Biostatistician at Memorial Sloan Kettering Cancer Center. Special interest in prostate cancer, risk prediction, patient-reported outcomes, decision-making.
New York
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Lymphocele cited as major reason in guidelines to avoid LND in prostate cancer. Here we show most almost all lymphoceles (42/43) come from Cloquet's node, which should not be removed during LND. auajournals.org/doi/10.1097/…
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mm pattern 4 on biopsy far superior predictor of prostate cancer outcome than stage, grade, PSA, cores. We show using mm criteria rather than "favorable intermediate risk" would increase the number of US men eligible for active surveillance by >50,000. bjui-journals.onlinelibrary.…
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"When we tell a patient they have prostate cancer, we mean the pathologist has looked at prostate biopsy cores under a microscope and saw areas without a basal cell layer; what the patient hears, however, is something entirely different" academic.oup.com/jnci/advanc…
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Andrew Vickers retweeted
🎯 There is no Goldilocks word right for every patient. But we can choose our words, and those choices influence.
🙋♂️ We used prostate cancer as the case study, but the strategies apply today, and to new terms as they emerge across medicine.
🎙️Let's start this dialogue today
🔗 doi.org/10.1097/JU.000000000…
@AmerUrological @PCFnews @UroOnc @SUO_YUO @UclaUrology @CedarsSinai @UrologyTimes @Uro_Res @dr_coops @TylerSbrt @AmarUKishan @KamravaMD @AnthonyNguyenMD @daviesbj @theusinghal @JackAndrewsMD @VickersBiostats @MichaelAhdootMD
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Join us next week for two days focused on the latest advances, evolving treatment strategies, and key clinical questions in #ProstateCancer care.
Through tumor boards, panel discussions, and head-to-head debates, multidisciplinary experts from @MSKCancerCenter and guest speakers, @Chris_Barbieri1 and @mishabeltran, will explore the full continuum of care — from screening, biomarkers, and advanced imaging to active surveillance, focal therapy, high-risk and metastatic disease, PSMA PET, radioligand therapy, PARP inhibition, and precision treatment strategies.
We hope to see you in New York or virtually, October 8–9. Learn more and register: bit.ly/Prostate2026CME
#MSKprostateCME
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Andrew Vickers retweeted
This is CRAZY. The test didn’t meet its endpoint and the study was not designed to assess harm and showed no benefit.
reuters.com/business/healthc…
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Empirical evidence pattern 3 prostate disease does not meet the ordinary language definition of "cancer". It cannot “invade and destroy” local structures; recurrence is due to residual tissue.
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WSJ: MCED "Proven to save lives". Any statisticians / early cancer detection experts want to join me in an editorial in say, Statistics in Medicine, about what the data prove about the economy? wsj.com/opinion/a-grail-canc…
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Netto et al published an argument against relabeling pattern 3 prostate disease as pre-cancerous: pattern 3 but not benign shares “canonical molecular alterations” with pattern 4. A literature review shows this to be false @uroegg @dr_coops bjui-journals.onlinelibrary.…
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I have been asked by reviewers to "soften" the conclusions. Can anyone explain what this means?
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I've been doing prostate cancer epidemiology for more than 20 years and never realized these two were related.
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Testosterone therapy in men on active surveillance for prostate cancer is not associated with increased risk of disease progression auajournals.org/doi/10.1097/…
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Can anyone at AMA please explain to be the rationale of insisting on two significant figures for high p values but one significant figure for lower p values? The 4 in p=0.34 tells us nothing; truncating the 4 so p=0.034 is changed to 0.03 is losing information.
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On the left, Robin meets his hero, Jimmy Mickle, at frisbee summer camp, 2018. On the right, Robin and Jimmy after Robin's team, San Francisco Revolver, defeats Jimmy's (New York Pony) in the World Ultimate Club Championship final.
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Almost all high-income countries have a national policy recommending shared decision-making before PSA screening. We show: a) this recommendation never justified by evidence; b) best evidence is PSA screening not a preference-sensitive decision. journals.sagepub.com/eprint/…
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Generally assumed population-based PSA screening = increased overdiagnosis. But already lots of PSA testing going on. In a modeling study, we show organized screening would reduce PSA tests, overdiagnosis compared to current disorganized approach
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Can everyone stop using the term "real world data" and just be precise about setting, participants and interventions? grandroundsinurology.com/the…
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I've long been suspicious of "regret" as an endpoint. This is principally because decisional regret is predicated on the (improbable) understanding of outcome under the counterfactual. New paper shows regret is basically explained by "I had a bad outcome". pubmed.ncbi.nlm.nih.gov/4242…
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