Imagine a world where #pancreaticcancer is detected early, where patients are guided to the best care from the moment of diagnosis, and where discoveries move from the lab to saving lives in years, not decades. That is the future PanCAN is building — by bringing together patients, families, researchers and clinicians to transform the future of this disease. 💜 Today at #PanCANPurpleStride, we launch our most ambitious effort yet, the $250 million All Together We Can campaign. Our vision: to make survival the expectation, not the exception, for the tens of thousands of people diagnosed with this disease every year. Why now? Because this disease remains the deadliest major cancer and the only one with a five-year survival rate below 20%. Because patients and their loved ones deserve more time, more treatment options and more effective screening strategies. Because our community knows that when we’re united in purpose and vision, we can achieve anything — and we’re ready to take on this next chapter. Learn more about how, over the next five years, the All Together We Can campaign will invest across three strategic pillars — forming a comprehensive approach to accelerate progress and improve survival for pancreatic cancer patients at 🔗 pcan.at/all-together-we-can.

Register now! 1440.zoom.us/webinar/registe… Join @CanopyCancer & @PanCAN TOMORROW, 10/29 @ 2pm ET, to discuss the 1st-ever U.S. consensus statements on Exocrine Pancreatic Insufficiency (EPI) in Pancreatic Cancer Care. All registrants receive a copy of the recording after the event.

On World Pancreatic Cancer Day, join PanCAN for a Right Track Live virtual event focused on helping patients, caregivers and loved ones better understand early detection for pancreatic cancer. PanCAN Chief Scientific and Medical Officer @ABerkenblit, MD, MMSc, will host a panel of special guests: 🔎 Avinash Kambadakone, MD Radiologist, Chief, Abdominal Radiology, Mass General Brigham 🔎 Bechien Wu, MD, MPH Gastroenterologist, Physician Director, Division of Clinical Research, Kaiser Permanente 🔎 Nipun Merchant, MD (@NbmerchantMD) Surgeon, Vice Chair of Surgical Oncologic Services, University of Miami Miller School of Medicine 🔎 Diane Simeone, MD (@MadameSurgeon) Surgeon, Director, Moores Cancer Center, UC San Diego Health Visit 🔗 pcan.at/RightTrackLive to save your virtual seat today!

Dr. @ABerkenblit, PanCAN's Chief Scientific and Medical Officer, shares: "A new location. Record numbers of attendees, poster presentations and talks. A buzz of energy — of hope and optimism — that I’ve never seen before at a pancreatic cancer conference. This year’s PanCAN Scientific Summit was an event to remember. Hosted in sunny San Diego, the Summit brought together PanCAN’s Community for Progress, including research grant recipients, Scientific and Medical Advisory Board members, Industry Champions, patient research advocates, members of our Board of Directors and other special guests. Everyone in the room was there with a shared purpose — to turn science into survival. The opening reception showcased 27 posters, representing clinical progress from Industry Champions and scientific updates from grantees and users of our SPARK health data platform. We were also delighted to invite nine travel scholars to attend the conference — graduate students and postdoctoral fellows who displayed posters of their research projects and received feedback from experts in the field. One of the happiest outcomes was the strong comradery amongst the travel scholars — trainees who are working hard to establish their own careers as pancreatic cancer researchers and now have a network of new mentors and peers to lean on for support. As we were preparing the agenda for this year’s Scientific Summit, we knew we had to spotlight RAS — a protein mutated in more than 90% of pancreatic tumors that was considered undruggable for decades — until now. In August of this year, the first RAS-targeting drug for patients with pancreatic cancer was approved after showing a doubling of overall survival compared to chemotherapy in a recent clinical trial. Today, there are more than 80 different RAS-targeting drugs in clinical development for treating cancer. As we look forward to navigating this new era of treatment options for pancreatic cancer, we also took the opportunity to look back on what it took to get here. Three of the world’s leading experts on RAS biology — Drs. Dafna Bar-Sagi, Channing Der and Frank McCormick — sat down to discuss whether RAS would ever be a druggable target at a PanCAN Scientific Meeting back in 2016. Ten years later, we were able to reassemble the three of them alongside Dr. Brian Wolpin, the principal investigator for the RASolute-302 clinical trial that led to the approval of RASONQUE™ (daraxonrasib), for a robust discussion about the past, present and future of studying and targeting RAS. The excitement was palpable as the discussion turned to how various stakeholders — scientists, clinicians, industry, patient advocates, regulatory agencies and more — are working together to incorporate RAS inhibition into the treatment of pancreatic cancer and aiming to make it even more effective." Read more in a special edition of Dr. Berkenblit's Research Spotlight at 🔗 pcan.at/2a6a08mz.

We are saddened to acknowledge the passing of actress Susan Saint James, who died of pancreatic cancer at age 80. She was best known for her roles in the television series "McMillan & Wife" and "Kate & Allie." In 2026, an estimated 67,530 people in the U.S. will be diagnosed with pancreatic cancer and approximately 52,740 will die from the disease. Learn more about pancreatic cancer and how PanCAN is working to accelerate progress toward better outcomes for patients at 🔗 pancan.org. 📷: AP News

Pancreatic cancer is often called a “silent” disease because symptoms are rarely noticeable in its early stages. When symptoms do appear, they can be subtle or easily mistaken for other health issues. Awareness of the signs and understanding your personal risk factors are critical, and early detection dramatically improves treatment options and outcomes. 💜 Anna Berkenblit, MD, MMSc, PanCAN's Chief Scientific and Medical Officer, shares: “No one knows your body better than you. If something doesn’t feel right, don’t ignore it. Talk to your doctor and keep pushing for answers. At PanCAN, we’re working every day to make sure earlier detection and better treatments become the expectation, not the exception.” Visit 🔗 pcan.at/yh5qoo for seven common symptoms and signs of pancreatic cancer you should know.

On the latest episode of PancChat, host @AlisynCamerota is joined by Dr. Diane Reidy-Lagunes of @DukeHealth to discuss managing pancreatic neuroendocrine tumors, also known as PNETs. Visit 🔗 pcan.at/PancChat to listen. The PancChat podcast is a collaboration between @LetsWinPC and PanCAN, and this episode is sponsored by @RevMedicines. 💜

Just in time for National Pumpkin Day, these Pumpkin Oatmeal Bars are a wholesome alternative to many common cookie recipes. Made with whole-wheat flour, oats, pumpkin and ground flaxseed, they offer soluble and insoluble fiber, along with the antioxidant and phytochemical benefits of warming spices. 🎃 For people with #pancreaticcancer, flaxseed can be omitted if it causes discomfort. This recipe was developed by registered dietitians who are board-certified specialists in oncology nutrition and Meals to Heal, in collaboration with Chef Michael Ferraro. Find the full recipe and more free diet and nutrition resources for people with pancreatic cancer at 🔗 pcan.at/3wcb61os.

When Tim’s family and friends came together to honor his memory, they created something truly special: a day filled with community. 💜 Through their PanCAN Wage Hope My Way fundraiser, Jackie, Tim’s widow, their children Evan, Olivia and Grace, and a dedicated group of friends organized Team Up for Tim: Memorial Corn Hole, bringing their hometown of Everett, Massachusetts, together to celebrate Tim’s legacy. Event organizer Caitlin shared, “Jackie and the kids realized that they wanted to celebrate Tim in a way that would bring his friends and family together just as he would have wanted it.” And their community showed up in a big way. Hundreds of people gathered to play cornhole, cheer on competitors, participate in raffles, enjoy delicious food and share memories of Tim. There were moments of laughter alongside full and heavy hearts. Among those who attended were a medical student who met Tim on her first day at the hospital, as well as one of Tim’s pulmonary specialists. Catherine, the medical student, shared a moving speech about Tim and the importance of pancreatic cancer research. Research was deeply important to Tim. Before his passing from pancreatic cancer, he generously shared his medical information with doctors in the hope of advancing research and helping them better understand the disease. Team Up for Tim carried that commitment forward by raising more than $26,000 to support PanCAN’s $250 million All Together We Can campaign to turn science into survival. For the friends who helped bring the event to life, being there for Jackie and her children was about more than organizing a fundraiser. It was about showing up for a family they love and helping create a future where survival is the expectation, not the exception. Want to turn something meaningful to you into an opportunity to make a difference, just as Tim’s family and friends did? Learn more about Wage Hope My Way, PanCAN’s Innovative Fundraising Program, and create a fundraiser of your own at 🔗 pancan.org/diy.

On World Pancreatic Cancer Day, join PanCAN for a Right Track Live virtual event focused on helping patients, caregivers and loved ones better understand early detection for pancreatic cancer. 💜🔎 Leading experts in pancreatic cancer biology, imaging and surgery will share the latest in early detection research, answer common questions and provide valuable insights for anyone interested in early detection — when pancreatic cancer is most treatable. RSVP now at 🔗 pcan.at/RightTrackLive.

“I've set an aggressive goal, because it's an aggressive cancer.” For Mike G., those words became a mission: taking on the Zuma Beach Triathlon in Malibu, California, to raise funds for PanCAN. 🏊‍♂️🚴‍♂️🏃‍♂️ Mike’s motivation is deeply personal. After undergoing a distal pancreatectomy and chemotherapy, he was introduced to clinical trial opportunities involving daraxonrasib (RASONQUE) and zoldonrasib in early 2025. Having benefited from treatment advances himself, Mike says he’s feeling well and hopes his efforts will help drive progress for others facing pancreatic cancer. Through his Team PanCAN Your Way fundraiser, part of PanCAN’s Wage Hope My Way program, Mike set a goal of raising $5,000 to support PanCAN’s $250 million All Together, We Can campaign to turn science into survival. With support from his community and his pledge to match donations, Mike raised more than $15,000! After the triathlon, Mike shared this message with his supporters: “It was an experience I won't forget. Nor will I forget the way each of you rallied around this cause, all in less than a month. Thank you for championing my efforts.” Join us in congratulating Mike on this incredible accomplishment and thanking him for raising mission-critical funds to help make survival the expectation, not the exception, for people facing this disease. 💜 Are you training for a half or full marathon, taking on a triathlon or planning a cycling challenge? Turn your miles into a mission with Team PanCAN Your Way, part of PanCAN’s Wage Hope My Way program. Visit 🔗 pancan.org/diy to learn more about creating an endurance fundraiser of your own.

As a founding member of the World Pancreatic Cancer Coalition (WPCC), PanCAN is joining the global coalition once again to raise awareness this #WPCD, November 19. 🌎💜 @WorldPCC

We’re throwing it back this #FlashbackFriday to all of the remarkable ways the PanCAN community raised awareness during Pancreatic Cancer Awareness Month in 2025! 💜 As we look ahead to November, we want to hear from you: Why are you raising awareness this year? Share your why in the comments.

Join PanCAN’s live virtual events for expert-led discussions designed to help people with pancreatic cancer and their caregivers navigate their diagnosis and treatment journey. Hear practical guidance and the latest information from leading pancreatic cancer experts. Each event offers an opportunity to learn, ask questions and gain insights to make informed decisions about care. 💜 Register for upcoming events now at 🔗 pcan.at/RightTrackLive.

For Alyssa L., PanCAN's Associate Director of Philanthropic Engagement and Mid-level Giving, the mission to advance pancreatic cancer research and support patients and families hits close to home. 💜 She shares, "In January 2025, my dad was diagnosed with pancreatic cancer. I knew what people said about this disease. I had watched his mom, my grandmother, die just four months after her diagnosis in 2011. So, devastated, my dog and I moved home to make the most of the time we had left together. His initial diagnosis was stage IB. But when a Whipple procedure attempt in June 2025 revealed two small lesions in his liver, he was immediately elevated to stage IV, and the doctor estimated that he likely had only eight months to a year left. Since then, our family has been through more rounds of chemotherapy than I can count, CT scans, infections, a second failed Whipple surgery, setbacks and the agonizing uncertainty of waiting for results, return phone calls and the next appointment. If you’ve been touched by pancreatic cancer, you likely recognize this cycle of hope and grief. I knew I needed something that would get me out of bed in the morning. I felt desperate to contribute something positive and make meaningful progress for others facing this disease. That determination led me to PanCAN. Since joining the team here, I haven’t just learned about PanCAN’s mission and programs. I’ve experienced their impact firsthand. I’ve used PanCAN’s website and resources to become better informed. I’ve attended every webinar and listened to PancChat podcasts to deepen my understanding of the disease, the science and the treatment landscape. I attended my first PanCAN PurpleStride with my family and connected with other patients and caregivers, heard inspiring stories from survivors and experienced the power of a community united by hope. In conversations with our fundraising team, I’ve felt the authenticity, kindness and compassion that compels our supporters to give. My colleagues in PanCAN Patient Services answered my many questions, which strengthened both my work and helped me navigate conversations with my dad’s care team with far more clarity and confidence. When I prepared narratives about daraxonrasib and PanCAN’s decades-long role in propelling RAS research forward, I leaned heavily on my colleagues’ expertise to grasp the significance of this breakthrough. They also helped me understand the trial results and what they could mean for patients like my dad. So, when another liver lesion finally showed up on his imaging this July, I already knew our next step: trying to get him into the expanded access program (EAP) for daraxonrasib. On August 25th, when his paperwork was finally submitted, I felt hopeful knowing we were on the path to keep just barely outrunning this cancer for a little while longer. The next day, RASONQUE™ (daraxonrasib) was approved by the FDA. As PanCAN shared the exciting news, I was simultaneously panicking about what it might mean for my dad’s access, particularly after a month off treatment. Luckily, PanCAN’s Patient Services team provides personalized guidance for people exactly like me. I called, and they knew what my next steps should be. On their guidance, we got back on track to access the treatment through insurance. Colleagues had already been checking in because they knew others were running into access issues, and they were hard at work telling the story of how to better advocate for patients and their loved ones. So I wasn’t all that surprised when my dad was denied coverage. After a firm discussion with the insurance company, and armed with the knowledge I’d gained from Patient Services, we received a reversal — and RASONQUE arrived at our door the next day. My dad’s been on RASONQUE for a month, and his numbers are looking good. I know RASONQUE isn’t a cure. But right now, this treatment is giving my family renewed hope for more time. For more than 27 years, PanCAN President and CEO Julie Fleshman and Founder Pamela Acosta Marquardt have brought passion, unwavering dedication and ingenuity to PanCAN’s mission. Their commitment has been relentless, shaping and strengthening the field in countless ways. PanCAN’s willingness to be bold and innovative, to invest in RAS research 20 years ago when those mutations were considered undruggable, played a role in getting us to this moment. And the work we’re advancing today will continue to drive future breakthroughs for patients. I’m so honored to be a part of it. To my colleagues at PanCAN — and to everyone who donates, volunteers, walks, and advocates — you are changing people’s lives. I know, because I’m one of them." Join us in sharing some love and support for Alyssa and her family in the comments. 💜

Register for #PanCANPurpleStride 2027 and start reconnecting with your community, fundraising and making an impact toward a future where survival is the expectation, not the exception. 💜 Registering will give you access to your personal PurpleStride Dashboard. And this year, we’ve made fundraising easier than ever with the PanCAN Fundraising mobile app! The Dashboard and the app are your one-stop shop for your fundraising needs, but the app has bonus features you should take advantage of, like: 🔎 A personal QR code Your app gives you a unique QR code that links directly to your Personal Fundraising Page. Display it, download it or share it — supporters can simply scan and donate. 💬 Reaching supporters by text or WhatsApp Send pre-written fundraising messages to your network by text or WhatsApp, in addition to email. 📲 Sharing wherever you’re social Copy your Personal Fundraising Page link and share it on Instagram, Facebook, LinkedIn or TikTok. And it’s not just convenient — Striders who use an app to fundraise raise 2.4 times more than those who don’t! Register at 🔗 purplestride.org, then download the PanCAN Fundraising app today!

Take the trip of a lifetime climbing to the roof of Africa while creating a world where every patient with pancreatic cancer survives. Join an exclusive, first-class charity trek, fully guided by our excursion partner Embark Exploration Co., and discover what’s possible when purpose meets adventure. 💜 Ready to learn more? Register for our PanCAN Summit for Survival: Kilimanjaro 2027 Information Session at 🔗 pcan.at/adventure.

Today, we remember @NBA referee Tony Brown on the anniversary of his passing from pancreatic cancer. He was 55. Tony’s daughter, PanCAN Ambassador Bailey Taylor Brown, honors her dad’s legacy by raising awareness, fundraising in his memory and leading Team Tony Brown #6Strong at #PanCANPurpleStride. Thank you, Bailey, for allowing us to honor and remember your dad alongside you. 💜 Join us in sending love to the Brown family, the @OfficialNBARefs and everyone who knew and loved Tony in the comments. Learn more about pancreatic cancer and how, together, we can turn survival into the expectation, not the exception, for everyone facing this disease at 🔗 pancan.org.

PanCAN volunteers are hope in action. 💜 PurpleStriders leaders, Volunteer Advisory Council (VAC) members and National Volunteer Awards recipients from across the country recently came together in Dallas for our National Affiliate Forum. Together, they built connections, learned from one another, honored their whys and explored ways to lead with impact, raise mission-critical funds in their communities and advance PanCAN’s mission to turn science into survival. Each #PanCANvolunteer also received a heartfelt, handwritten note from a pancreatic cancer researcher or clinician, written weeks earlier at our Scientific Summit — a meaningful reminder that we’re all part of something bigger and that, all together, we can change the story of this disease. Want to make a difference in your community? Visit 🔗 pancan.org/getinvolved to learn more about becoming a PanCAN volunteer!