🎉 And we’re off: #EMBLRBP has officially begun! Scientific organiser Matthias Hentze set the stage for an incredible few days ahead.
Kicking things off in the best way possible, Elena Conti and Anthony Hyman delivered two fantastic keynote lectures! 🤩
Excited to share our latest research on co-translational mRNA decay by the exosome in human cells! We uncover how the exosome-SKI complex is recruited to ribosomes and propose a novel role for SKI in recognizing collided disomes. @MPI_Biochem
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Excited to share our latest research on co-translational mRNA decay by the exosome in human cells! We uncover how the exosome-SKI complex is recruited to ribosomes and propose a novel role for SKI in recognizing collided disomes. @MPI_Biochem
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Yesterday, @carovinuesa was awarded the Axel Ullrich Medal. In an inspiring #lecture she presented her findings on using #genomics to understand #autoimmunity as well as her contributions to the case of a mother wrongly convicted of killing her children. Thank you, @carovinuesa
@LabConti at @MPI_Biochem uncovers a two-anchor points recruitment of PAPOA to the #polyadenylation machinery whereby PAPOA C-ter gets displaced from its core by FIP1 and can interact with CPSF160.
bit.ly/49KR603
Excited to share our latest research on the cleavage and polyadenylation machinery! Big congratulations to @SofiaTodesca and the entier team for their hard work! @MPI_Biochem@RNAJournal
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Lovely talk and scientific story from @SofiaTodesca from @LabConti at #RNA24 Her study providing insight into how the poly(A) polymerase is recruited will be appearing soon @RNAJournal@RNASociety This impressive AM session shows the future of science is bright! #WomenInSTEM
Heartfelt congratulations to @ingmarschafer on his promotion to Professor! Your presence will be greatly missed, but we are excited for the impact you will continue to make in your new position. Wishing you nothing but the best on your journey ahead! 🎉🥳🚀 #PLID#ZML#Dresden
Have a look at our new manuscript! Multiple conformational states of the Ski complex reveal a direct interaction of Ski2 with the exosome during RNA handover. Congratulations all! 👇👇👇
Happy to share our latest work on cytoplasmic mRNA degradation by the Ski-exosome assembly. We reveal via SPA cryoEM how different conformational states of the Ski complex are connected to exosome recruitment and RNA handover. Thanks to everybody involved @LabConti@MPI_Biochem
Thank you to our close collaborator for many years Professor Elena Conti @LabConti from @MPI_Biochem for stopping by our department to give a talk before receiving an honorary doctorate later today at @AarhusUni. @NatSci_AU
Learn about the life and death of mRNA and why this is a big deal.
2023 Kafatos Lecturer and world-renowned biologist Elena Conti will discuss the molecular marvels that govern our cellular mRNAs in Munich on 20 October. Open & free to the public.
embl.org/news/alumni/decidin…
Our new study exploring the molecular principles governing packaging of eukaryotic mRNPs has just come out in @GenesDev .
We find evidence for RNA packaging and compaction relying on positively charged IDRs of potentially many RNA binding proteins. Interested? Check it out!