New Return on Health Episode with Prof. Robert Lustig, MD! piped.video/watch?v=OeltyHXw…

Two good things about Bryan Johnson: first, I sympathize deeply with the desire to slow aging. Second, whatever one thinks of his methods, he has undeniably brought public attention to our field. That gives us an opportunity: we can explain the real scientific progress—and gently distinguish it from the noise. In nearly every interview I gave, I said that my greatest fear was that Bryan Johnson would die. Not because I wished him ill, obviously, but because some of the combinations and interventions seemed risky. I worried that if anything happened to him, people would conclude: “Well, if Bryan Johnson couldn’t make it, these aging researchers certainly can’t.” I truly did not mean to become a prophet. But now, apparently, I have been promoted from geroscientist to Cassandra—with a much worse skincare routine. nytimes.com/2026/08/21/us/br…

Check out our new Return on Health Episode with Aubrey de Grey: piped.video/watch?v=kI6Pog88…

Thanks for coming on the show!

My dads an incredibly smart man. •Great leader •Can fix anything •Socially strong & networks well •Read a book a week for 30 years He NEVER moved up in his company. I asked him WHY & the answer he gave me brought me to tears. Here’s THE BEST LESSON my dad ever taught me.

VCs doing due diligence on a pre-product AI startup founded by some Stanford bros

This has to be the biggest redflag interview process ever 🚩

EU officials sign off on a deal that effectively ends the sale of most new combustion engines from 2035 trib.al/AWDCmPQ

How much work can AI do in 30 minutes? An astonishing amount. I had it run a fake product launch for for me, and it conducted research, made strategy, created emails and social campaigns, built websites & graphics, and even did a video. All in 30 minutes. oneusefulthing.substack.com/…

Methane has 80 times the global warming power of carbon dioxide, and huge amounts spew into the atmosphere daily. @KalPenn breaks down why fixing methane leaks is one of the cheapest ways to slow global warming. Watch the full episode and more: bloom.bg/3HtndGT

I Asked The Founder of Climony, a Climate-Tech Startup, Four Questions. blog.startupstash.com/i-aske… by @nikothems for Startup Stash #climatetech #climatechange #CO2emissions

Nuclear fusion is the holy grail for limitless green energy, but will it come soon enough to avoid the worst of the climate crisis? @FryRsquared breaks down how it works and why it’s so difficult to create trib.al/GwqYsZt

🚨 BREAKING: Microsoft is releasing Copilot for Microsoft 365: - Word - Powerpoint - Excel - Teams Here's the summary:

Last night I used GPT-4 to write code for 5 micro services for a new product. A (very good) dev quoted £5k and 2 weeks. GPT-4 delivered the same in 3 hours, for $0.11 Genuinely mind boggling

I just watched @gdb use GPT-4 to: - write code for a discord bot - debug & read documenatation - look at images and describe them in detail - create website code (that works) for a site based from a pencil mockup made in a physical notebook wtf

here is GPT-4, our most capable and aligned model yet. it is available today in our API (with a waitlist) and in ChatGPT+. openai.com/research/gpt-4 it is still flawed, still limited, and it still seems more impressive on first use than it does after you spend more time with it.