Nature Cancer is a journal dedicated to publishing the latest advances across all areas of cancer research.
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📢Our September Issue is out!
Read about generative AI for digital pathology, cancer immunometabolism, GITR antibody optimization, l-glutamine combination therapy, and more
🔗nature.com/natcancer/volumes…
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Attending #ESMO26? Our Senior Editor, @Vin_Giacco, will be there and looks forward to connecting with the oncology community. Get in touch to discuss your latest research and publishing opportunities at Nature Cancer.
Looking forward to attending the #ESMO26 Annual Meeting in Madrid! I'll be there representing @NatureCancer and meeting the oncology community.
Happy to discuss your latest research, publishing opportunities, or ideas for the journal, please reach out.
See you in Madrid 🇪🇸
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🧬New in Nature Cancer:
The phase 2 PEGASUS trial explores a ctDNA-guided strategy to de-escalate or escalate adjuvant therapy in patients with high-risk stage II and stage III colon cancer, moving us closer to more personalised treatment decisions.
nature.com/articles/s43018-0…
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📢Read our Series on Next-generation cancer therapeutics featuring commissioned Reviews and a selection of articles published in Nature Cancer!
nature.com/collections/hehde…
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🚨New in Nature Cancer
Dr Gong and colleagues report findings from the phase 1 study evaluating L-glutamine + gemcitabine/nab-paclitaxel in untreated advanced PDAC. ORR 44%, including 12.5% CR, with median OS of 22 months. #PancreaticCancer @jgong15
nature.com/articles/s43018-0…
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Now Online!
The neuropeptide galanin impairs antitumor immunity in glioblastoma by interacting with its receptor GALR3 on monocytic myeloid-derived suppressor cells, promoting their infiltration and ferroptosis resistance.
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Our August issue is live!🏖️
Featuring copper dependency in AML, iron-mediated ferroptosis, GPNMB-directed CAR-T cell therapy, IDH1-mutant vaccine in phase 1 trial, and more
🔗nature.com/natcancer/volumes…
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The full agenda for Reframing Precision Medicine is now live.
We created this event with the goal of moving medicine beyond theory to show how multi-omics, AI, and big data can make truly personalised care the norm.
Join us in London: invt.io/1txbmzq1h21
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💫Online today
The Review on intratumor heterogeneity by @Jonathancmwan, @NickyMcGranahan and @CharlesSwanton
🔗nature.com/articles/s43018-0…
Check out the rest of the Series on Tumor Heterogeneity and Plasticity here: nature.com/collections/gfbbj…
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Nature Cancer retweeted
Join @NancyFGoodman, @Gilles_Vassal and 15 other global experts at our event with @StJudeResearch, looking to address urgent challenges and opportunities in childhood cancer care. Secure a seat and submit an abstract by Aug 6. go.nature.com/4sT18WF
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☀️Check out our July issue !
✅Tertiary lymphoid structures
✅DNA vaccine for GBM
✅CAR T cell therapy in lung metastases
✅adjuvant chemotherapy in nasopharyngeal carcinoma
✅neutrophil-driven contact-dependent immune suppression
✅GABA in GBM
nature.com/natcancer/volumes…
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🌟Online today
A micropeptide encoded by the lncRNA USP30-AS1 promotes tumor growth by attenuating cGAS–STING–type I IFN signaling in macrophages
nature.com/articles/s43018-0…
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Nature Cancer retweeted
Great week for the Bruno lab for publications. Check out our new commentary on #TLS in @NatureCancer
@PittTweet @UPMCHillmanCC
nature.com/articles/s43018-0…
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In first-in-human phase 1 NOA16 trial, Platten and colleagues report the long-term clinical and immunological follow-up outcomes of a vaccine targeting mutant IDH1 in persons with astrocytoma. @Platten_lab
nature.com/articles/s43018-0…
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🌻Check out our June issue !
✅Metastatic dissemination in CRC
✅Immunotherapy in GBM
✅BH3 mimetics sensitization in AML
✅ctDNA and PSA to monitor prostate cancer
✅Methylation-based CNS tumor classification
and more
nature.com/natcancer/volumes…
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Zemp at al. found GPNMB as a targetable antigen for MiT/TFE-family fusion-driven soft-part sarcoma and translocation RCC and tested GPNMB-directed CAR T cell therapy in preclinical models and in first-in-human trial.
Read the N&Vs: nature.com/articles/s43018-0…
nature.com/articles/s43018-0…
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🚨Check out our last release
Bayik and colleagues show that inhibition of GABBR signaling extends survival in female glioblastoma models, highlighting the potential for sex-specific cancer treatments and the unique immune landscape shaped by GABA
nature.com/articles/s43018-0…
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⭐️Online now
Iron level and ferroptosis impair antitumor efficacy of CAR-T cells.
by Dongrui Wang, Yongxian Hu, Pengxu Qian, He Huang & colleagues
nature.com/articles/s43018-0…
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📢Online now!
@MoritzGerstung, Felix Sahm & co developed an AI algorithm that leverages H&E slides to classify central nervous system tumors into methylation-based subtypes reducing turnaround time to 12 min in prospective evaluation.
nature.com/articles/s43018-0…
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⭐️Now online
In a large cohort of patients with ICB-treated glioblastoma, Catherine J. Wu & colleagues show that baseline mesenchymal transcriptional state predicts therapy response, and transition to non-mesenchymal state results in acquired resistance.
nature.com/articles/s43018-0…
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