Researchers have developed an AI-based approach to help physicians with real-life clinical workups, starting with the patient’s chief complaint, systematically asking questions and deciding what laboratory and imaging tests to order, and then continuing the evaluation on the basis of the answers received. Learn more this week in Science: scim.ag/3U8xn94

In the 1950s, scientists tried to define "normal" humans. The problem? They couldn't find any. The Normals, a #SciencePodcast🎙️ series that explores this story, has won Silver in the Science & Education: Limited Series and Specials category at the @signalawards! Check out the award-winning series: scim.ag/4bWMKr9

Researchers in Science report that many birds use vertical winds or gradual changes in wind speed or direction (wind shear) to soar, thereby reducing their cost of transport by switching from costly flapping flight to gliding flight. 📄: scim.ag/4dJr0Qc #SciencePerspective: scim.ag/4yVNzth

🐟 How many times have fish evolved suction cups? Research led by Scripps PhD student Emily McFarland found that suction cups evolved at least 3 times independently in nearly 1,000 fish species! Dive into the study featured in @ScienceMagazine. ⤵️ science.org/content/article/…

We didn't know about the role of alternative RNA splicing for response to cancer immunotherapy. Discovery of STAT2 introns that influence non-small cell lung cancer response and survival (PSI=percent spliced in) @ScienceMagazine science.org/doi/10.1126/scie…

Using genome editing to trace cell lineages, researchers have captured the early history of the mouse embryo in unprecedented detail. Learn more: scim.ag/4z5PhIP @NewsfromScience

A new device can detect scents and transmit them between people across distances, with the potential for long-range transmission. It marks another stage in the development of human-machine interfaces: enabling the sharing of smell. Learn more in @ScienceAdvances: scim.ag/47z6fTL

Researchers in Science have developed an AI-based approach to help physicians with real-life clinical workups. The system shows promise in supplementing a physician’s workflow. Learn more: scim.ag/4sfzsfP

Imagine a system for people with diabetes that could continuously monitor glucose and keep its level steady and under control without drugs. Oh, here it is, at least one that works well in mice @ScienceMagazine science.org/doi/10.1126/scie…

A new slate of #optogenetic tools enables scientists to finely control G protein signaling in excitable cells—providing a flexible method that might also be used therapeutically for disorders that disrupt the excitability of cells. @SciSignal scim.ag/4eImxxk

Just in time for the World Series, the "robot-ump" science.org/content/article/… by @sciencecohen @ScienceMagazine

Just published @ScienceMagazine Higher medical accuracy at lower cost A 3-agent AI for sequential diagnosis nearly doubled accuracy compared with physicians for >300 @NEJM CPC cases and >300 ER cases AND substantially lowered cost, also exceeded performance of many AI models, physicians plus AI @HarshaNori @erichorvitz @Dominic1King @mustafasuleyman

Science is publishing an Erratum to replace the June 2026 Editorial Expression of Concern for the September 2024 Research Article “Durably reducing conspiracy beliefs through dialogues with AI.” scim.ag/4dPOWRT

Last chance: Apply for the BioInnovation Institute & #ScienceTranslationalMedicine Prize for Innovations in Women’s Health This prize recognizes researchers who have developed innovative advances with translational potential to impact women’s health globally. The Grand Prize winner will be awarded a cash prize of USD 25,000 and have their winning essay published online in Science Translational Medicine. Apply by 1 November 2026: bit.ly/4APCJGP

STAT3 is a cytokine-sensitive switch regulating NK cell differentiation in a mouse model of antiviral response. Learn more in @SciImmunology about the study’s possible implications for STAT3 immunotherapy and cancer progression: scim.ag/3WsoUhy

2026's @ScienceMagazine Top Employers: From AI to I do AI is a bigger consideration for job seekers this year, but some things don't change: scientists want to work where science and people are prized. Discover this year’s rankings: bit.ly/3WHm5t5 #SCTopEmployers

An implantable, wirelessly powered electronic device could offer a drug-free approach to managing the intertwined metabolic disorders of obesity and type 2 diabetes. The device uses electrocatalysis to remove excess glucose from the bloodstream on demand. Learn more in Science: scim.ag/47twScK

Home decorating isn’t unique to Homo sapiens. More than 40,000 years ago, bands of Neanderthals turned a spacious rock shelter in the mountains of Spain into a cozy home, fashioning wood into tools and windbreaks and burning it for heat and light. That picture comes from a first-of-its-kind trove of Neanderthal wooden artifacts from a domestic space, found at a cliffside site called Abric Romaní, 50 kilometers west of Barcelona. Learn more: scim.ag/3VK5zZb @NewsfromScience

By applying a unique polyene scaffold, researchers engineer a next-generation, broad-spectrum antifungal that selectively targets ergosterol without binding to cholesterol, avoiding severe toxicity linked to drugs like amphotericin B. Find out more in @ScienceTM: scim.ag/3UycT9T

Animals and plants use conceptually similar immune systems to detect microbes and activate defenses. In both lineages, pattern recognition receptors (PRRs) perceive pathogen- or microbe-associated molecular patterns (PAMPs or MAMPs) and host-derived damage-associated molecular patterns (DAMPs). Whereas animals rely on specialized immune cells, plants harness individual cells expressing diverse PRRs. In the apoplast, which lies outside the plasma membrane and includes the cell wall, PRRs detect immunogenic fragments released from microbial proteins by plant hydrolytic enzymes. Conversely, pathogen-secreted enzymes can degrade constituents of the apoplast, generating DAMPs that activate immunity. In three new Science papers, researchers report expansions of this surveillance, revealing receptor architectures and mechanisms that enable plants to discriminate immunogenic carbohydrates. The findings illustrate how ligand specificity and receptor assembly confine immune activation to the context of microbial challenge. Learn more in a new #SciencePerspective: scim.ag/4ib9BRC