked about his research into better understanding the human brain on the example of endocannabinoid signalling.
2
3
549
The @LED3hub is very excited to be a key part of the research theme "Drug Disovery and Development" that was together with the other 5 research themes highlighted by our dean Jasper Knoester as an important priority for the faculty @LeidenScience at the New Year Reception.
1
1
275
We are very excited to announce the @LED3hub & LUCID Symposium "Drug Discovery and Global Health" on February 6th with keynotes @Kelly_Chibale and Paola Picotti @Picotti_Lab as well as an amazing lineup of further speakers. Free registration is required. universiteitleiden.nl/en/eve…
1
4
729
The @LED3hub wishes you a great start to the new year 2025!
We are looking forward to some great events including the LED3 & LUCID Symposium "Drug Discovery and Global Health" (universiteitleiden.nl/en/eve…) and the remainder of the 2024/2025 LED3 Lectures (universiteitleiden.nl/en/sci…).
3
3
568
We are very excited to announce the @LED3hub & LUCID Symposium "Drug Discovery and Global Health" on February 6th with keynotes @Kelly_Chibale and Paola Picotti @Picotti_Lab as well as an amazing lineup of further speakers. Free registration is required. universiteitleiden.nl/en/eve…
1
5
11
1,271
We are very happy to be hosting the @LED3hub Lectures of this academic year with an amazing lineup of speakers. If you are interested, you are very much invited to join us in Leiden for these exciting lectures. universiteitleiden.nl/en/sci…
4
5
648
The @LED3hub was represented by Anthe Janssen at the Oncode Accelerator "Building Bridges: The future of developing small molecule-based cancer therapeutics" webinar. He talked about the power of AI to accelerate the drug discovery process.
2
2
376
Sadly, the LED3 Lecture on this coming Thursday, November 28th, by Tjeerd Barf had to be cancelled. The next LED3 Lecture will be on February 6th by Paola Picotti. We are hoping to see many of you there.
universiteitleiden.nl/en/sci…
1
605
Sebastian Geibel @GeibelLab represented the LED3hub at the #ReedijkSymposium. He talked about the importance of keeping up research into new treatments for tuberculosis and about his research into the mycobacterial type VII secretion systems as a potential drug target.
2
3
294
Zach Armstrong @Armstrong_CBio represented the @LED3hub with an interesting lecture about his group’s research at the #ReedijkSymposium. He gave exciting insights into pharmacological chaperones that stabilize mutant enzymes for the treatment of lysosomal storage diseases.
2
4
281
Zach Armstrong @Armstrong_CBio of the @LED3hub today gave a talk at the new Leiden Seminars in Biophysics and Structural Biology of @UniLeiden. He talked about studying human fucosidase and heparanase with chemical and structural biology methods.
2
3
354
There is an open PhD position within the @LED3hub!
For an interdisciplinary project involving chemical synthesis, chemoproteomics and immunology, Madeline Kavanagh @mads_chem is looking for a PhD that will develop chemical probes to study immune regulation drive.google.com/file/d/11Mh…
1
4
771
If you are one of the many, who have recently joined @bluesky, find us there as @led3hub.bsky.social.
We also created a starter pack of the members of the LED3 hub. Follow our scientists to hear more about their exciting science. bsky.app/starter-pack/led3hu…
2
1
1,092
We are looking forward to having Andrew Leach for a @LED3hub Lecture on Thursday, October 24th, at 4:00 p.m.
He will give us insights into his efforts to "Democratize Drug Discovery with Open Data".
If you are interested, make sure to come by!
universiteitleiden.nl/en/sci…
4
5
1,327
We are looking forward to having Andrew Leach for a @LED3hub Lecture on Thursday, October 24th, at 4:00 p.m.
He will give us insights into his efforts to "Democratize Drug Discovery with Open Data".
If you are interested, make sure to come by!
universiteitleiden.nl/en/sci…
4
4
1,106
We are very happy that Emily Balskus @BalskusLab visited us today for the first @led3hub lecture of the academic year. She gave an exciting overview of her group's research into using chemistry to better understand the human gut microbiome.
1
5
385
In his lecture, Prof. Ruedi Aebersold gave an insightful overview of the systems biology of a cell and how different technologies are needed to get a holistic picture of how cells work as Complex Adabtable Systems controled on the protein level. (3/4)
1
98
In his lecture, Prof. Matthias Mann showcased the importance of machine learning for the further development of proteomics as well as his group's impressive contributions towards bringing proteomics to the bedside to better understand human diseases and identify biomarkers. (2/4)
1
91
The @LED3hub was very excited to host the two winners of the Dr H.P. Heineken Prize for Biochemistry and Biophysics 2024 (@hein_prizes), Prof. Ruedi Aebersold and Prof. Matthias Mann @labs_mann, in front of a full lecture hall at @LeidenScienceEN. (1/4)
1
2
10
3,030
This week we are kicking of the @LED3hub Lectures of this academic year. We are very excited to again have an amazing lineup. If you are interested , you are very much invited to join us in Leiden for these exciting lectures. universiteitleiden.nl/en/sci…
1
4
10
1,714
We are looking forward to having @BalskusLab for a @LED3hub Lecture on Thursday, September 26th, at 4:00 p.m.
She will give us insights into her group's work to discover, understand and manipulate microbial natural product synthesis pathways.
If you are interested, come by!
1
2
2,059
We are excited to host the awardees of the Heineken Prize, Matthias Mann @labs_mann and Ruedi Aebersold, for lectures on Wednesday at 10:00 a.m.
If you want to hear about their groundbreaking work on proteomics to better understand biological systems, make sure to come by.
5
18
2,051
The @LED3hub was well represented at #EMBOChemBio.
Julia Pols, Marnix Roseboom and Miguel Mata presented their work on a poster, Julia presented a Flash Talk and Miguel won one of the poster awards. Congratulations!
Thank you for representing our @LED3hub at this event!
1
3
7
1,324
We are very happy to again have an amazing program for the #LED3Lectures 2024/2025 of the @LED3hub. If you are interested , you are very much invited to join us in Leiden for these exciting lectures. universiteitleiden.nl/en/sci…
3
8
2,070
Can you improve an antibiotic that has been in clinical use for 75 years?
The group of @NatMart_Chembio of the @LED3hub addressed this question by developing bacitracin analogs with enhanced activity against vancomycin-resistant enterococci (VRE).
pnas.org/doi/10.1073/pnas.23…
3
12
673
At the #LED3Symposium, we also announced next year's #LED3Lectures with an amazing program including @BalskusLab, Andrew Leach, Tjeerd Barf, @Picotti_Lab, @RentmeisterLab, Jeff Kelly, @johnpoverington, Kim Lewis, @TateScience and @jaykeasling.
6
10
4,152
We had an amazing day with a lot of exciting, interdisciplinary science at the #LED3Symposium. Over 120 participants took part in our event and learned a lot about early drug discovery projects across the @LED3hub institutes @LeidenScienceEN @LeidenScience @UniLeiden.
3
5
468
The final keynote lecture of the #LED3Symposium was given by @NatMart_Chembio. He talked about his group's amazing research into inhibitors of the cancer driver protein Nicotinamide N-methyltransferase (NNMT). sciencedirect.com/science/ar…
2
4
489
Great talk by Sophie Wintermans at the #LED3Symposium. She talked about her PhD research in the group of @Martola1985 into a high throughput screening method for RNA-binding small molecules on the example of the PreQ1 riboswitch. biorxiv.org/content/10.1101/…
2
2
465
Interesting talk by Majlen Dilweg at the #LED3Symposium. She talked about her PhD research on norepinephrine re-uptake inhibitors. Interesting insights into stereoselective synthesis of new highly potent inhibitors.
1
1
293
Great science at the Flash Talk session of the #LED3Symposium. Amazing to see all the diverse topics including antibiotics, cyclic peptides, GPCRs, genome mining, hydrogels, covalent inhibitors and many more that are covered in interdisciplinary projects within the @LED3hub.
2
4
442
Great talk by Nataliia Machushynets at the #LED3Symposium. She talked about her research in the group of @GillesvanWezel into new tridecaptin antibiotics with enhanced biological activity. An exciting interdisciplinary project across several @LED3hub groups.
4
3
911
Great start to the afternoon session of the #LED3Symposium. Laura Heitman @Heitman_lab talked about her group's work on insurmountable antagonists for GPCRs on the example of CCR2. Great insights into a covalent inhibitor and ways to thoroughly investigate its mechanism.
1
1
897
It was great to see all the lively discussions between researchers from all of our institutes at the poster session of the #LED3Symposium. We had a very high quality of posters with an amazing diversity of topics and a lot of interdisciplinary connections.
2
4
428
Interesting talk by Gijs Ruijgrok at the #LED3Symposium. He talked about the research of the group of Hermen Overkleeft on mechanism-based heparanase inhibitors to combat metastasis formation in vivo and how they further explore this at AVIGI therapeutics. doi.org/10.1073/pnas.2203167…
1
2
285
Interesting talk by Elma Mons at the #LED3Symposium. She talked about her postdoctoral research in the group of @NatMart_Chembio into the preclinical development of guanidino lipoglycopeptide antibiotics with potent activity in vitro and in vivo.
1
3
1,134
Great talk by @DaanvanderVliet at the #LED3Symposium. He talked about his PhD research in the group of @mariovdstelt into the pathologies of multiple sclerosis (MS) lesions using an impressive, interdisciplinary multiomics approach in collaboration with @LACDR and @NBB_BrainBank.
1
2
6
347
Great talk by Jan Pascal Kahler @KahlerJp at the #LED3Symposium. He talked about his postdoctoral research in the group of @PomplunSeb into chemically tailored protein therapeutics for targeting the cancer master regulator Myc in cells. biorxiv.org/content/10.1101/…
3
8
407
The #LED3Symposium is off to a great start with an exciting keynote lecture by @Martola1985. She talked about her group's research into the rational design of glycosidase inhibitors to address different diseases. pubs.rsc.org/en/content/arti…
1
3
256
Thank you to @SeanMcK27 for presenting the @YoungSciNet of @EuroMedChem at the #LED3Symposium. He made compelling arguments to join the network including great networking opportunities, exciting trainings, support for young scientists as well as a lot of great events and prizes.
1
2
340
Bart de Smit, vice dean of @LeidenScience @LeidenScienceEN, opened the @LED3hub PhD/postdoc symposium #LED3Symposium. Great to see him highlight the importance of LED3 as a central hub for interdisciplinary collaborations within the Faculty of Science @UniLeiden.
1
1
285
The organizers of the 1st @LED3hub PhD/postdoc symposium #LED3Symposium (@CharlotteHijma2, Sophie Wintermans, Rik Remmers, @NedBuijs, @pasteldemata) are done with the preparations and excited to welcome the particpants. Thank you very much for all the great work on this event!
4
3
1,298
NEW PAPER ALERT! A team around the @LED3hub groups of @mariovdstelt, @NatMart_Chembio and @GillesvanWezel published a new antibiotic against Gram-negative bacteria in @NatureChemistry. It binds a new site on gyrase and overcomes fluoroquinolone resistance. rdcu.be/dLgV4
5
7
1,542
We are very excited to host the first @LED3hub PhD/postdoc symposium #LED3Symposium on Thursday, June 20th. We are looking forward to keynotes by @Martola1985, @Heitman_lab and @NatMart_Chembio and especially to many talks and posters by our PhD and postdoc researchers.
5
7
2,096
We are excited that Sarah O'Connor @OConnor_lab @MPI_CE visited us today for a @LED3hub Lecture. She talked about her group's research into "Harnessing the chemistry of natural product biosynthesis". Great insights into the diversity of plant natural products and their evolution.
1
3
621
We are very excited that Sarah O'Connor @OConnor_lab will visit us for this week's @LED3hub Lecture. On Thursday at 4 p.m., she will be talking about "Harnessing the Chemistry of Natural Product Biosynthesis" in room 1.5.31 of the Sylvius building @LeidenScienceEN @UniLeidenNews.
2
4
992