Group Leader at the Cambridge Stem Cell Institute @SCICambridge. Interested in epithelial cell fate plasticity, stem cell biology and early tumorigenesis.
Cambridge, UK
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🚨 New paper from our lab just published in Nature🚨nature.com/articles/s41586-0…
Discover how 🌱 tumour formation is shaped by tissue context from the very beginning.
✨Fantastic team led by @GSkrupskelyte, Eduardo Rojo, Harikrishnan Ajith
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Maria Alcolea retweeted
It is finally out 😍Check it out!! Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning: Cell cell.com/cell/fulltext/S0092… @CSchwayer @Silvia_Bar01 @d_brueckner @EdouardHannezo
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This is a lovely smiley face! 😊✨ Super excited to finally see our recent paper in print! 📖🎉 Check out how the precancerous fibrotic niche 🌱 determines nascent tumour persistence in the current issue of @Nature 🔬🧫
nature.com/articles/s41586-0…
@GSkrupskelyte, E.Rojo, @hk_ajith
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Excited to see our work featured @Cancer_Cell✨
🌱 Thanks for highlighting our work on how nascent tumours survive by engaging epithelial-stromal feedback to build a “precancerous niche” that supports their long-term persistence👩🔬
nature.com/articles/s41586-0…
cell.com/cancer-cell/fulltex…
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Huge thanks to @Co_Biologists for featuring our latest work! 🧬
We’re thrilled to partner with @focalplane_jcs to share the "behind-the-scenes" 🔬 of studying what determines early tumour persistence and fitness🦀.
nature.com/articles/s41586-0…
(@GSkrupskelyte, Eduardo Rojo)
Tracking nascent tumours in their earliest stages is one of the biggest hurdles in our field. In the latest blog post by Focal Plane, we break down the specific challenges encountered in this journey.
focalplane.biologists.com/20…
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Maria Alcolea retweeted
New in @Nature : Early tumours persist by co-opting fibroblasts to build a fibronectin-rich pre-cancer niche. Disrupt the dialogue → up to 82% fewer persistent lesions. A fresh stromal perspective on cancer initiation from @MariaPAlcolea ’s lab. Must-read!
🚨 New paper from our lab just published in Nature🚨nature.com/articles/s41586-0…
Discover how 🌱 tumour formation is shaped by tissue context from the very beginning.
✨Fantastic team led by @GSkrupskelyte, Eduardo Rojo, Harikrishnan Ajith
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Thanks for featuring our work on how emerging tumour remodel their nascent niche 🌱promoting their survival @Cambridge_Uni, @SCICambridge, @CRUKCamCentre, @PDN_Cambridge
stemcells.cam.ac.uk/news/alc…
✨@GSkrupskelyte, Eduardo Rojo, Harikrishnan Ajith
nature.com/articles/s41586-0…
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🚨 New paper from our lab just published in Nature🚨nature.com/articles/s41586-0…
Discover how 🌱 tumour formation is shaped by tissue context from the very beginning.
✨Fantastic team led by @GSkrupskelyte, Eduardo Rojo, Harikrishnan Ajith
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Immense gratitude to the whole team who worked tirelessly to make this happen, especially our fantastic collaborators Ayesha Noorani, Sebastian Zeki, @Bartomeu_Colom, Jozsef Jaszai, @YitengDang, @rulandsgroup, Phil Jones, Ben D. Simons and many others.
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We are deeply grateful to our funders for their continued support including @wellcometrust, @royalsociety, @UKRI_News, @WorldwideCancer, @GutsCharityUK, @CR_UK, @ERC_Research
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🚨 New paper from our lab just published in Nature🚨bit.ly/46G8ggV
Discover how 🌱 tumour formation is shaped by tissue context from the very beginning.
Fantastic team led by @GSkrupskelyte, Eduardo Rojo, Harikrishnan Ajith
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Immense gratitude to the whole team who worked tirelessly to make this happen, especially our fantastic collaborators Ayesha Noorani, Sebastian Zeki, Jozsef Jaszai, @YitengDang, @rulandsgroup, Phil Jones, Ben D. Simons and many others.
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We are deeply grateful to our funders for their continued support including @wellcometrust, @royalsociety, @UKRI_News, @WorldwideCancer , @GutsCharityUK, @CR_UK, @ERC_Research
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Maria Alcolea retweeted
Our new review in Trends in Cell Biology : "The Wnt–NAD⁺ axis in cancer, aging, and tissue regeneration"
cell.com/trends/cell-biology…
👏 Kudos Lamprecht & Abu Sanad and 🙏 @KusumbeLab
Apologies to colleagues not cited (journal limits) + 🙏 to colleagues, reviewers & editor.
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Maria Alcolea retweeted
The latest paper @VallierLab is now online. This tour de force from the amazing Laetitia Pinte (supervised by @martavilagonz ) uncover the function of EHF in the lung (not a liver story!) epithelium using hiPSCs, genome editing, and lung organoids.
doi.org/10.1242/dmm.052106
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